IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2008 180: 4349-4350. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

More Than Just Vanilla

Pamela J. Fink
J Immunol 2008 180: 4351-4352. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Theta Isoantigen as a Marker of Thymus-Derived Lymphocytes in Mice. Nature 1969. 224: 378–379.

Martin C. Raff
J Immunol 2008 180: 4353-4354. [PDF]  

BRIEF REVIEWS:

Modulation of Dendritic Cell Function by Leishmania Parasites

Lynn Soong
J Immunol 2008 180: 4355-4360. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Langerin⁺ Dendritic Cells in the Mesenteric Lymph Node Set the Stage for Skin and Gut Immune System Cross-Talk

Sun-Young Chang, Hye-Ran Cha, Osamu Igarashi, Paul D. Rennert, Adrien Kissenpfennig, Bernard Malissen, Masanobu Nanno, Hiroshi Kiyono, and Mi-Na Kweon
J Immunol 2008 180: 4361-4365. [Abstract] [Full Text] [PDF]  

Cutting Edge: Autoimmune Disease in Day 3 Thymectomized Mice Is Actively Controlled by Endogenous Disease-Specific Regulatory T Cells

Eileen T. Samy, Karen M. Wheeler, Randall J. Roper, Cory Teuscher, and Kenneth S. K. Tung
J Immunol 2008 180: 4366-4370. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Dendritic Cell Differentiation State and Their Interaction with NKT Cells Determine Th1/Th2 Differentiation in the Murine Model of Leishmania major Infection

Carsten Wiethe, Andrea Debus, Markus Mohrs, Alexander Steinkasserer, Manfred Lutz, and André Gessner
J Immunol 2008 180: 4371-4381. [Abstract] [Full Text] [PDF]  

CD40 on APCs Is Needed for Optimal Programming, Maintenance, and Recall of CD8⁺ T Cell Memory Even in the Absence of CD4⁺ T Cell Help

Maria Genevive H. Hernandez, Lianjun Shen, and Kenneth L. Rock
J Immunol 2008 180: 4382-4390. [Abstract] [Full Text] [PDF]  

IL-15 Transpresentation Augments CD8⁺ T Cell Activation and Is Required for Optimal Recall Responses by Central Memory CD8⁺ T Cells

Andy I. Kokaji, Deanna L. Hockley, and Kevin P. Kane
J Immunol 2008 180: 4391-4401. [Abstract] [Full Text] [PDF]  

AML1/Runx1 Negatively Regulates Quiescent Hematopoietic Stem Cells in Adult Hematopoiesis

Motoshi Ichikawa, Susumu Goyama, Takashi Asai, Masahito Kawazu, Masahiro Nakagawa, Masataka Takeshita, Shigeru Chiba, Seishi Ogawa, and Mineo Kurokawa
J Immunol 2008 180: 4402-4408. [Abstract] [Full Text] [PDF]  

Lack of TIM-3 Immunoregulation in Multiple Sclerosis

Li Yang, David E. Anderson, Juhi Kuchroo, and David A. Hafler
J Immunol 2008 180: 4409-4414. [Abstract] [Full Text] [PDF]  

Innate-Like Effector Differentiation of Human Invariant NKT Cells Driven by IL-7

Claudia de Lalla, Nicola Festuccia, Inka Albrecht, Hyun-Dong Chang, Grazia Andolfi, Ulrike Benninghoff, Ferdinando Bombelli, Giovanna Borsellino, Alessandro Aiuti, Andreas Radbruch, Paolo Dellabona, and Giulia Casorati
J Immunol 2008 180: 4415-4424. [Abstract] [Full Text] [PDF]  

Inhibition of TLR Activation and Up-Regulation of IL-1R-Associated Kinase-M Expression by Exogenous Gangliosides

Weiping Shen, Kelly Stone, Alessandra Jales, David Leitenberg, and Stephan Ladisch
J Immunol 2008 180: 4425-4432. [Abstract] [Full Text] [PDF]  

CD4⁺CD25⁺ Regulatory T Cells Specific for a Thymus-Expressed Antigen Prevent the Development of Anaphylaxis to Self

Stefano Scabeni, Marilena Lapilla, Silvia Musio, Barbara Gallo, Emilio Ciusani, Lawrence Steinman, Renato Mantegazza, and Rosetta Pedotti
J Immunol 2008 180: 4433-4440. [Abstract] [Full Text] [PDF]  

