IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2006 177: 7481-7482. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

A Nuclear Factor in B Cells and Beyond

Michael J. May
J Immunol 2006 177: 7483-7484. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Multiple Nuclear Factors Interact with the Immunoglobulin Enhancer Sequences. Cell 1986. 46: 705–716.

Ranjan Sen and David Baltimore
J Immunol 2006 177: 7485-7496. [PDF]  

BRIEF REVIEWS:

DUSP Meet Immunology: Dual Specificity MAPK Phosphatases in Control of the Inflammatory Response

Roland Lang, Michael Hammer, and Jörg Mages
J Immunol 2006 177: 7497-7504. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: TLR3 Stimulation Suppresses Experimental Autoimmune Encephalomyelitis by Inducing Endogenous IFN-

Tarik Touil, Denise Fitzgerald, Guang-Xian Zhang, Abdolmohamad Rostami, and Bruno Gran
J Immunol 2006 177: 7505-7509. [Abstract] [Full Text] [PDF]  

Cutting Edge: Plasmacytoid Dendritic Cells Provide Innate Immune Protection against Mucosal Viral Infection In Situ

Jennifer M. Lund, Melissa M. Linehan, Norifumi Iijima, and Akiko Iwasaki
J Immunol 2006 177: 7510-7514. [Abstract] [Full Text] [PDF]  

Cutting Edge: IL-12 Inversely Regulates T-bet and Eomesodermin Expression during Pathogen-Induced CD8⁺ T Cell Differentiation

Naofumi Takemoto, Andrew M. Intlekofer, John T. Northrup, E. John Wherry, and Steven L. Reiner
J Immunol 2006 177: 7515-7519. [Abstract] [Full Text] [PDF]  

Cutting Edge: Pivotal Function of Ubc13 in Thymocyte TCR Signaling

Masahiro Yamamoto, Shintaro Sato, Tatsuya Saitoh, Hiroaki Sakurai, Satoshi Uematsu, Taro Kawai, Ken J. Ishii, Osamu Takeuchi, and Shizuo Akira
J Immunol 2006 177: 7520-7524. [Abstract] [Full Text] [PDF]  

Cutting Edge: Stimulation of Dopamine D₄ Receptors Induce T Cell Quiescence by Up-Regulating Krüppel-Like Factor-2 Expression through Inhibition of ERK1/ERK2 Phosphorylation

Chandrani Sarkar, Shamik Das, Debanjan Chakroborty, Uttio Roy Chowdhury, Biswarup Basu, Partha Sarathi Dasgupta, and Sujit Basu
J Immunol 2006 177: 7525-7529. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

CCR4 Is a Key Modulator of Innate Immune Responses

Traci L. Ness, Jillian L. Ewing, Cory M. Hogaboam, and Steven L. Kunkel
J Immunol 2006 177: 7531-7539. [Abstract] [Full Text] [PDF]  

Cytotoxic T Lymphocytes Induce Caspase-Dependent and -Independent Cell Death in Neuroblastomas in a MHC-Nonrestricted Fashion

Anna De Geer, Rolf Kiessling, Victor Levitsky, and Jelena Levitskaya
J Immunol 2006 177: 7540-7550. [Abstract] [Full Text] [PDF]  

Macrophages and Myeloid Dendritic Cells, but Not Plasmacytoid Dendritic Cells, Produce IL-10 in Response to MyD88- and TRIF-Dependent TLR Signals, and TLR-Independent Signals

André Boonstra, Ricardo Rajsbaum, Mary Holman, Rute Marques, Carine Asselin-Paturel, João Pedro Pereira, Elizabeth E. M. Bates, Shizuo Akira, Paulo Vieira, Yong-Jun Liu, Giorgio Trinchieri, and Anne O’Garra
J Immunol 2006 177: 7551-7558. [Abstract] [Full Text] [PDF]  

A Novel E3 Ubiquitin Ligase Substrate Screen Identifies Rho Guanine Dissociation Inhibitor as a Substrate of Gene Related to Anergy in Lymphocytes

Leon Su, Neil Lineberry, Yul Huh, Luis Soares, and C. Garrison Fathman
J Immunol 2006 177: 7559-7566. [Abstract] [Full Text] [PDF]  

Paternal Antigen-Bearing Cells Transferred during Insemination Do Not Stimulate Anti-Paternal CD8⁺ T Cells: Role of Estradiol in Locally Inhibiting CD8⁺ T Cell Responses

Matthew M. Seavey and Tim R. Mosmann
J Immunol 2006 177: 7567-7578. [Abstract] [Full Text] [PDF]  

