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On the cover: Up-regulation of tissue transglutaminase (TG2) protein and activity in human bronchial epithelial 16HBE cells after specific inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR). The merged image of confocal microscopy shows TG2 protein (green) and TG2 activity (blue). Merge is indicated by overlay of individual channels (cyan). Maiuri, L., A. Luciani, I. Giardin, V. Raia, V. R. Villella, M. D’Apolito, M. Pettoello-Mantovani, S. Guido, C. Ciacci, M. Cimmino, O. N. Cexus, M. Londei, and S. Quaratino. 2008. Tissue transglutaminase activation modulates inflammation in cystic fibrosis via PPARγ down-regulation. J. Immunol. 180: 7697–7705.