Gastrointestinal Dendritic Cells Promote Th2 Skewing via OX40L

Ana Belén Blázquez and M. Cecilia Berin
J Immunol 2008 180: 4441-4450. [Abstract] [Full Text] [PDF]  

Loss of IFN- Enables the Expansion of Autoreactive CD4⁺ T Cells to Induce Experimental Autoimmune Encephalomyelitis by a Nonencephalitogenic Myelin Variant Antigen

Joseph J. Sabatino, Jr., John Shires, John D. Altman, Mandy L. Ford, and Brian D. Evavold
J Immunol 2008 180: 4451-4457. [Abstract] [Full Text] [PDF]  

Autoimmunity to Both Proinsulin and IGRP Is Required for Diabetes in Nonobese Diabetic 8.3 TCR Transgenic Mice

Balasubramanian Krishnamurthy, Lina Mariana, Shane A. Gellert, Peter G. Colman, Leonard C. Harrison, Andrew M. Lew, Pere Santamaria, Helen E. Thomas, and Thomas W. H. Kay
J Immunol 2008 180: 4458-4464. [Abstract] [Full Text] [PDF]  

Impact of Post-Thymic Cellular Longevity on the Development of Age-Associated CD4⁺ T Cell Defects

Stephen C. Jones, Karen Clise-Dwyer, Gail Huston, John Dibble, Sheri Eaton, Laura Haynes, and Susan L. Swain
J Immunol 2008 180: 4465-4475. [Abstract] [Full Text] [PDF]  

Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways

Sarah R. Jacobs, Catherine E. Herman, Nancie J. MacIver, Jessica A. Wofford, Heather L. Wieman, Jeremy J. Hammen, and Jeffrey C. Rathmell
J Immunol 2008 180: 4476-4486. [Abstract] [Full Text] [PDF]  

De Novo Production of K-1 Tubulin-Specific Antibodies: Role in Chronic Lung Allograft Rejection

Trudie A. Goers, Sabarinathan Ramachandran, Aviva Aloush, Elbert Trulock, G. Alexander Patterson, and Thalachallour Mohanakumar
J Immunol 2008 180: 4487-4494. [Abstract] [Full Text] [PDF]  

In Vivo Regulation of Experimental Autoimmune Encephalomyelitis by NK Cells: Alteration of Primary Adaptive Responses

Robin Winkler-Pickett, Howard A. Young, James M. Cherry, John Diehl, John Wine, Timothy Back, William E. Bere, Anna T. Mason, and John R. Ortaldo
J Immunol 2008 180: 4495-4506. [Abstract] [Full Text] [PDF]  

Brief Antigenic Stimulation Generates Effector CD8 T Cells with Low Cytotoxic Activity and High IL-2 Production

David Usharauli and Tirumalai Kamala
J Immunol 2008 180: 4507-4513. [Abstract] [Full Text] [PDF]  

Assessment of Bet v 1-Specific CD4⁺ T Cell Responses in Allergic and Nonallergic Individuals Using MHC Class II Peptide Tetramers

Laurence Van Overtvelt, Erik Wambre, Bernard Maillère, Eric von Hofe, Anne Louise, Anne Marie Balazuc, Barbara Bohle, Didier Ebo, Christophe Leboulaire, Gilles Garcia, and Philippe Moingeon
J Immunol 2008 180: 4514-4522. [Abstract] [Full Text] [PDF]  

Selective Roles of MAPKs during the Macrophage Response to IFN-

Annabel F. Valledor, Ester Sánchez-Tilló, Luis Arpa, Jin Mo Park, Carme Caelles, Jorge Lloberas, and Antonio Celada
J Immunol 2008 180: 4523-4529. [Abstract] [Full Text] [PDF]  

Aberrant Genetic Control of Invariant TCR-Bearing NKT Cell Function in New Zealand Mouse Strains: Possible Involvement in Systemic Lupus Erythematosus Pathogenesis

Kazuyuki Tsukamoto, Mareki Ohtsuji, Wakana Shiroiwa, Qingshun Lin, Kazuhiro Nakamura, Hiromichi Tsurui, Yi Jiang, Katsuko Sudo, Hiroyuki Nishimura, Toshikazu Shirai, and Sachiko Hirose
J Immunol 2008 180: 4530-4539. [Abstract] [Full Text] [PDF]  

Inducing Antitumor T Cell Immunity: Comparative Functional Analysis of Interstitial Versus Langerhans Dendritic Cells in a Human Cell Line Model