IL-27 Induces Th1 Differentiation via p38 MAPK/T-bet- and Intercellular Adhesion Molecule-1/LFA-1/ERK1/2-Dependent Pathways

Toshiyuki Owaki, Masayuki Asakawa, Fumio Fukai, Junichiro Mizuguchi, and Takayuki Yoshimoto
J Immunol 2006 177: 7579-7587. [Abstract] [Full Text] [PDF]  

Loss of Invariant Chain Protects Nonobese Diabetic Mice against Type 1 Diabetes

Richard J. Mellanby, Chad H. Koonce, Anthony Monti, Jenny M. Phillips, Anne Cooke, and Elizabeth K. Bikoff
J Immunol 2006 177: 7588-7598. [Abstract] [Full Text] [PDF]  

The Chemokine CX3CL1 Reduces Migration and Increases Adhesion of Neurons with Mechanisms Dependent on the ₁ Integrin Subunit

Clotilde Lauro, Myriam Catalano, Flavia Trettel, Fabrizio Mainiero, Maria Teresa Ciotti, Fabrizio Eusebi, and Cristina Limatola
J Immunol 2006 177: 7599-7606. [Abstract] [Full Text] [PDF]  

ERK5 Activates NF-B in Leukemic T Cells and Is Essential for Their Growth In Vivo

Johan Garaude, Seyma Cherni, Sandra Kaminski, Etienne Delepine, Christine Chable-Bessia, Monsef Benkirane, Joana Borges, Atanasio Pandiella, Miguel Angel Iñiguez, Manuel Fresno, Robert A. Hipskind, and Martin Villalba
J Immunol 2006 177: 7607-7617. [Abstract] [Full Text] [PDF]  

IL-12-Programmed Long-Term CD8⁺ T Cell Responses Require STAT4

Qingsheng Li, Cheryl Eppolito, Kunle Odunsi, and Protul A. Shrikant
J Immunol 2006 177: 7618-7625. [Abstract] [Full Text] [PDF]  

Distinct and Non-Overlapping T Cell Receptor Repertoires Expanded by DNA Vaccination in Wild-Type and HER-2 Transgenic BALB/c Mice

Simona Rolla, Chiara Nicoló, Silvia Malinarich, Massimiliano Orsini, Guido Forni, Federica Cavallo, and Francesco Ria
J Immunol 2006 177: 7626-7633. [Abstract] [Full Text] [PDF]  

Oral Tolerance Induction with Antigen Conjugated to Cholera Toxin B Subunit Generates Both Foxp3⁺CD25⁺ and Foxp3^–CD25^– CD4⁺ Regulatory T Cells

Jia-Bin Sun, Sukanya Raghavan, Åsa Sjöling, Samuel Lundin, and Jan Holmgren
J Immunol 2006 177: 7634-7644. [Abstract] [Full Text] [PDF]  

Regulation of Immunity by a Novel Population of Qa-1-Restricted CD8⁺TCR⁺ T Cells

Xiaolei Tang, Igor Maricic, Nikunj Purohit, Berge Bakamjian, Lisa M. Reed-Loisel, Tara Beeston, Peter Jensen, and Vipin Kumar
J Immunol 2006 177: 7645-7655. [Abstract] [Full Text] [PDF]  

Regulation of Th2 Cell Development by Polycomb Group Gene bmi-1 through the Stabilization of GATA3

Hiroyuki Hosokawa, Motoko Y. Kimura, Ryo Shinnakasu, Akane Suzuki, Takako Miki, Haruhiko Koseki, Maarten van Lohuizen, Masakatsu Yamashita, and Toshinori Nakayama
J Immunol 2006 177: 7656-7664. [Abstract] [Full Text] [PDF]  

Oncostatin M Enhances CCL21 Expression by Microvascular Endothelial Cells and Increases the Efficiency of Dendritic Cell Trafficking to Lymph Nodes

Makoto Sugaya, Lei Fang, Adela R. Cardones, Takashi Kakinuma, Samer H. Jaber, Andrew Blauvelt, and Sam T. Hwang
J Immunol 2006 177: 7665-7672. [Abstract] [Full Text] [PDF]  

Microenvironment-Dependent Requirement of STAT4 for the Induction of P-Selectin Ligands and Effector Cytokines on CD4⁺ T Cells in Healthy and Parasite-Infected Mice

Uta Syrbe, Ute Hoffmann, Kerstin Schlawe, Oliver Liesenfeld, Klaus Erb, and Alf Hamann
J Immunol 2006 177: 7673-7679. [Abstract] [Full Text] [PDF]  

