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On the cover: Rapid CD4 immunohistochemical stain of experimental type 2 lung granuloma elicited with Schistosoma mansoni egg antigen-coated agarose bead. Individual CD4+ cells from sites of synchronized granuloma formation are then harvested by laser capture microdissection for gene expression analysis. Freeman, C. M., V. R. Stolberg, B.-C. Chiu, N. W. Lukacs, S. L. Kunkel, and S. W. Chensue. 2006. CCR4 participation in Th type 1 (mycobacterial) and Th type 2 (schistosomal) anamnestic pulmonary granulomatous responses. J. Immunol. 177: 4149–4158.



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