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On the cover: Confocal immunofluorescence colocalization (yellow) of IgA Ab (green) and HIV envelope protein (red) in polarized, polymeric IgR-expressing epithelial cells transfected with HIV proviral DNA and then exposed to Ab at the basolateral surface. The image illustrates the initial step in intraepithelial cell neutralization of viral replication of IgA. Huang et al. Intraepithelial cell neutralization of HIV-1 replication of IgA. J. Immunol. 174:4828.
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