IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2008 180: 3623-3624. [Full Text] [PDF]  

LETTERS TO THE EDITOR:

Comment on "MHC Class II Expression Identifies Functionally Distinct Human Regulatory T Cells"

Magdalena Swiatek-de Lange, Wolfgang Rist, Heiko F. Stahl, Andreas Weith, and Martin C. Lenter
J Immunol 2008 180: 3625. [Full Text] [PDF]  

Response to Comment on "MHC Class II Expression Identifies Functionally Distinct Human Regulatory T Cells"

Clare Baecher-Allan and David A. Hafler
J Immunol 2008 180: 3626. [Full Text] [PDF]  

BRIEF REVIEWS:

NKT Cells in Tumor Immunity: Opposing Subsets Define a New Immunoregulatory Axis

Jay A. Berzofsky and Masaki Terabe
J Immunol 2008 180: 3627-3635. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Programmed Death-1 Expression Is Increased on Immunocytes in Chronic Hepatitis C Virus and Predicts Failure of Response to Antiviral Therapy: Race-Dependent Differences

Lucy Golden-Mason, Jared Klarquist, Abdus S. Wahed, and Hugo R. Rosen
J Immunol 2008 180: 3637-3641. [Abstract] [Full Text] [PDF]  

Cutting Edge: A Naturally Occurring Mutation in CD1e Impairs Lipid Antigen Presentation

Sylvie Tourne, Blandine Maitre, Anthony Collmann, Emilie Layre, Sabrina Mariotti, François Signorino-Gelo, Caroline Loch, Jean Salamero, Martine Gilleron, Catherine Angénieux, Jean-Pierre Cazenave, Lucia Mori, Daniel Hanau, Germain Puzo, Gennaro De Libero, and Henri de la Salle
J Immunol 2008 180: 3642-3646. [Abstract] [Full Text] [PDF]  

Cutting Edge: Langerin/CD207 Receptor on Dendritic Cells Mediates Efficient Antigen Presentation on MHC I and II Products In Vivo

Juliana Idoyaga, Cheolho Cheong, Koji Suda, Nao Suda, Jae Y. Kim, Haekyung Lee, Chae Gyu Park, and Ralph M. Steinman
J Immunol 2008 180: 3647-3650. [Abstract] [Full Text] [PDF]  

Cutting Edge: Human CD4^–CD8^– Thymocytes Express FOXP3 in the Absence of a TCR

Heli Tuovinen, Eliisa Kekäläinen, Laura H. Rossi, Juha Puntila, and T. Petteri Arstila
J Immunol 2008 180: 3651-3654. [Abstract] [Full Text] [PDF]  

Cutting Edge: The Dependence of Plasma Cells and Independence of Memory B Cells on BAFF and APRIL

Micah J. Benson, Stacey R. Dillon, Emanuela Castigli, Raif S. Geha, Shengli Xu, Kong-Peng Lam, and Randolph J. Noelle
J Immunol 2008 180: 3655-3659. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Estrogen Receptor , but Not β, Is Required for Optimal Dendritic Cell Differentiation and CD40-Induced Cytokine Production

Victorine Douin-Echinard, Sophie Laffont, Cyril Seillet, Laurent Delpy, Andrée Krust, Pierre Chambon, Pierre Gourdy, Jean-François Arnal, and Jean-Charles Guéry
J Immunol 2008 180: 3661-3669. [Abstract] [Full Text] [PDF]  

Morphine Withdrawal Inhibits IL-12 Induction in a Macrophage Cell Line through a Mechanism That Involves cAMP

Jennifer Kelschenbach, Jana Ninkovic, Jinghua Wang, Anitha Krishnan, Richard Charboneau, Roderick A. Barke, and Sabita Roy
J Immunol 2008 180: 3670-3679. [Abstract] [Full Text] [PDF]  

Monocyte Cell Surface Glycosaminoglycans Positively Modulate IL-4-Induced Differentiation toward Dendritic Cells

Els den Dekker, Sander Grefte, Tonnie Huijs, Gerdy B. ten Dam, Elly M. M. Versteeg, Lieke C. J. van den Berk, Bellinda A. Bladergroen, Toin H. van Kuppevelt, Carl G. Figdor, and Ruurd Torensma
J Immunol 2008 180: 3680-3688. [Abstract] [Full Text] [PDF]  