Saskia J. A. M. Santegoets, Hetty J. Bontkes, Anita G. M. Stam, Farien Bhoelan, Janneke J. Ruizendaal, Alfons J. M. van den Eertwegh, Erik Hooijberg, Rik J. Scheper, and Tanja D. de Gruijl
J Immunol 2008 180: 4540-4549. [Abstract] [Full Text] [PDF]  

Human Cytomegalovirus Infection Induces a Rapid and Sustained Change in the Expression of NK Cell Receptors on CD8⁺ T Cells

Amber van Stijn, Ajda T. Rowshani, Sila L. Yong, Frank Baas, Eddy Roosnek, Ineke J. M. ten Berge, and René A. W. van Lier
J Immunol 2008 180: 4550-4560. [Abstract] [Full Text] [PDF]  

Dendritic Cell-Dependent Inhibition of B Cell Proliferation Requires CD22

Lorna Santos, Kevin E. Draves, Mark Boton, Prabhjit K. Grewal, Jamey D. Marth, and Edward A. Clark
J Immunol 2008 180: 4561-4569. [Abstract] [Full Text] [PDF]  

TRAIL Deficiency Does Not Rescue Impaired CD8⁺ T Cell Memory Generated in the Absence of CD4⁺ T Cell Help

Jilian A. Sacks and Michael J. Bevan
J Immunol 2008 180: 4570-4576. [Abstract] [Full Text] [PDF]  

Immunodominance in the TCR Repertoire of TCR Peptide-Specific CD4⁺ Treg Population That Controls Experimental Autoimmune Encephalomyelitis

Loui Thomas Madakamutil, Igor Maricic, Eli E. Sercarz, and Vipin Kumar
J Immunol 2008 180: 4577-4585. [Abstract] [Full Text] [PDF]  

Activation and Function of the mTORC1 Pathway in Mast Cells

Mi-Sun Kim, Hye Sun Kuehn, Dean D. Metcalfe, and Alasdair M. Gilfillan
J Immunol 2008 180: 4586-4595. [Abstract] [Full Text] [PDF]  

Induction of Antitumor Immune Response by Homeostatic Proliferation and CD28 Signaling

Toshihiro Suzuki, Shuhei Ogawa, Kazunari Tanabe, Hideaki Tahara, Ryo Abe, and Hidehiro Kishimoto
J Immunol 2008 180: 4596-4605. [Abstract] [Full Text] [PDF]  

Intracellular Retention of the NKG2D Ligand MHC Class I Chain-Related Gene A in Human Melanomas Confers Immune Privilege and Prevents NK Cell-Mediated Cytotoxicity

Mercedes B. Fuertes, María V. Girart, Luciana L. Molinero, Carolina I. Domaica, Lucas E. Rossi, María M. Barrio, José Mordoh, Gabriel A. Rabinovich, and Norberto W. Zwirner
J Immunol 2008 180: 4606-4614. [Abstract] [Full Text] [PDF]  

Invariant NKT Cells Promote CD8⁺ Cytotoxic T Cell Responses by Inducing CD70 Expression on Dendritic Cells

Vadim Y. Taraban, Sonya Martin, Kathrine E. Attfield, Martin J. Glennie, Tim Elliott, Dirk Elewaut, Serge Van Calenbergh, Bruno Linclau, and Aymen Al-Shamkhani
J Immunol 2008 180: 4615-4620. [Abstract] [Full Text] [PDF]  

NK Cells Contribute to Intracellular Bacterial Infection-Mediated Inhibition of Allergic Responses

Xiaobing Han, Yijun Fan, Shuhe Wang, Lei Jiao, Hongyu Qiu, and Xi Yang
J Immunol 2008 180: 4621-4628. [Abstract] [Full Text] [PDF]  

Villous B Cells of the Small Intestine Are Specialized for Invariant NK T Cell Dependence

Peter Velázquez, Bo Wei, Michael McPherson, Lesley Marie A. Mendoza, Sandra L. Nguyen, Olga Turovskaya, Mitchell Kronenberg, Tiffany T. Huang, Matthew Schrage, Lynn N. Lobato, Daisuke Fujiwara, Sarah Brewer, Moshe Arditi, Genhong Cheng, R. Balfour Sartor, Rodney D. Newberry, and Jonathan Braun
J Immunol 2008 180: 4629-4638. [Abstract] [Full Text] [PDF] Data Supplement  