Immunoproteasome Subunit Deficiencies Impact Differentially on Two Immunodominant Influenza Virus-Specific CD8⁺ T Cell Responses

Ken C. Pang, Megan T. Sanders, John J. Monaco, Peter C. Doherty, Stephen J. Turner, and Weisan Chen
J Immunol 2006 177: 7680-7688. [Abstract] [Full Text] [PDF]  

Cyclosporin A Abolishes CD28-Mediated Resistance to CD95-Induced Apoptosis via Superinduction of Caspase-3

Andreas Kerstan, Nicole Armbruster, Martin Leverkus, and Thomas Hünig
J Immunol 2006 177: 7689-7697. [Abstract] [Full Text] [PDF]  

Control of Memory CD4 T Cell Recall by the CD28/B7 Costimulatory Pathway

Modesta P. Ndejembi, John R. Teijaro, Deepa S. Patke, Adam W. Bingaman, Meena R. Chandok, Agnes Azimzadeh, Steven G. Nadler, and Donna L. Farber
J Immunol 2006 177: 7698-7706. [Abstract] [Full Text] [PDF]  

Talin1 Regulates TCR-Mediated LFA-1 Function

William T. N. Simonson, Santos J. Franco, and Anna Huttenlocher
J Immunol 2006 177: 7707-7714. [Abstract] [Full Text] [PDF]  

B Cell-Mediated Antigen Presentation Is Required for the Pathogenesis of Acute Cardiac Allograft Rejection

Hooman Noorchashm, Amy J. Reed, Susan Y. Rostami, Raha Mozaffari, Ghazal Zekavat, Brigitte Koeberlein, Andrew J. Caton, and Ali Naji
J Immunol 2006 177: 7715-7722. [Abstract] [Full Text] [PDF]  

Imprinting the Fate of Antigen-Reactive B Cells through the Affinity of the B Cell Receptor

Brian P. O’Connor, Laura A. Vogel, Weijun Zhang, William Loo, Danielle Shnider, Evan F. Lind, Michelle Ratliff, Randolph J. Noelle, and Loren D. Erickson
J Immunol 2006 177: 7723-7732. [Abstract] [Full Text] [PDF]  

Expression of Integrin ₃ Is Correlated to the Properties of Quiescent Hemopoietic Stem Cells Possessing the Side Population Phenotype

Terumasa Umemoto, Masayuki Yamato, Yoshiko Shiratsuchi, Masao Terasawa, Joseph Yang, Kohji Nishida, Yoshiro Kobayashi, and Teruo Okano
J Immunol 2006 177: 7733-7739. [Abstract] [Full Text] [PDF]  

TLR2/TLR4-Independent Neutrophil Activation and Recruitment upon Endocytosis of Nucleosomes Reveals a New Pathway of Innate Immunity in Systemic Lupus Erythematosus

Viktoria M. Rönnefarth, Annika I. M. Erbacher, Tobias Lamkemeyer, Johannes Madlung, Alfred Nordheim, Hans-Georg Rammensee, and Patrice Decker
J Immunol 2006 177: 7740-7749. [Abstract] [Full Text] [PDF]  

Dendritic Cells Amplify T Cell-Mediated Immune Responses in the Central Nervous System

Jozsef Karman, Hamlet H. Chu, Dominic O. Co, Christine M. Seroogy, Matyas Sandor, and Zsuzsanna Fabry
J Immunol 2006 177: 7750-7760. [Abstract] [Full Text] [PDF]  

IL-10 Inhibits Lipopolysaccharide-Induced CD40 Gene Expression through Induction of Suppressor of Cytokine Signaling-3

Hongwei Qin, Cynthia A. Wilson, Kevin L. Roberts, Brandi J. Baker, Xueyan Zhao, and Etty N. Benveniste
J Immunol 2006 177: 7761-7771. [Abstract] [Full Text] [PDF]  

Gut IgA Class Switch Recombination in the Absence of CD40 Does Not Occur in the Lamina Propria and Is Independent of Germinal Centers

Peter Bergqvist, Eva Gärdby, Anneli Stensson, Mats Bemark, and Nils Y. Lycke
J Immunol 2006 177: 7772-7783. [Abstract] [Full Text] [PDF]  

Characterization of Myeloid and Plasmacytoid Dendritic Cells in Human Lung

Barbara J. Masten, Gwyneth K. Olson, Christy A. Tarleton, Chad Rund, Mark Schuyler, Reza Mehran, Tereassa Archibeque, and Mary F. Lipscomb
J Immunol 2006 177: 7784-7793. [Abstract] [Full Text] [PDF]  

Regulation of Dendritic Cell Function and T Cell Priming by the Fatty Acid-Binding Protein aP2

