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On the cover: Masson's trichrome staining of a lung section from a mouse deficient in the ectonucleotidase enzyme CD73, which regulates the production of extracellular adenosine. The mice were challenged with bleomycin to stimulate pulmonary fibrosis. Blue staining represents collagen deposition in the airways. Also evident are numerous inflammatory cells. Volmer, J. B., L. F. Thompson, and M. R. Blackburn. 2006. Ecto-5`-Nucleotidase (CD73)-Mediated Adenosine Production Is Tissue Protective in a Model of Bleomycin-Induced Lung Injury. J. Immunol. 176: 4449–4458.
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