Non-T Cell Activation Linker Promotes Mast Cell Survival by Dampening the Recruitment of SHIP1 by Linker for Activation of T Cells

Karine Roget, Marie Malissen, Odile Malbec, Bernard Malissen, and Marc Daëron
J Immunol 2008 180: 3689-3698. [Abstract] [Full Text] [PDF]  

E2F4 Modulates Differentiation and Gene Expression in Hematopoietic Progenitor Cells during Commitment to the Lymphoid Lineage

Megan E. Enos, Simona A. Bancos, Timothy Bushnell, and Ian N. Crispe
J Immunol 2008 180: 3699-3707. [Abstract] [Full Text] [PDF]  

Allelic and Isotypic Light Chain Inclusion in Peripheral B Cells from Anti-DNA Antibody Transgenic C57BL/6 and BALB/c Mice

Esther J. Witsch and Eldad Bettelheim
J Immunol 2008 180: 3708-3718. [Abstract] [Full Text] [PDF] Data Supplement  

The Use of Filamentous Bacteriophage fd to Deliver MAGE-A10 or MAGE-A3 HLA-A2-Restricted Peptides and to Induce Strong Antitumor CTL Responses

Rossella Sartorius, Paola Pisu, Luciana D’Apice, Luciano Pizzella, Chiara Romano, Giancarlo Cortese, Angela Giorgini, Angela Santoni, Francesca Velotti, and Piergiuseppe De Berardinis
J Immunol 2008 180: 3719-3728. [Abstract] [Full Text] [PDF]  

Identification of RNA Sequence Motifs Stimulating Sequence-Specific TLR8-Dependent Immune Responses

Alexandra Forsbach, Jean-Guy Nemorin, Carmen Montino, Christian Müller, Ulrike Samulowitz, Alain P. Vicari, Marion Jurk, George K. Mutwiri, Arthur M. Krieg, Grayson B. Lipford, and Jörg Vollmer
J Immunol 2008 180: 3729-3738. [Abstract] [Full Text] [PDF]  

CD27 Defines Phenotypically and Functionally Different Human NK Cell Subsets

Mireille T. M. Vossen, Mourad Matmati, Kirsten M. L. Hertoghs, Paul A. Baars, Mi-Ran Gent, Georges Leclercq, Jörg Hamann, Taco W. Kuijpers, and René A. W. van Lier
J Immunol 2008 180: 3739-3745. [Abstract] [Full Text] [PDF]  

Loss of Suppressor of Cytokine Signaling 1 in Helper T Cells Leads to Defective Th17 Differentiation by Enhancing Antagonistic Effects of IFN- on STAT3 and Smads

Kentaro Tanaka, Kenji Ichiyama, Masayuki Hashimoto, Hideyuki Yoshida, Tomohito Takimoto, Giichi Takaesu, Takehiro Torisu, Toshikatsu Hanada, Hideo Yasukawa, Satoru Fukuyama, Hiromasa Inoue, Yoichi Nakanishi, Takashi Kobayashi, and Akihiko Yoshimura
J Immunol 2008 180: 3746-3756. [Abstract] [Full Text] [PDF]  

IL-15 Does Not Affect IEL Development in the Thymus but Regulates Homeostasis of Putative Precursors and Mature CD8⁺ IELs in the Intestine

Yein-Gei Lai, Mau-Sheng Hou, Yaw-Wen Hsu, Chin-Ling Chang, Yae-Huei Liou, Ming-Han Tsai, Fan Lee, and Nan-Shih Liao
J Immunol 2008 180: 3757-3765. [Abstract] [Full Text] [PDF]  

Modulation of the Tumor Cell Phenotype by IFN- Results in Resistance of Uveal Melanoma Cells to Granule-Mediated Lysis by Cytotoxic Lymphocytes

Kristian Hallermalm, Kazutake Seki, Anna De Geer, Bruce Motyka, R. Chris Bleackley, Martine J. Jager, Christopher J. Froelich, Rolf Kiessling, Victor Levitsky, and Jelena Levitskaya
J Immunol 2008 180: 3766-3774. [Abstract] [Full Text] [PDF]  

Telomerase Is Involved in IL-7-Mediated Differential Survival of Naive and Memory CD4⁺ T Cells