Multivectorial Abnormal Cell Migration in the NOD Mouse Thymus

Daniella A. Mendes-da-Cruz, Salete Smaniotto, Alexandre C. Keller, Mireille Dardenne, and Wilson Savino
J Immunol 2008 180: 4639-4647. [Abstract] [Full Text] [PDF]  

Mast Cell Migration from the Skin to the Draining Lymph Nodes upon Ultraviolet Irradiation Represents a Key Step in the Induction of Immune Suppression

Scott N. Byrne, Alberto Y. Limón-Flores, and Stephen E. Ullrich
J Immunol 2008 180: 4648-4655. [Abstract] [Full Text] [PDF]  

Developmental Control of Integrin Expression Regulates Th2 Effector Homing

Seung-Hyo Lee, Joseph E. Prince, Muhammad Rais, Farrah Kheradmand, Christie M. Ballantyne, Gabriele Weitz-Schmidt, C. Wayne Smith, and David B. Corry
J Immunol 2008 180: 4656-4667. [Abstract] [Full Text] [PDF]  

Protein Kinase C and Differentially Regulate Death-Inducing Signaling Complex Formation in Cigarette Smoke Extract-Induced Apoptosis

Jeong-Woong Park, Hong Pyo Kim, Seon-Jin Lee, Xue Wang, Yong Wang, Emeka Ifedigbo, Simon C. Watkins, Motoi Ohba, Stefan W. Ryter, Yatin M. Vyas, and Augustine M. K. Choi
J Immunol 2008 180: 4668-4678. [Abstract] [Full Text] [PDF]  

Regulatory T Cells Control Dendritic Cell/NK Cell Cross-Talk in Lymph Nodes at the Steady State by Inhibiting CD4⁺ Self-Reactive T Cells

Magali Terme, Nathalie Chaput, Behazine Combadiere, Averil Ma, Toshiaki Ohteki, and Laurence Zitvogel
J Immunol 2008 180: 4679-4686. [Abstract] [Full Text] [PDF]  

Renal Cell Carcinoma Tumors Induce T Cell Apoptosis through Receptor-Dependent and Receptor-Independent Pathways

Tanya Das, Gaurisankar Sa, Ewa Paszkiewicz-Kozik, Cynthia Hilston, Luis Molto, Patricia Rayman, Daisuke Kudo, Kaushik Biswas, Ronald M. Bukowski, James H. Finke, and Charles S. Tannenbaum
J Immunol 2008 180: 4687-4696. [Abstract] [Full Text] [PDF]  

Hypoxia and Hypoxia-Inducible Factor-1 Modulate Lipopolysaccharide-Induced Dendritic Cell Activation and Function

Jonathan Jantsch, Dipshikha Chakravortty, Nadine Turza, Alexander T. Prechtel, Björn Buchholz, Roman G. Gerlach, Melanie Volke, Joachim Gläsner, Christina Warnecke, Michael S. Wiesener, Kai-Uwe Eckardt, Alexander Steinkasserer, Michael Hensel, and Carsten Willam
J Immunol 2008 180: 4697-4705. [Abstract] [Full Text] [PDF]  

TIM-4 Expressed on APCs Induces T Cell Expansion and Survival

Roselynn Rodriguez-Manzanet, Jennifer Hartt Meyers, Savithri Balasubramanian, Jacqueline Slavik, Nasim Kassam, Valerie Dardalhon, Edward A. Greenfield, Ana C. Anderson, Raymond A. Sobel, David A. Hafler, Terry B. Strom, and Vijay K. Kuchroo
J Immunol 2008 180: 4706-4713. [Abstract] [Full Text] [PDF]  

Combined CXCR3/CCR5 Blockade Attenuates Acute and Chronic Rejection

Gabriel T. Schnickel, Sam Bastani, George R. Hsieh, Ali Shefizadeh, Rubina Bhatia, Michael C. Fishbein, John Belperio, and Abbas Ardehali
J Immunol 2008 180: 4714-4721. [Abstract] [Full Text] [PDF]  

Langerin Expressing Cells Promote Skin Immune Responses under Defined Conditions

Liangchun Wang, Laura S. Bursch, Adrien Kissenpfennig, Bernard Malissen, Stephen C. Jameson, and Kristin A. Hogquist
J Immunol 2008 180: 4722-4727. [Abstract] [Full Text] [PDF]  

B Cell Receptor Basal Signaling Regulates Antigen-Induced Ig Light Chain Rearrangements