Michael S. Rolph, Timothy R. Young, Bennett O. V. Shum, Cem Z. Gorgun, Carsten Schmitz-Peiffer, Ian A. Ramshaw, Gökhan S. Hotamisligil, and Charles R. Mackay
J Immunol 2006 177: 7794-7801. [Abstract] [Full Text] [PDF]  

Generation and Growth of CD28^nullCD8⁺ Memory T Cells Mediated by IL-15 and Its Induced Cytokines

Wai Kan Chiu, Monchou Fann, and Nan-ping Weng
J Immunol 2006 177: 7802-7810. [Abstract] [Full Text] [PDF]  

Cyclooxygenase-2 Inhibition Attenuates Antibody Responses against Human Papillomavirus-Like Particles

Elizabeth P. Ryan, Christine M. Malboeuf, Matthew Bernard, Robert C. Rose, and Richard P. Phipps
J Immunol 2006 177: 7811-7819. [Abstract] [Full Text] [PDF]  

A Regulatory CD4⁺ T Cell Subset in the BB Rat Model of Autoimmune Diabetes Expresses Neither CD25 Nor Foxp3

Jan-Luuk Hillebrands, Barbara Whalen, Jeroen T. J. Visser, Jasper Koning, Kenneth D. Bishop, Jean Leif, Jan Rozing, John P. Mordes, Dale L. Greiner, and Aldo A. Rossini
J Immunol 2006 177: 7820-7832. [Abstract] [Full Text] [PDF]  

Evidence for NK Cell Subsets Based on Chemokine Receptor Expression

Robert D. Berahovich, Nu L. Lai, Zheng Wei, Lewis L. Lanier, and Thomas J. Schall
J Immunol 2006 177: 7833-7840. [Abstract] [Full Text] [PDF]  

IFN--Mediated Up-Regulation of CD1d in Bacteria-Infected APCs

Gayatri Raghuraman, Yanbiao Geng, and Chyung-Ru Wang
J Immunol 2006 177: 7841-7848. [Abstract] [Full Text] [PDF]  

Heat Shock Protein 70 Is Secreted from Tumor Cells by a Nonclassical Pathway Involving Lysosomal Endosomes

Salamatu S. Mambula and Stuart K. Calderwood
J Immunol 2006 177: 7849-7857. [Abstract] [Full Text] [PDF]  

Spontaneous Large-Scale Lymphoid Neogenesis and Balanced Autoimmunity versus Tolerance in the Stomach of H⁺/K⁺-ATPase-Reactive TCR Transgenic Mouse

Tomoya Katakai, Takashi Nomura, Hiroyuki Gonda, Manabu Sugai, Yasutoshi Agata, Akiyoshi Nishio, Tohru Masuda, Shimon Sakaguchi, and Akira Shimizu
J Immunol 2006 177: 7858-7867. [Abstract] [Full Text] [PDF]  

Microarrays Reveal Distinct Gene Signatures in the Thymus of Seropositive and Seronegative Myasthenia Gravis Patients and the Role of CC Chemokine Ligand 21 in Thymic Hyperplasia

Rozen Le Panse, Géraldine Cizeron-Clairac, Jacky Bismuth, and Sonia Berrih-Aknin
J Immunol 2006 177: 7868-7879. [Abstract] [Full Text] [PDF] Data Supplement  

General Nature of the STAT3-Activated Anti-Inflammatory Response

Karim C. El Kasmi, Jeff Holst, Maryaline Coffre, Lisa Mielke, Antoine de Pauw, Nouara Lhocine, Amber M. Smith, Robert Rutschman, Deepak Kaushal, Yuhong Shen, Takashi Suda, Raymond P. Donnelly, Martin G. Myers, Jr., Warren Alexander, Dario A. A. Vignali, Stephanie S. Watowich, Matthias Ernst, Douglas J. Hilton, and Peter J. Murray
J Immunol 2006 177: 7880-7888. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Nucleocytoplasmic Shuttling of HMGB1 Is Regulated by Phosphorylation That Redirects It toward Secretion

Ju Ho Youn and Jeon-Soo Shin
J Immunol 2006 177: 7889-7897. [Abstract] [Full Text] [PDF]  

IFN Regulatory Factor 4 and 8 Promote Ig Light Chain Locus Activation in Pre-B Cell Development

Shibin Ma, Anna Turetsky, Long Trinh, and Runqing Lu
J Immunol 2006 177: 7898-7904. [Abstract] [Full Text] [PDF]  

Allergy-Driven Alternative Splicing of IL-13 Receptor 2 Yields Distinct Membrane and Soluble Forms