Yinhua Yang, Jie An, and Nan-ping Weng
J Immunol 2008 180: 3775-3781. [Abstract] [Full Text] [PDF]  

Human Lymphocyte Activation Gene-3 Molecules Expressed by Activated T Cells Deliver Costimulation Signal for Dendritic Cell Activation

Chiara Casati, Chiara Camisaschi, Luisa Novellino, Arabella Mazzocchi, Frédéric Triebel, Licia Rivoltini, Giorgio Parmiani, and Chiara Castelli
J Immunol 2008 180: 3782-3788. [Abstract] [Full Text] [PDF]  

IFN-β Provides Immuno-Protection in the Retina by Inhibiting ICAM-1 and CXCL9 in Retinal Pigment Epithelial Cells

John J. Hooks, Chandrasekharam N. Nagineni, Laura C. Hooper, Kozaburo Hayashi, and Barbara Detrick
J Immunol 2008 180: 3789-3796. [Abstract] [Full Text] [PDF]  

Attenuating Regulatory T Cell Induction by TLR Agonists through Inhibition of p38 MAPK Signaling in Dendritic Cells Enhances Their Efficacy as Vaccine Adjuvants and Cancer Immunotherapeutics

Andrew G. Jarnicki, Helen Conroy, Corinna Brereton, Graham Donnelly, Deirdre Toomey, Kevin Walsh, Cheryl Sweeney, Olive Leavy, Jean Fletcher, Ed C. Lavelle, Padraic Dunne, and Kingston H. G. Mills
J Immunol 2008 180: 3797-3806. [Abstract] [Full Text] [PDF]  

A Lupus-Suppressor BALB/c Locus Restricts IgG2 Autoantibodies without Altering Intrinsic B Cell-Tolerance Mechanisms

Tatyana Tarasenko, Hemanta K. Kole, and Silvia Bolland
J Immunol 2008 180: 3807-3814. [Abstract] [Full Text] [PDF]  

A Novel B7-2 (CD86) Splice Variant with a Putative Negative Regulatory Role

Efstathia K. Kapsogeorgou, Haralampos M. Moutsopoulos, and Menelaos N. Manoussakis
J Immunol 2008 180: 3815-3823. [Abstract] [Full Text] [PDF]  

A Specific Anti-Aire Antibody Reveals Aire Expression Is Restricted to Medullary Thymic Epithelial Cells and Not Expressed in Periphery

François-Xavier Hubert, Sarah A. Kinkel, Kylie E. Webster, Ping Cannon, Pauline E. Crewther, Anna I. Proeitto, Li Wu, William R. Heath, and Hamish S. Scott
J Immunol 2008 180: 3824-3832. [Abstract] [Full Text] [PDF]  

Differential Sensitivity to Itk Kinase Signals for T Helper 2 Cytokine Production and Chemokine-Mediated Migration

Nisebita Sahu, Cynthia Mueller, Angela Fischer, and Avery August
J Immunol 2008 180: 3833-3838. [Abstract] [Full Text] [PDF]  

Ig Knock-In Mice Producing Anti-Carbohydrate Antibodies: Breakthrough of B Cells Producing Low Affinity Anti-Self Antibodies

Lorenzo Benatuil, Joel Kaye, Nathalie Cretin, Jonathan G. Godwin, Annaiah Cariappa, Shiv Pillai, and John Iacomini
J Immunol 2008 180: 3839-3848. [Abstract] [Full Text] [PDF]  

First Signature of Islet β-Cell-Derived Naturally Processed Peptides Selected by Diabetogenic Class II MHC Molecules

Anish Suri, James J. Walters, Henry W. Rohrs, Michael L. Gross, and Emil R. Unanue
J Immunol 2008 180: 3849-3856. [Abstract] [Full Text] [PDF]  

Memory CD8⁺ T Cells Protect Dendritic Cells from CTL Killing

Payal B. Watchmaker, Julie A. Urban, Erik Berk, Yutaro Nakamura, Robbie B. Mailliard, Simon C. Watkins, S. Marieke van Ham, and Pawel Kalinski
J Immunol 2008 180: 3857-3865. [Abstract] [Full Text] [PDF]  

Neuroprotective Immunity: T Cell-Derived Glutamate Endows Astrocytes with a Neuroprotective Phenotype