Brian R. Schram, Lina E. Tze, Laura B. Ramsey, Jiabin Liu, Lydia Najera, Amanda L. Vegoe, Richard R. Hardy, Keli L. Hippen, Michael A. Farrar, and Timothy W. Behrens
J Immunol 2008 180: 4728-4741. [Abstract] [Full Text] [PDF]  

Homeostasis and Effector Function of Lymphopenia-Induced "Memory-Like" T Cells in Constitutively T Cell-Depleted Mice

David Voehringer, Hong-Erh Liang, and Richard M. Locksley
J Immunol 2008 180: 4742-4753. [Abstract] [Full Text] [PDF]  

CD4⁺ T Lymphocytes Are Not Necessary for the Acute Rejection of Vascularized Mouse Lung Transplants

Andrew E. Gelman, Mikio Okazaki, Jiaming Lai, Christopher G. Kornfeld, Friederike H. Kreisel, Steven B. Richardson, Seiichiro Sugimoto, Jeremy R. Tietjens, G. Alexander Patterson, Alexander S. Krupnick, and Daniel Kreisel
J Immunol 2008 180: 4754-4762. [Abstract] [Full Text] [PDF]  

TLR-Activated B Cells Suppress T Cell-Mediated Autoimmunity

Vicky Lampropoulou, Kai Hoehlig, Toralf Roch, Patricia Neves, Elisabeth Calderón Gómez, Claire H. Sweenie, Yi Hao, Antonio A. Freitas, Ulrich Steinhoff, Stephen M. Anderton, and Simon Fillatreau
J Immunol 2008 180: 4763-4773. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Doc2 and Munc13-4 Regulate Ca²⁺-Dependent Secretory Lysosome Exocytosis in Mast Cells

Hironori Higashio, Noriyuki Nishimura, Hiroyoshi Ishizaki, Jun Miyoshi, Satoshi Orita, Ayuko Sakane, and Takuya Sasaki
J Immunol 2008 180: 4774-4784. [Abstract] [Full Text] [PDF]  

Isoform-Specific Inhibition of ROR-Mediated Transcriptional Activation by Human FOXP3

Jianguang Du, Chunjian Huang, Baohua Zhou, and Steven F. Ziegler
J Immunol 2008 180: 4785-4792. [Abstract] [Full Text] [PDF]  

Intercellular Adhesion Molecule-3 Binding of Integrin _Lβ₂ Requires Both Extension and Opening of the Integrin Headpiece

Xiao-Yan Tang, Yan-Feng Li, and Suet-Mien Tan
J Immunol 2008 180: 4793-4804. [Abstract] [Full Text] [PDF]  

STAT3-Mediated Up-Regulation of BLIMP1 Is Coordinated with BCL6 Down-Regulation to Control Human Plasma Cell Differentiation

Sean A. Diehl, Heike Schmidlin, Maho Nagasawa, Simon D. van Haren, Mark J. Kwakkenbos, Etsuko Yasuda, Tim Beaumont, Ferenc A. Scheeren, and Hergen Spits
J Immunol 2008 180: 4805-4815. [Abstract] [Full Text] [PDF]  

Nonhuman Primate IgA: Genetic Heterogeneity and Interactions with CD89

Kenneth A. Rogers, Lakshmi Jayashankar, Franco Scinicariello, and Roberta Attanasio
J Immunol 2008 180: 4816-4824. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Leishmania major-Specific B Cells Are Necessary for Th2 Cell Development and Susceptibility to L. major LV39 in BALB/c Mice

Catherine Ronet, Heike Voigt, Hayo Himmelrich, Marie-Agnès Doucey, Yazmin Hauyon-La Torre, Mélanie Revaz-Breton, Fabienne Tacchini-Cottier, Claude Bron, Jacques Louis, and Pascal Launois
J Immunol 2008 180: 4825-4835. [Abstract] [Full Text] [PDF]  

Dendritic Cell Programming by Cytomegalovirus Stunts Naive T Cell Responses via the PD-L1/PD-1 Pathway

Chris A. Benedict, Andrea Loewendorf, Zacarias Garcia, Bruce R. Blazar, and Edith M. Janssen
J Immunol 2008 180: 4836-4847. [Abstract] [Full Text] [PDF]  

Age-Related Dysregulation of CD8⁺ T Cell Memory Specific for a Persistent Virus Is Independent of Viral Replication

Anna Lang, James D. Brien, Ilhem Messaoudi, and Janko Nikolich-Zugich
J Immunol 2008 180: 4848-4857. [Abstract] [Full Text] [PDF]  