Yasuhiro Tabata, Weiguo Chen, Manoj R. Warrier, Aaron M. Gibson, Michael O. Daines, and Gurjit K. Khurana Hershey
J Immunol 2006 177: 7905-7912. [Abstract] [Full Text] [PDF]  

Analysis of the Individual Contributions of Ig (CD79a)- and Ig (CD79b)-Mediated Tonic Signaling for Bone Marrow B Cell Development and Peripheral B Cell Maturation

Ezequiel M. Fuentes-Pananá, Gregory Bannish, Fredrick G. Karnell, John F. Treml, and John G. Monroe
J Immunol 2006 177: 7913-7922. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Mapping of Quantitative Trait Loci Determining NK Cell-Mediated Resistance to MHC Class I-Deficient Bone Marrow Grafts in Perforin-Deficient Mice

Maria H. Johansson, Mesha A. Taylor, Maja Jagodic, Katalin Tus, John D. Schatzle, Edward K. Wakeland, and Michael Bennett
J Immunol 2006 177: 7923-7929. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Gene Expression Profiling Reveals Unique Pathways Associated with Differential Severity of Lyme Arthritis

Hillary Crandall, Diane M. Dunn, Ying Ma, R. Mark Wooten, James F. Zachary, John H. Weis, Robert B. Weiss, and Janis J. Weis
J Immunol 2006 177: 7930-7942. [Abstract] [Full Text] [PDF] Data Supplement  

Increased Natural CD4⁺CD25⁺ Regulatory T Cells and Their Suppressor Activity Do Not Contribute to Mortality in Murine Polymicrobial Sepsis

Philip O. Scumpia, Matthew J. Delano, Kindra M. Kelly, Kerri A. O’Malley, Philip A. Efron, Priscilla F. McAuliffe, Todd Brusko, Ricardo Ungaro, Tolga Barker, James L. Wynn, Mark A. Atkinson, Westley H. Reeves, Michael J. Clare Salzler, and Lyle L. Moldawer
J Immunol 2006 177: 7943-7949. [Abstract] [Full Text] [PDF]  

TLR4-Dependent NF-B Activation and Mitogen- and Stress-Activated Protein Kinase 1-Triggered Phosphorylation Events Are Central to Helicobacter pylori Peptidyl Prolyl cis-, trans-Isomerase (HP0175)-Mediated Induction of IL-6 Release from Macrophages

Sushil Kumar Pathak, Sanchita Basu, Asima Bhattacharyya, Shresh Pathak, Anirban Banerjee, Joyoti Basu, and Manikuntala Kundu
J Immunol 2006 177: 7950-7958. [Abstract] [Full Text] [PDF]  

Human Langerhans Cells Express a Specific TLR Profile and Differentially Respond to Viruses and Gram-Positive Bacteria

Vincent Flacher, Marielle Bouschbacher, Estelle Verronèse, Catherine Massacrier, Vanja Sisirak, Odile Berthier-Vergnes, Blandine de Saint-Vis, Christophe Caux, Colette Dezutter-Dambuyant, Serge Lebecque, and Jenny Valladeau
J Immunol 2006 177: 7959-7967. [Abstract] [Full Text] [PDF]  

The Role of TCR Engagement and Activation-Induced Cell Death in Sepsis-Induced T Cell Apoptosis

Jacqueline Unsinger, John M. Herndon, Christopher G. Davis, Jared T. Muenzer, Richard S. Hotchkiss, and Thomas A. Ferguson
J Immunol 2006 177: 7968-7973. [Abstract] [Full Text] [PDF]  

Antigen-Specific CD8⁺ T Cells Respond to Chlamydia trachomatis in the Genital Mucosa

Nadia R. Roan and Michael N. Starnbach
J Immunol 2006 177: 7974-7979. [Abstract] [Full Text] [PDF]  

TLR4 Mediates Vaccine-Induced Protective Cellular Immunity to Bordetella pertussis: Role of IL-17-Producing T Cells

Sarah C. Higgins, Andrew G. Jarnicki, Ed C. Lavelle, and Kingston H. G. Mills
J Immunol 2006 177: 7980-7989. [Abstract] [Full Text] [PDF]  

Interleukin-8 Induction by Helicobacter pylori in Gastric Epithelial Cells is Dependent on Apurinic/Apyrimidinic Endonuclease-1/Redox Factor-1

Ann M. O’Hara, Asima Bhattacharyya, Randy C. Mifflin, Michael F. Smith, Kieran A. Ryan, Kevin G.-E. Scott, Makoto Naganuma, Antonella Casola, Tadahide Izumi, Sankar Mitra, Peter B. Ernst, and Sheila E. Crowe
J Immunol 2006 177: 7990-7999. [Abstract] [Full Text] [PDF]  