Sanjay K. Garg, Ruma Banerjee, and Jonathan Kipnis
J Immunol 2008 180: 3866-3873. [Abstract] [Full Text] [PDF]  

Intestinal Epithelial Cell Up-Regulation of LY6 Molecules during Colitis Results in Enhanced Chemokine Secretion

Ken Flanagan, Zora Modrusan, Jennine Cornelius, Arvind Chavali, Ian Kasman, Laszlo Komuves, Lian Mo, and Lauri Diehl
J Immunol 2008 180: 3874-3881. [Abstract] [Full Text] [PDF]  

TLR Agonists Promote Marginal Zone B Cell Activation and Facilitate T-Dependent IgM Responses

Anatoly V. Rubtsov, Cristina L. Swanson, Scott Troy, Pamela Strauch, Roberta Pelanda, and Raul M. Torres
J Immunol 2008 180: 3882-3888. [Abstract] [Full Text] [PDF]  

Lipopolysaccharide-Activated IL-10-Secreting Dendritic Cells Suppress Experimental Autoimmune Uveoretinitis by MHCII-Dependent Activation of CD62L-Expressing Regulatory T Cells

Annie W. T. Lau, Sabine Biester, Richard J. Cornall, and John V. Forrester
J Immunol 2008 180: 3889-3899. [Abstract] [Full Text] [PDF]  

A Role for CD8 in the Developmental Tuning of Antigen Recognition and CD3 Conformational Change

Diana Gil, Adam G. Schrum, Mark A. Daniels, and Ed Palmer
J Immunol 2008 180: 3900-3909. [Abstract] [Full Text] [PDF]  

Homeostatic Proliferation of Lymphocytes Results in Augmented Memory-Like Function and Accelerated Allograft Rejection

Victoria F. Moxham, Julieta Karegli, Richard E. Phillips, Kathryn L. Brown, Thomas T. Tapmeier, Robert Hangartner, Steven H. Sacks, and Wilson Wong
J Immunol 2008 180: 3910-3918. [Abstract] [Full Text] [PDF]  

Postnatal Life Events Affect the Severity of Asthmatic Airway Inflammation in the Adult Rat

Carsten Kruschinski, Thomas Skripuletz, Sammy Bedoui, Kerstin Raber, Rainer H. Straub, Torsten Hoffmann, Karsten Grote, Roland Jacobs, Michael Stephan, Reinhard Pabst, and Stephan von Hörsten
J Immunol 2008 180: 3919-3925. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Structural and Biological Basis of CTL Escape in Coronavirus-Infected Mice

Noah S. Butler, Alex Theodossis, Andrew I. Webb, Michelle A. Dunstone, Roza Nastovska, Sri Harsha Ramarathinam, Jamie Rossjohn, Anthony W. Purcell, and Stanley Perlman
J Immunol 2008 180: 3926-3937. [Abstract] [Full Text] [PDF]  

Filamin A Stabilizes FcRI Surface Expression and Prevents Its Lysosomal Routing

Jeffrey M. Beekman, Cees E. van der Poel, Joke A. van der Linden, Debbie L. C. van den Berg, Peter V. E. van den Berghe, Jan G. J. van de Winkel, and Jeanette H. W. Leusen
J Immunol 2008 180: 3938-3945. [Abstract] [Full Text] [PDF]  

Structural Insight into the Function of Myelin Basic Protein as a Ligand for Integrin _Mβ₂

Romualdas Stapulionis, Cristiano Luis Pinto Oliveira, Mikkel Carstensen Gjelstrup, Jan Skov Pedersen, Marianne Elisabet Hokland, Søren Vrønning Hoffmann, Knud Poulsen, Christian Jacobsen, and Thomas Vorup-Jensen
J Immunol 2008 180: 3946-3956. [Abstract] [Full Text] [PDF]  

Autoantibody Profiling in Multiple Sclerosis Reveals Novel Antigenic Candidates

Veerle Somers, Cindy Govarts, Klaartje Somers, Raymond Hupperts, Rob Medaer, and Piet Stinissen
J Immunol 2008 180: 3957-3963. [Abstract] [Full Text] [PDF]  

A Novel Mechanism of Complement Inhibition Unmasked by a Tick Salivary Protein That Binds to Properdin