Complement Factor H-Binding Protein, a Putative Virulence Determinant of Borrelia hermsii, Is an Antigenic Target for Protective B1b Lymphocytes

Matthew J. Colombo and Kishore R. Alugupalli
J Immunol 2008 180: 4858-4864. [Abstract] [Full Text] [PDF]  

TLR2-Dependent MyD88 Signaling Contributes to Early Host Defense in Murine Enterococcus faecium Peritonitis

Masja Leendertse, Rob J. L. Willems, Ida A. J. Giebelen, Petra S. van den Pangaart, W. Joost Wiersinga, Alex F. de Vos, Sandrine Florquin, Marc J. M. Bonten, and Tom van der Poll
J Immunol 2008 180: 4865-4874. [Abstract] [Full Text] [PDF]  

Blockade of PD-1/B7-H1 Interaction Restores Effector CD8⁺ T Cell Responses in a Hepatitis C Virus Core Murine Model

John R. Lukens, Michael W. Cruise, Matthew G. Lassen, and Young S. Hahn
J Immunol 2008 180: 4875-4884. [Abstract] [Full Text] [PDF]  

Mouse Mast Cell Tryptase mMCP-6 Is a Critical Link between Adaptive and Innate Immunity in the Chronic Phase of Trichinella spiralis Infection

Kichul Shin, Gerald F. M. Watts, Hans C. Oettgen, Daniel S. Friend, Alan D. Pemberton, Michael F. Gurish, and David M. Lee
J Immunol 2008 180: 4885-4891. [Abstract] [Full Text] [PDF]  

Relative Levels of M-CSF and GM-CSF Influence the Specific Generation of Macrophage Populations during Infection with Mycobacterium tuberculosis

David M. Higgins, Joaquin Sanchez-Campillo, Adrian G. Rosas-Taraco, Jonathan R. Higgins, Eric J. Lee, Ian M. Orme, and Mercedes Gonzalez-Juarrero
J Immunol 2008 180: 4892-4900. [Abstract] [Full Text] [PDF]  

Retargeting of Human T Cells to Tumor-Associated MUC1: The Evolution of a Chimeric Antigen Receptor

Scott Wilkie, Gianfranco Picco, Julie Foster, David M. Davies, Sylvain Julien, Lucienne Cooper, Sefina Arif, Stephen J. Mather, Joyce Taylor-Papadimitriou, Joy M. Burchell, and John Maher
J Immunol 2008 180: 4901-4909. [Abstract] [Full Text] [PDF]  

MDA5 Participates in the Detection of Paramyxovirus Infection and Is Essential for the Early Activation of Dendritic Cells in Response to Sendai Virus Defective Interfering Particles

Jacob S. Yount, Leonid Gitlin, Thomas M. Moran, and Carolina B. López
J Immunol 2008 180: 4910-4918. [Abstract] [Full Text] [PDF]  

CD209⁺ Macrophages Mediate Host Defense against Propionibacterium acnes

Philip T. Liu, Jenny Phan, Dominic Tang, Melissa Kanchanapoomi, Brian Hall, Stephan R. Krutzik, and Jenny Kim
J Immunol 2008 180: 4919-4923. [Abstract] [Full Text] [PDF]  

Maturation of Paneth Cells Induces the Refractory State of Newborn Mice to Shigella Infection

Maria-Isabel Fernandez, Béatrice Regnault, Céline Mulet, Myriam Tanguy, Philippe Jay, Philippe J. Sansonetti, and Thierry Pédron
J Immunol 2008 180: 4924-4930. [Abstract] [Full Text] [PDF]  

Adenoviral Expression of Suppressor of Cytokine Signaling-1 Reduces Adenovirus Vector-Induced Innate Immune Responses

Haruna Sakurai, Katsuhisa Tashiro, Kenji Kawabata, Tomoko Yamaguchi, Fuminori Sakurai, Shinsaku Nakagawa, and Hiroyuki Mizuguchi
J Immunol 2008 180: 4931-4938. [Abstract] [Full Text] [PDF]  

IL-13 Attenuates Gastrointestinal Candidiasis in Normal and Immunodeficient RAG-2^–/– Mice via Peroxisome Proliferator-Activated Receptor- Activation

Agnès Coste, Céline Lagane, Cédric Filipe, Hélène Authier, Amandine Galès, José Bernad, Victorine Douin-Echinard, Jean-Claude Lepert, Patricia Balard, Marie-Denise Linas, Jean-François Arnal, Johan Auwerx, and Bernard Pipy
J Immunol 2008 180: 4939-4947. [Abstract] [Full Text] [PDF]  