Pseudomonas aeruginosa-Induced Human Mast Cell Apoptosis Is Associated with Up-Regulation of Endogenous Bcl-x_S and Down-Regulation of Bcl-x_L

Christopher E. Jenkins, Ania Swiatoniowski, Melanie R. Power, and Tong-Jun Lin
J Immunol 2006 177: 8000-8007. [Abstract] [Full Text] [PDF]  

The IFN-Independent Response to Virus Particle Entry Provides a First Line of Antiviral Defense That Is Independent of TLRs and Retinoic Acid-Inducible Gene I

Patrick Paladino, Derek T. Cummings, Ryan S. Noyce, and Karen L. Mossman
J Immunol 2006 177: 8008-8016. [Abstract] [Full Text] [PDF]  

A New Staphylococcal Anti-Inflammatory Protein That Antagonizes the Formyl Peptide Receptor-Like 1

Cristina Prat, Jovanka Bestebroer, Carla J. C. de Haas, Jos A. G. van Strijp, and Kok P. M. van Kessel
J Immunol 2006 177: 8017-8026. [Abstract] [Full Text] [PDF]  

Direct CD28 Costimulation Is Required for CD8⁺ T Cell-Mediated Resistance to an Acute Viral Disease in a Natural Host

Min Fang and Luis J. Sigal
J Immunol 2006 177: 8027-8036. [Abstract] [Full Text] [PDF]  

An HLA-A2.1-Transgenic Rabbit Model to Study Immunity to Papillomavirus Infection

Jiafen Hu, Xuwen Peng, Todd D. Schell, Lynn R. Budgeon, Nancy M. Cladel, and Neil D. Christensen
J Immunol 2006 177: 8037-8045. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

The Tumor-Promoting Effect of TNF- Involves the Induction of Secretory Leukocyte Protease Inhibitor

Nick Devoogdt, Hilde Revets, Anne Kindt, Yuan Qing Liu, Patrick De Baetselier, and Gholamreza Hassanzadeh Ghassabeh
J Immunol 2006 177: 8046-8052. [Abstract] [Full Text] [PDF]  

CXCL12 Limits Inflammation by Localizing Mononuclear Infiltrates to the Perivascular Space during Experimental Autoimmune Encephalomyelitis

Erin E. McCandless, Qiuling Wang, B. Mark Woerner, James M. Harper, and Robyn S. Klein
J Immunol 2006 177: 8053-8064. [Abstract] [Full Text] [PDF]  

Attenuating Burn Wound Inflammatory Signaling Reduces Systemic Inflammation and Acute Lung Injury

Kyros Ipaktchi, Aladdein Mattar, Andreas D. Niederbichler, Laszlo M. Hoesel, Sabrina Vollmannshauser, Mark R. Hemmila, Grace L. Su, Daniel G. Remick, Stewart C. Wang, and Saman Arbabi
J Immunol 2006 177: 8065-8071. [Abstract] [Full Text] [PDF]  

Macrophage Migration Inhibitory Factor Induces Macrophage Recruitment via CC Chemokine Ligand 2

Julia L. Gregory, Eric F. Morand, Sonja J. McKeown, Jennifer A. Ralph, Pamela Hall, Yuan H. Yang, Shaun R. McColl, and Michael J. Hickey
J Immunol 2006 177: 8072-8079. [Abstract] [Full Text] [PDF]  

The Differing Roles of the Classical and Mannose-Binding Lectin Complement Pathways in the Events following Skeletal Muscle Ischemia-Reperfusion

Rodney K. Chan, Shahrul I. Ibrahim, Kazue Takahashi, Edwin Kwon, Michael McCormack, Alan Ezekowitz, Michael C. Carroll, Francis D. Moore, Jr., and William G. Austen, Jr.
J Immunol 2006 177: 8080-8085. [Abstract] [Full Text] [PDF]  

The Duffy Antigen Modifies Systemic and Local Tissue Chemokine Responses following Lipopolysaccharide Stimulation

Janet S. Lee, Mark M. Wurfel, Gustavo Matute-Bello, Charles W. Frevert, Matthew R. Rosengart, Mrunalini Ranganathan, Venus W. Wong, Tarah Holden, Steve Sutlief, Ann Richmond, Stephen Peiper, and Thomas R. Martin
J Immunol 2006 177: 8086-8094. [Abstract] [Full Text] [PDF]  