Katharine R. Tyson, Christopher Elkins, and Aravinda M. de Silva
J Immunol 2008 180: 3964-3968. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Synergistic Polymorphism at Two Positions Distal to the Ligand-Binding Site Makes KIR2DL2 a Stronger Receptor for HLA-C Than KIR2DL3

Achim K. Moesta, Paul J. Norman, Makoto Yawata, Nobuyo Yawata, Michael Gleimer, and Peter Parham
J Immunol 2008 180: 3969-3979. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Functional Maturation of the Human Antibody Response to Rotavirus

Nicole L. Kallewaard, Brett A. McKinney, Yingqi Gu, Annie Chen, B. V. Venkataram Prasad, and James E. Crowe, Jr.
J Immunol 2008 180: 3980-3989. [Abstract] [Full Text] [PDF]  

Sporozoite-Mediated Hepatocyte Wounding Limits Plasmodium Parasite Development via MyD88-Mediated NF-B Activation and Inducible NO Synthase Expression

Ralph Torgler, Silayuv E. Bongfen, Jackeline C. Romero, Aubry Tardivel, Margot Thome, and Giampietro Corradin
J Immunol 2008 180: 3990-3999. [Abstract] [Full Text] [PDF]  

Suppression of an Already Established Tumor Growing through Activated Mucosal CTLs Induced by Oral Administration of Tumor Antigen with Cholera Toxin

Ayako Wakabayashi, Yohko Nakagawa, Masumi Shimizu, Keiichi Moriya, Yasuhiro Nishiyama, and Hidemi Takahashi
J Immunol 2008 180: 4000-4010. [Abstract] [Full Text] [PDF]  

Identification of an N-Linked Glycosylation in the C4 Region of HIV-1 Envelope gp120 That Is Critical for Recognition of Neighboring CD4 T Cell Epitopes

Hualin Li, Peter C. Chien, Jr., Michael Tuen, Maria Luisa Visciano, Sandra Cohen, Steven Blais, Chong-Feng Xu, Hui-Tang Zhang, and Catarina E. Hioe
J Immunol 2008 180: 4011-4021. [Abstract] [Full Text] [PDF]  

Lack of Toll IL-1R8 Exacerbates Th17 Cell Responses in Fungal Infection

Silvia Bozza, Teresa Zelante, Silvia Moretti, Pierluigi Bonifazi, Antonella DeLuca, Carmen D’Angelo, Gloria Giovannini, Cecilia Garlanda, Louis Boon, Francesco Bistoni, Paolo Puccetti, Alberto Mantovani, and Luigina Romani
J Immunol 2008 180: 4022-4031. [Abstract] [Full Text] [PDF]  

Potent Antimycobacterial Activity of Mouse Secretory Leukocyte Protease Inhibitor

Junichi Nishimura, Hiroyuki Saiga, Shintaro Sato, Megumi Okuyama, Hisako Kayama, Hirotaka Kuwata, Sohkichi Matsumoto, Toshirou Nishida, Yoshiki Sawa, Shizuo Akira, Yasunobu Yoshikai, Masahiro Yamamoto, and Kiyoshi Takeda
J Immunol 2008 180: 4032-4039. [Abstract] [Full Text] [PDF]  

SOCS-1 Protects against Chlamydia pneumoniae-Induced Lethal Inflammation but Hampers Effective Bacterial Clearance

Tangbin Yang, Patrik Stark, Katrin Janik, Hans Wigzell, and Martin E. Rottenberg
J Immunol 2008 180: 4040-4049. [Abstract] [Full Text] [PDF]  

Pannexin-1-Mediated Intracellular Delivery of Muramyl Dipeptide Induces Caspase-1 Activation via Cryopyrin/NLRP3 Independently of Nod2

Noemí Marina-García, Luigi Franchi, Yun-Gi Kim, Douglas Miller, Christine McDonald, Geert-Jan Boons, and Gabriel Núñez
J Immunol 2008 180: 4050-4057. [Abstract] [Full Text] [PDF]  

Functional CD8⁺ T Cell Responses in Lethal Ebola Virus Infection

Steven B. Bradfute, Kelly L. Warfield, and Sina Bavari
J Immunol 2008 180: 4058-4066. [Abstract] [Full Text] [PDF]  

Deoxynucleic Acids from Cryptococcus neoformans Activate Myeloid Dendritic Cells via a TLR9-Dependent Pathway