IL-4R Expression by Bone Marrow-Derived Cells Is Necessary and Sufficient for Host Protection against Acute Schistosomiasis

De’Broski R. Herbert, Tatyana Orekov, Charles Perkins, Marc E. Rothenberg, and Fred D. Finkelman
J Immunol 2008 180: 4948-4955. [Abstract] [Full Text] [PDF]  

Protection against Influenza A Virus by Memory CD8 T Cells Requires Reactivation by Bone Marrow-Derived Dendritic Cells

Paola Castiglioni, De Shon Hall, Erica L. Jacovetty, Elizabeth Ingulli, and Maurizio Zanetti
J Immunol 2008 180: 4956-4964. [Abstract] [Full Text] [PDF]  

Differential Initiation of Innate Immune Responses Induced by Human Cytomegalovirus Entry into Fibroblast Cells

Laura K. Juckem, Karl W. Boehme, Adam L. Feire, and Teresa Compton
J Immunol 2008 180: 4965-4977. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Apoptotic Cells Protect Mice against Lipopolysaccharide-Induced Shock

Yi Ren, Yi Xie, Guoping Jiang, Jianqing Fan, Joseph Yeung, Wen Li, Paul K. H. Tam, and John Savill
J Immunol 2008 180: 4978-4985. [Abstract] [Full Text] [PDF]  

TLR2 Regulates Gap Junction Intercellular Communication in Airway Cells

Francis J. Martin and Alice S. Prince
J Immunol 2008 180: 4986-4993. [Abstract] [Full Text] [PDF] Data Supplement  

Suppression of Proteoglycan-Induced Arthritis by Anti-CD20 B Cell Depletion Therapy Is Mediated by Reduction in Autoantibodies and CD4⁺ T Cell Reactivity

Keith Hamel, Paul Doodes, Yanxia Cao, Yumei Wang, Jeffrey Martinson, Robert Dunn, Marilyn R. Kehry, Balint Farkas, and Alison Finnegan
J Immunol 2008 180: 4994-5003. [Abstract] [Full Text] [PDF]  

The Synthetic Peroxisome Proliferator-Activated Receptor- Agonist Ciglitazone Attenuates Neuroinflammation and Accelerates Encapsulation in Bacterial Brain Abscesses

Tammy Kielian, Mohsin Md. Syed, Shuliang Liu, Nirmal K. Phulwani, Napoleon Phillips, Gail Wagoner, Paul D. Drew, and Nilufer Esen
J Immunol 2008 180: 5004-5016. [Abstract] [Full Text] [PDF]  

Molecular Characterization of Helicobacter pylori VacA Induction of IL-8 in U937 Cells Reveals a Prominent Role for p38MAPK in Activating Transcription Factor-2, cAMP Response Element Binding Protein, and NF-B Activation

Junzo Hisatsune, Masaaki Nakayama, Hajime Isomoto, Hisao Kurazono, Naofumi Mukaida, Asish K. Mukhopadhyay, Takeshi Azuma, Yoshio Yamaoka, Jan Sap, Eiki Yamasaki, Kinnosuke Yahiro, Joel Moss, and Toshiya Hirayama
J Immunol 2008 180: 5017-5027. [Abstract] [Full Text] [PDF]  

Phosphatidylinositol 3-Kinase and Xanthine Oxidase Regulate Nitric Oxide and Reactive Oxygen Species Productions by Apoptotic Lymphocyte Microparticles in Endothelial Cells

H. Ahmed Mostefai, Abdelali Agouni, Nunzia Carusio, M. Letizia Mastronardi, Christophe Heymes, Daniel Henrion, Ramaroson Andriantsitohaina, and M. Carmen Martinez
J Immunol 2008 180: 5028-5035. [Abstract] [Full Text] [PDF]  

Macrophages Produce TGF-β-Induced (β-ig-h3) following Ingestion of Apoptotic Cells and Regulate MMP14 Levels and Collagen Turnover in Fibroblasts

Natalia Nacu, Irina G. Luzina, Kendrick Highsmith, Virginia Lockatell, Kerill Pochetuhen, Zachary A. Cooper, Michael P. Gillmeister, Nevins W. Todd, and Sergei P. Atamas
J Immunol 2008 180: 5036-5044. [Abstract] [Full Text] [PDF]  