Translational Regulation of Autoimmune Inflammation and Lymphoma Genesis by Programmed Cell Death 4

Anja Hilliard, Brendan Hilliard, Shi-Jun Zheng, Honghong Sun, Takashi Miwa, Wenchao Song, Rüdiger Göke, and Youhai H. Chen
J Immunol 2006 177: 8095-8102. [Abstract] [Full Text] [PDF]  

A Requirement for Microglial TLR4 in Leukocyte Recruitment into Brain in Response to Lipopolysaccharide

Hong Zhou, Benoît M. Lapointe, Stephen R. Clark, Lori Zbytnuik, and Paul Kubes
J Immunol 2006 177: 8103-8110. [Abstract] [Full Text] [PDF]  

Cyclooxygenase-2 Gene Transcription in a Macrophage Model of Inflammation

Yeon-Joo Kang, Byron A. Wingerd, Toshi Arakawa, and William L. Smith
J Immunol 2006 177: 8111-8122. [Abstract] [Full Text] [PDF]  

Neutrophils Are a Key Component of the Antitumor Efficacy of Topical Chemotherapy with Ingenol-3-Angelate

Jodie M. Challacombe, Andreas Suhrbier, Peter G. Parsons, Brad Jones, Peter Hampson, Dean Kavanagh, G. Ed Rainger, Melanie Morris, Janet M. Lord, Thuy T. T. Le, Diem Hoang-Le, and Steven M. Ogbourne
J Immunol 2006 177: 8123-8132. [Abstract] [Full Text] [PDF]  

Recombinant Soluble Forms of Extracellular TLR4 Domain and MD-2 Inhibit Lipopolysaccharide Binding on Cell Surface and Dampen Lipopolysaccharide-Induced Pulmonary Inflammation in Mice

Hiroaki Mitsuzawa, Chiaki Nishitani, Naoki Hyakushima, Takeyuki Shimizu, Hitomi Sano, Norio Matsushima, Koichi Fukase, and Yoshio Kuroki
J Immunol 2006 177: 8133-8139. [Abstract] [Full Text] [PDF]  

Gene Therapy of Arthritis with TCR Isolated from the Inflamed Paw

Keishi Fujio, Akiko Okamoto, Yasuto Araki, Hirofumi Shoda, Hiroyuki Tahara, Nelson H. Tsuno, Koki Takahashi, Toshio Kitamura, and Kazuhiko Yamamoto
J Immunol 2006 177: 8140-8147. [Abstract] [Full Text] [PDF]  

Annexin 1 Negatively Regulates IL-6 Expression via Effects on p38 MAPK and MAPK Phosphatase-1

Yuan H. Yang, Myew-Ling Toh, Colin D. Clyne, Michelle Leech, Daniel Aeberli, Jin Xue, April Dacumos, Laveena Sharma, and Eric F. Morand
J Immunol 2006 177: 8148-8153. [Abstract] [Full Text] [PDF]  

The Role of TLR2 In Vivo following Challenge with Staphylococcus aureus and Prototypic Ligands

Sarah C. Mullaly and Paul Kubes
J Immunol 2006 177: 8154-8163. [Abstract] [Full Text] [PDF]  

Oligodeoxynucleotides Differentially Modulate Activation of TLR7 and TLR8 by Imidazoquinolines

Keith K. B. Gorden, Xiaohong Qiu, John J. L. Battiste, Paul P. D. Wightman, John P. Vasilakos, and Sefik S. Alkan
J Immunol 2006 177: 8164-8170. [Abstract] [Full Text] [PDF]  

Plasminogen Activator Inhibitor Type-1-Deficient Mice Have an Enhanced IFN- Response to Lipopolysaccharide and Staphylococcal Enterotoxin B

Rosemarijn Renckens, Jennie M. Pater, and Tom van der Poll
J Immunol 2006 177: 8171-8176. [Abstract] [Full Text] [PDF]  

Selective Localization of Recognition Complexes for Leukotriene B4 and Formyl-Met-Leu-Phe within Lipid Raft Microdomains of Human Polymorphonuclear Neutrophils

Robert G. Sitrin, Sarah L. Emery, Timothy M. Sassanella, R. Alexander Blackwood, and Howard R. Petty
J Immunol 2006 177: 8177-8184. [Abstract] [Full Text] [PDF]  

Antigen-Specific Central Memory CD4⁺ T Lymphocytes Produce Multiple Cytokines and Proliferate In Vivo in Humans

Muriel Stubbe, Nathalie Vanderheyde, Michel Goldman, and Arnaud Marchant
J Immunol 2006 177: 8185-8190. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

