IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2005 174: 3135-3136. [Full Text] [PDF]  

BRIEF REVIEWS:

Leptin in Immunology

Giuseppe Matarese, Stergios Moschos, and Christos S. Mantzoros
J Immunol 2005 174: 3137-3142. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: The Prevalence of Regulatory T Cells in Lymphoid Tissue Is Correlated with Viral Load in HIV-Infected Patients

Jan Andersson, Adriano Boasso, Jakob Nilsson, Rui Zhang, Norah J. Shire, Stefan Lindback, Gene M. Shearer, and Claire A. Chougnet
J Immunol 2005 174: 3143-3147. [Abstract] [Full Text] [PDF]  

Cutting Edge: IL-10-Independent STAT3 Activation by Toxoplasma gondii Mediates Suppression of IL-12 and TNF- in Host Macrophages

Barbara A. Butcher, Leesun Kim, Athanasia D. Panopoulos, Stephanie S. Watowich, Peter J. Murray, and Eric Y. Denkers
J Immunol 2005 174: 3148-3152. [Abstract] [Full Text] [PDF]  

Cutting Edge: Signaling Lymphocytic Activation Molecule-Associated Protein Controls NKT Cell Functions

Brian Chung, Ala Aoukaty, Jan Dutz, Cox Terhorst, and Rusung Tan
J Immunol 2005 174: 3153-3157. [Abstract] [Full Text] [PDF]  

Cutting Edge: Recent Immune Status Determines the Source of Antigens That Drive Homeostatic T Cell Expansion

William C. Kieper, Amy Troy, J. Theodore Burghardt, Chris Ramsey, Joon Youb Lee, Han-Qing Jiang, Wolfgang Dummer, Hao Shen, John J. Cebra, and Charles D. Surh
J Immunol 2005 174: 3158-3163. [Abstract] [Full Text] [PDF]  

Cutting Edge: Stat5 Mediates the IL-7-Induced Accessibility of a Representative D-Distal V_H Gene

Michelle L. Stanton and Peter H. Brodeur
J Immunol 2005 174: 3164-3168. [Abstract] [Full Text] [PDF]  

Cutting Edge: Novel Role of Lipoxygenases in the Inflammatory Response: Promotion of TNF mRNA Decay by 15-Hydroperoxyeicosatetraenoic Acid in a Monocytic Cell Line

Judith V. Ferrante and Antonio Ferrante
J Immunol 2005 174: 3169-3172. [Abstract] [Full Text] [PDF]  

Cutting Edge: Spontaneously Ig-Secreting B-1 Cells Violate the Accepted Paradigm for Expression of Differentiation-Associated Transcription Factors

Joseph R. Tumang, Rubén Francés, Seung Geun Yeo, and Thomas L. Rothstein
J Immunol 2005 174: 3173-3177. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

The Mouse CD1d Cytoplasmic Tail Mediates CD1d Trafficking and Antigen Presentation by Adaptor Protein 3-Dependent and -Independent Mechanisms

Anna P. Lawton, Theodore I. Prigozy, Laurent Brossay, Bo Pei, Archana Khurana, Donald Martin, Tiancheng Zhu, Kira Späte, Megda Ozga, Stefan Höning, Oddmund Bakke, and Mitchell Kronenberg
J Immunol 2005 174: 3179-3186. [Abstract] [Full Text] [PDF]  

Rationally Engineered Therapeutic Proteins with Reduced Immunogenicity

Shabnam Tangri, Bianca R. Mothé, Julie Eisenbraun, John Sidney, Scott Southwood, Kristen Briggs, John Zinckgraf, Pamuk Bilsel, Mark Newman, Robert Chesnut, Cynthia LiCalsi, and Alessandro Sette
J Immunol 2005 174: 3187-3196. [Abstract] [Full Text] [PDF]  

CD4^– Plasmacytoid Dendritic Cells (pDCs) Migrate in Lymph Nodes by CpG Inoculation and Represent a Potent Functional Subset of pDCs

Guo-Xiang Yang, Zhe-Xiong Lian, Kentaro Kikuchi, Yong-Jun Liu, Aftab A. Ansari, Susumu Ikehara, and M. Eric Gershwin
J Immunol 2005 174: 3197-3203. [Abstract] [Full Text] [PDF]  

Clustering of T Cell Ligands on Artificial APC Membranes Influences T Cell Activation and Protein Kinase C Translocation to the T Cell Plasma Membrane

Francesca Giannoni, Joellen Barnett, Kun Bi, Rodrigo Samodal, Paola Lanza, Patrizia Marchese, Rosario Billetta, Randi Vita, Mark R. Klein, Berent Prakken, William W. Kwok, Eli Sercarz, Amnon Altman, and Salvatore Albani
J Immunol 2005 174: 3204-3211. [Abstract] [Full Text] [PDF]  