Kiwamu Nakamura, Akiko Miyazato, Gang Xiao, Masumitsu Hatta, Ken Inden, Tetsuji Aoyagi, Kohei Shiratori, Kiyoshi Takeda, Shizuo Akira, Shinobu Saijo, Yoichiro Iwakura, Yoshiyuki Adachi, Naohito Ohno, Kazuo Suzuki, Jiro Fujita, Mitsuo Kaku, and Kazuyoshi Kawakami
J Immunol 2008 180: 4067-4074. [Abstract] [Full Text] [PDF]  

Functional Adaptation of Nef to the Immune Milieu of HIV-1 Infection In Vivo

Martha J. Lewis, Arumugam Balamurugan, Ayako Ohno, Stephanie Kilpatrick, Hwee L. Ng, and Otto O. Yang
J Immunol 2008 180: 4075-4081. [Abstract] [Full Text] [PDF]  

Activation of Human NK Cells by the Bacterial Pathogen-Associated Molecular Pattern Muramyl Dipeptide

Verónica Athié-Morales, Geraldine M. O’Connor, and Clair M. Gardiner
J Immunol 2008 180: 4082-4089. [Abstract] [Full Text] [PDF]  

IL-10 and TGF-β Control the Establishment of Persistent and Transmissible Infections Produced by Leishmania tropica in C57BL/6 Mice

Charles F. Anderson, Rosalia Lira, Shaden Kamhawi, Yasmine Belkaid, Thomas A. Wynn, and David Sacks
J Immunol 2008 180: 4090-4097. [Abstract] [Full Text] [PDF]  

Characterization of Pulmonary T Cell Response to Helper-Dependent Adenoviral Vectors following Intranasal Delivery

Rahul Kushwah, Huibi Cao, and Jim Hu
J Immunol 2008 180: 4098-4108. [Abstract] [Full Text] [PDF]  

Deviation from a Strong Th1-Dominated to a Modest Th17-Dominated CD4 T Cell Response in the Absence of IL-12p40 and Type I IFNs Sustains Protective CD8 T Cells

Nural N. Orgun, Meredith A. Mathis, Christopher B. Wilson, and Sing Sing Way
J Immunol 2008 180: 4109-4115. [Abstract] [Full Text] [PDF]  

IFN-β Increases Listeriolysin O-Induced Membrane Permeabilization and Death of Macrophages

Heather Zwaferink, Silvia Stockinger, Parastoo Hazemi, Rosa Lemmens-Gruber, and Thomas Decker
J Immunol 2008 180: 4116-4123. [Abstract] [Full Text] [PDF]  

Mannose-Binding Lectin (MBL) Facilitates Opsonophagocytosis of Yeasts but Not of Bacteria despite MBL Binding

Nannette Brouwer, Koert M. Dolman, Michel van Houdt, Marleen Sta, Dirk Roos, and Taco W. Kuijpers
J Immunol 2008 180: 4124-4132. [Abstract] [Full Text] [PDF]  

Role of Polymorphonuclear Neutrophils on Infectious Complications Stemming from Enterococcus faecalis Oral Infection in Thermally Injured Mice

Yasuhiro Tsuda, Kenji Shigematsu, Makiko Kobayashi, David N. Herndon, and Fujio Suzuki
J Immunol 2008 180: 4133-4138. [Abstract] [Full Text] [PDF]  

Anthrax Lethal Toxin Increases Superoxide Production in Murine Neutrophils via Differential Effects on MAPK Signaling Pathways

Lixin Xu, Hui Fang, and David M. Frucht
J Immunol 2008 180: 4139-4147. [Abstract] [Full Text] [PDF]  

Endogenous IFN- Production Is Induced and Required for Protective Immunity against Pulmonary Chlamydial Infection in Neonatal Mice

Madhulika Jupelli, M. Neal Guentzel, Patricia A. Meier, Guangming Zhong, Ashlesh K. Murthy, and Bernard P. Arulanandam
J Immunol 2008 180: 4148-4155. [Abstract] [Full Text] [PDF]  

Spleen Size Predicts Resistance of Rainbow Trout to Flavobacterium psychrophilum Challenge

Sima Hadidi, Gavin W. Glenney, Timothy J. Welch, Jeffrey T. Silverstein, and Gregory D. Wiens
J Immunol 2008 180: 4156-4165. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