CD8-Mediated Type 1 Antitumor Responses Selectively Modulate Endogenous Differentiated and Nondifferentiated T Cell Localization, Activation, and Function in Progressive Breast Cancer

Mark J. Dobrzanski, Joyce B. Reome, James C. Hylind, and Kathleen A. Rewers-Felkins
J Immunol 2006 177: 8191-8201. [Abstract] [Full Text] [PDF]  

IRAK-4 Mutation (Q293X): Rapid Detection and Characterization of Defective Post-Transcriptional TLR/IL-1R Responses in Human Myeloid and Non-Myeloid Cells

Donald J. Davidson, Andrew J. Currie, Dawn M. E. Bowdish, Kelly L. Brown, Carrie M. Rosenberger, Rebecca C. Ma, Johan Bylund, Paul A. Campsall, Anne Puel, Capucine Picard, Jean-Laurent Casanova, Stuart E. Turvey, Robert E. W. Hancock, Rebecca S. Devon, and David P. Speert
J Immunol 2006 177: 8202-8211. [Abstract] [Full Text] [PDF]  

Spontaneous CD8 T Cell Responses against the Melanocyte Differentiation Antigen RAB38/NY-MEL-1 in Melanoma Patients

Senta M. Walton, Marco Gerlinger, Olga de la Rosa, Natko Nuber, Ashley Knights, Asma Gati, Monika Laumer, Laura Strauss, Carolin Exner, Niklaus Schäfer, Mirjana Urosevic, Reinhard Dummer, Jean-Marie Tiercy, Andreas Mackensen, Elke Jaeger, Frédéric Lévy, Alexander Knuth, Dirk Jäger, and Alfred Zippelius
J Immunol 2006 177: 8212-8218. [Abstract] [Full Text] [PDF]  

Antibodies against the Activated Coagulation Factor X (FXa) in the Antiphospholipid Syndrome That Interfere with the FXa Inactivation by Antithrombin

Yao-Hsu Yang, Kwan-Ki Hwang, John FitzGerald, Jennifer M. Grossman, Mihaela Taylor, Bevra H. Hahn, and Pojen P. Chen
J Immunol 2006 177: 8219-8225. [Abstract] [Full Text] [PDF]  

Synovial Autoreactive T Cells in Rheumatoid Arthritis Resist IDO-Mediated Inhibition

Lingqiao Zhu, Fang Ji, Yuan Wang, Yi Zhang, Qiang Liu, Jingwu Z. Zhang, Kouji Matsushima, Qi Cao, and Yanyun Zhang
J Immunol 2006 177: 8226-8233. [Abstract] [Full Text] [PDF]  

Mimicry and Antibody-Mediated Cell Signaling in Autoimmune Myocarditis

Ya Li, Janet S. Heuser, Luke C. Cunningham, Stanley D. Kosanke, and Madeleine W. Cunningham
J Immunol 2006 177: 8234-8240. [Abstract] [Full Text] [PDF]  

Coadministration of Plasmid DNA Constructs Encoding an Encephalitogenic Determinant and IL-10 Elicits Regulatory T Cell-Mediated Protective Immunity in the Central Nervous System

Sagie Schif-Zuck, Gizi Wildbaum, and Nathan Karin
J Immunol 2006 177: 8241-8247. [Abstract] [Full Text] [PDF]  

Stability and Translation of TCR mRNA Are Regulated by the Adenosine-Uridine-Rich Elements in Splice-Deleted 3' Untranslated Region of -Chain

Bhabadeb Chowdhury, Sandeep Krishnan, Christos G. Tsokos, James W. Robertson, Carolyn U. Fisher, Madhusoodana P. Nambiar, and George C. Tsokos
J Immunol 2006 177: 8248-8257. [Abstract] [Full Text] [PDF]  

Role for Nephritogenic T Cells in Lupus Glomerulonephritis: Progression to Renal Failure Is Accompanied by T Cell Activation and Expansion in Regional Lymph Nodes

Harini Bagavant, Umesh S. Deshmukh, Hongyang Wang, Timothy Ly, and Shu Man Fu
J Immunol 2006 177: 8258-8265. [Abstract] [Full Text] [PDF]  

IL-22-Mediated Tumor Growth Reduction Correlates with Inhibition of ERK1/2 and AKT Phosphorylation and Induction of Cell Cycle Arrest in the G₂-M Phase

Georg F. Weber, Florian C. Gaertner, Wolfgang Erl, Klaus-Peter Janssen, Birgit Blechert, Bernhard Holzmann, Heike Weighardt, and Markus Essler
J Immunol 2006 177: 8266-8272. [Abstract] [Full Text] [PDF]  

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