Salmonella Secreted Factor L Deubiquitinase of Salmonella typhimurium Inhibits NF-B, Suppresses IB Ubiquitination and Modulates Innate Immune Responses

Gaëlle Le Negrate, Benjamin Faustin, Kate Welsh, Markus Loeffler, Maryla Krajewska, Patty Hasegawa, Sohini Mukherjee, Kim Orth, Stan Krajewski, Adam Godzik, Donald G. Guiney, and John C. Reed
J Immunol 2008 180: 5045-5056. [Abstract] [Full Text] [PDF]  

Complement Receptors 1 and 2 Influence the Immune Environment in a B Cell Receptor-Independent Manner

Amanda C. Jacobson, Janis J. Weis, and John H. Weis
J Immunol 2008 180: 5057-5066. [Abstract] [Full Text] [PDF] Data Supplement  

High Mobility Group Box 1 Protein Binding to Lipopolysaccharide Facilitates Transfer of Lipopolysaccharide to CD14 and Enhances Lipopolysaccharide-Mediated TNF- Production in Human Monocytes

Ju Ho Youn, Young Joo Oh, Eun Sook Kim, Ji Eun Choi, and Jeon-Soo Shin
J Immunol 2008 180: 5067-5074. [Abstract] [Full Text] [PDF]  

Macrophage Deletion of p38 Partially Impairs Lipopolysaccharide-Induced Cellular Activation

Young Jun Kang, Jianming Chen, Motoyuki Otsuka, Johann Mols, Shuxun Ren, Yinbin Wang, and Jiahuai Han
J Immunol 2008 180: 5075-5082. [Abstract] [Full Text] [PDF]  

Destructive Arthritis in the Absence of Both FcRI and FcRIII

Peter Boross, Peter L. van Lent, Javier Martin-Ramirez, Jos van der Kaa, Melissa H. C. M. Mulder, Jill W. C. Claassens, Wim B. van den Berg, Victoria L. Arandhara, and J. Sjef Verbeek
J Immunol 2008 180: 5083-5091. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes

Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson
J Immunol 2008 180: 5092-5100. [Abstract] [Full Text] [PDF] Data Supplement  

A Novel Type I IFN-Producing Cell Subset in Murine Lupus

Pui Y. Lee, Jason S. Weinstein, Dina C. Nacionales, Philip O. Scumpia, Yi Li, Edward Butfiloski, Nico van Rooijen, Lyle Moldawer, Minoru Satoh, and Westley H. Reeves
J Immunol 2008 180: 5101-5108. [Abstract] [Full Text] [PDF]  

Human CD4⁺ T Cells Recognize an Epitope within -Fetoprotein Sequence and Develop into TGF-β-Producing CD4⁺ T Cells

Akeel Alisa, Sandra Boswell, Ansar A. Pathan, Lakshmana Ayaru, Roger Williams, and Shahriar Behboudi
J Immunol 2008 180: 5109-5117. [Abstract] [Full Text] [PDF]  

IL-2/Anti-IL-2 Antibody Complex Enhances Vaccine-Mediated Antigen-Specific CD8⁺ T Cell Responses and Increases the Ratio of Effector/Memory CD8⁺ T Cells to Regulatory T Cells

Sven Mostböck, M. E. Christine Lutsiak, Diane E. Milenic, Kwamena Baidoo, Jeffrey Schlom, and Helen Sabzevari
J Immunol 2008 180: 5118-5129. [Abstract] [Full Text] [PDF]  

CXCL13, CCL21, and CXCL12 Expression in Salivary Glands of Patients with Sjögren’s Syndrome and MALT Lymphoma: Association with Reactive and Malignant Areas of Lymphoid Organization

Francesca Barone, Michele Bombardieri, Manuela Maria Rosado, Peter Roger Morgan, Stephen J. Challacombe, Salvatore De Vita, Rita Carsetti, Jo Spencer, Guido Valesini, and Costantino Pitzalis
J Immunol 2008 180: 5130-5140. [Abstract] [Full Text] [PDF]  

The Presence of Activated CD4⁺ T Cells Is Essential for the Formation of Colony-Forming Unit-Endothelial Cells by CD14⁺ Cells

Rachel T. van Beem, Willy A. Noort, Carlijn Voermans, Marion Kleijer, Anja ten Brinke, S. Marieke van Ham, C. Ellen van der Schoot, and Jaap Jan Zwaginga
J Immunol 2008 180: 5141-5148. [Abstract] [Full Text] [PDF]  

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