ERK5/BMK1 Is Indispensable for Optimal Colony-Stimulating Factor 1 (CSF-1)-Induced Proliferation in Macrophages in a Src-Dependent Fashion

Elisabetta Rovida, Elena Spinelli, Sara Sdelci, Valentina Barbetti, Andrea Morandi, Serena Giuntoli, and Persio Dello Sbarba
J Immunol 2008 180: 4166-4172. [Abstract] [Full Text] [PDF]  

Adenosine Promotes IL-6 Release in Airway Epithelia

Ying Sun, Fan Wu, Fengqiang Sun, and Pingbo Huang
J Immunol 2008 180: 4173-4181. [Abstract] [Full Text] [PDF]  

Cross-Talk between ICAM-1 and GM-CSF Receptor Signaling Modulates Eosinophil Survival and Activation

Konrad Pazdrak, Travis W. Young, Susan Stafford, Barbara Olszewska-Pazdrak, Christof Straub, Vitaliy Starosta, Allan Brasier, and Alexander Kurosky
J Immunol 2008 180: 4182-4190. [Abstract] [Full Text] [PDF]  

Dual Modulation of Airway Smooth Muscle Contraction by Th2 Cytokines via Matrix Metalloproteinase-1 Production

Yoshinori Ohta, Masayuki Hayashi, Takaaki Kanemaru, Kihachiro Abe, Yushi Ito, and Masahiro Oike
J Immunol 2008 180: 4191-4199. [Abstract] [Full Text] [PDF]  

STAT-1 Signaling in Human Lung Fibroblasts Is Induced by Vanadium Pentoxide through an IFN-β Autocrine Loop

Aurita Antao-Menezes, Elizabeth A. Turpin, Phillip C. Bost, Jessica P. Ryman-Rasmussen, and James C. Bonner
J Immunol 2008 180: 4200-4207. [Abstract] [Full Text] [PDF]  

Induced Loss of Syk in Human Basophils by Non-IgE-Dependent Stimuli

Donald W. MacGlashan, Jr., Susan Ishmael, Susan M. MacDonald, Jacqueline M. Langdon, Jonathan P. Arm, and David E. Sloane
J Immunol 2008 180: 4208-4217. [Abstract] [Full Text] [PDF]  

Genetic Analysis of the Role of the PI3K-Akt Pathway in Lipopolysaccharide-Induced Cytokine and Tissue Factor Gene Expression in Monocytes/Macrophages

James P. Luyendyk, Gernot A. Schabbauer, Michael Tencati, Todd Holscher, Rafal Pawlinski, and Nigel Mackman
J Immunol 2008 180: 4218-4226. [Abstract] [Full Text] [PDF]  

Neuritogenic Effects of T Cell-Derived IL-3 on Mouse Splenic Sympathetic Neurons In Vivo

Yukiko Kannan-Hayashi, Kensaku Okamura, Shizuka Hattori, Mitsuru Kuwamura, Etsuko Higuchi, Hiroki Terayama, Mitsuaki Moriyama, Masafumi Mukamoto, Masaji Okada, Yoshiyuki Ohsugi, and Yoichi Nakamura
J Immunol 2008 180: 4227-4234. [Abstract] [Full Text] [PDF]  

CD44 Suppresses TLR-Mediated Inflammation

Hidetada Kawana, Hirokazu Karaki, Morihiro Higashi, Masaru Miyazaki, Frank Hilberg, Motoo Kitagawa, and Kenichi Harigaya
J Immunol 2008 180: 4235-4245. [Abstract] [Full Text] [PDF]  

Control of IFN-A by CD73: Implications for Mucosal Inflammation

Nancy A. Louis, Andreas M. Robinson, Christopher F. MacManus, Jörn Karhausen, Melanie Scully, and Sean P. Colgan
J Immunol 2008 180: 4246-4255. [Abstract] [Full Text] [PDF]  

A Phosphosite Screen Identifies Autocrine TGF-β-Driven Activation of Protein Kinase R as a Survival-Limiting Factor for Eosinophils

Nicholas Goplen, Magdalena M. Gorska, Susan J. Stafford, Sadee Rozario, Lei Guo, Qiaoling Liang, and Rafeul Alam
J Immunol 2008 180: 4256-4264. [Abstract] [Full Text] [PDF]  

A Helminth Immunomodulator Reduces Allergic and Inflammatory Responses by Induction of IL-10-Producing Macrophages

Corinna Schnoeller, Sebastian Rausch, Smitha Pillai, Angela Avagyan, Bianca M. Wittig, Christoph Loddenkemper, Alf Hamann, Eckard Hamelmann, Richard Lucius, and Susanne Hartmann
J Immunol 2008 180: 4265-4272. [Abstract] [Full Text] [PDF]  

A Critical Role for ABCG1 in Macrophage Inflammation and Lung Homeostasis

Allison J. Wojcik, Marcus D. Skaflen, Suseela Srinivasan, and Catherine C. Hedrick
J Immunol 2008 180: 4273-4282. [Abstract] [Full Text] [PDF]  

Protective Roles of the Fractalkine/CX3CL1-CX3CR1 Interactions in Alkali-Induced Corneal Neovascularization through Enhanced Antiangiogenic Factor Expression

Peirong Lu, Longbiao Li, Kouji Kuno, Yu Wu, Tomohisa Baba, Ying-yi Li, Xueguang Zhang, and Naofumi Mukaida
J Immunol 2008 180: 4283-4291. [Abstract] [Full Text] [PDF]  

Delivery of Biologically Active Anti-Inflammatory Cytokines IL-10 and IL-1ra In Vivo by the Shigella Type III Secretion Apparatus

Mustapha Chamekh, Armelle Phalipon, Renaud Quertainmont, Isabelle Salmon, Philippe Sansonetti, and Abdelmounaaïm Allaoui
J Immunol 2008 180: 4292-4298. [Abstract] [Full Text] [PDF]  

Hsp70 Translocates into the Plasma Membrane after Stress and Is Released into the Extracellular Environment in a Membrane-Associated Form that Activates Macrophages

Virginia L. Vega, Monica Rodríguez-Silva, Tiffany Frey, Mathias Gehrmann, Juan Carlos Diaz, Claudia Steinem, Gabriele Multhoff, Nelson Arispe, and Antonio De Maio
J Immunol 2008 180: 4299-4307. [Abstract] [Full Text] [PDF]  

Neutrophil Chemokines KC and Macrophage-Inflammatory Protein-2 Are Newly Synthesized by Tissue Macrophages Using Distinct TLR Signaling Pathways

Katia De Filippo, Robert B. Henderson, Melanie Laschinger, and Nancy Hogg
J Immunol 2008 180: 4308-4315. [Abstract] [Full Text] [PDF]  

C-Reactive Protein-Bound Enzymatically Modified Low-Density Lipoprotein Does Not Transform Macrophages into Foam Cells

Sanjay K. Singh, Madathilparambil V. Suresh, Deborah C. Prayther, Jonathan P. Moorman, Antonio E. Rusiñol, and Alok Agrawal
J Immunol 2008 180: 4316-4322. [Abstract] [Full Text] [PDF]  

The Role of Sphingosine Kinase in a Murine Model of Allergic Asthma

Wen-Qi Lai, Hong Heng Goh, Zhang Bao, W. S. Fred Wong, Alirio J. Melendez, and Bernard P. Leung
J Immunol 2008 180: 4323-4329. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Analysis of HLA-G in Maternal Plasma, Follicular Fluid, and Preimplantation Embryos Reveal an Asymmetric Pattern of Expression

Valerie R. Shaikly, Ian E. G. Morrison, Mohamed Taranissi, Clare V. Noble, Anna D. Withey, Richard J. Cherry, Sandra M. Blois, and Nelson Fernández
J Immunol 2008 180: 4330-4337. [Abstract] [Full Text] [PDF]  

Tumor Cell Killing Mechanisms of Epidermal Growth Factor Receptor (EGFR) Antibodies Are Not Affected by Lung Cancer-Associated EGFR Kinase Mutations

Matthias Peipp, Tanja Schneider-Merck, Michael Dechant, Thomas Beyer, Jeroen J. Lammerts van Bueren, Wim K. Bleeker, Paul W. H. I. Parren, Jan G. J. van de Winkel, and Thomas Valerius
J Immunol 2008 180: 4338-4345. [Abstract] [Full Text] [PDF]  

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