Impaired Cytolytic Activity in Calreticulin-Deficient CTLs

Simonetta Sipione, Catherine Ewen, Irene Shostak, Marek Michalak, and R. Chris Bleackley
J Immunol 2005 174: 3212-3219. [Abstract] [Full Text] [PDF]  

Mannose-Binding Lectin-Deficient Mice Display Defective Apoptotic Cell Clearance but No Autoimmune Phenotype

Lynda M. Stuart, Kazue Takahashi, Lei Shi, John Savill, and R. Alan B. Ezekowitz
J Immunol 2005 174: 3220-3226. [Abstract] [Full Text] [PDF]  

Heat Shock Protein 60 Inhibits Th1-Mediated Hepatitis Model via Innate Regulation of Th1/Th2 Transcription Factors and Cytokines

Alexandra Zanin-Zhorov, Rafael Bruck, Guy Tal, Shirly Oren, Hussein Aeed, Rami Hershkoviz, Irun R. Cohen, and Ofer Lider
J Immunol 2005 174: 3227-3236. [Abstract] [Full Text] [PDF]  

Probiotics Ameliorate Recurrent Th1-Mediated Murine Colitis by Inducing IL-10 and IL-10-Dependent TGF--Bearing Regulatory Cells

Claudia Di Giacinto, Mariarosaria Marinaro, Massimo Sanchez, Warren Strober, and Monica Boirivant
J Immunol 2005 174: 3237-3246. [Abstract] [Full Text] [PDF]  

Very Low-Dose Tolerance with Nucleosomal Peptides Controls Lupus and Induces Potent Regulatory T Cell Subsets

Hee-Kap Kang, Marissa A. Michaels, Beate R. Berner, and Syamal K. Datta
J Immunol 2005 174: 3247-3255. [Abstract] [Full Text] [PDF]  

Protein Conformation Significantly Influences Immune Responses to Prion Protein

Azadeh Khalili-Shirazi, Sonia Quaratino, Marco Londei, Linda Summers, Mourad Tayebi, Anthony R. Clarke, Simon H. Hawke, Graham S. Jackson, and John Collinge
J Immunol 2005 174: 3256-3263. [Abstract] [Full Text] [PDF]  

Coligation of the B Cell Receptor with Complement Receptor Type 2 (CR2/CD21) Using Its Natural Ligand C3dg: Activation without Engagement of an Inhibitory Signaling Pathway

Taras Lyubchenko, Joe Dal Porto, John C. Cambier, and V. Michael Holers
J Immunol 2005 174: 3264-3272. [Abstract] [Full Text] [PDF]  

Exacerbation of Granuloma Formation in IL-1 Receptor Antagonist-Deficient Mice with Impaired Dendritic Cell Maturation Associated with Th2 Cytokine Production

Hisashi Iizasa, Hiroyuki Yoneyama, Naofumi Mukaida, Yuki Katakoka, Makoto Naito, Nobuaki Yoshida, Emi Nakashima, and Kouji Matsushima
J Immunol 2005 174: 3273-3280. [Abstract] [Full Text] [PDF]  

-9-Tetrahydrocannabinol Enhances Breast Cancer Growth and Metastasis by Suppression of the Antitumor Immune Response

Robert J. McKallip, Mitzi Nagarkatti, and Prakash S. Nagarkatti
J Immunol 2005 174: 3281-3289. [Abstract] [Full Text] [PDF]  

The Generation of CD25⁺CD4⁺ Regulatory T Cells That Prevent Allograft Rejection Does Not Compromise Immunity to a Viral Pathogen

Andrew Bushell, Emma Jones, Awen Gallimore, and Kathryn Wood
J Immunol 2005 174: 3290-3297. [Abstract] [Full Text] [PDF]  

CD38 Controls ADP-Ribosyltransferase-2-Catalyzed ADP-Ribosylation of T Cell Surface Proteins

Christian Krebs, Sahil Adriouch, Fenja Braasch, Wolfgang Koestner, Edward H. Leiter, Michel Seman, Frances E. Lund, Norman Oppenheimer, Friedrich Haag, and Friedrich Koch-Nolte
J Immunol 2005 174: 3298-3305. [Abstract] [Full Text] [PDF]  

Identification of Stimulating and Inhibitory Epitopes within the Heat Shock Protein 70 Molecule That Modulate Cytokine Production and Maturation of Dendritic Cells

Yufei Wang, Trevor Whittall, Edward McGowan, Justine Younson, Charles Kelly, Lesley A. Bergmeier, Mahavir Singh, and Thomas Lehner
J Immunol 2005 174: 3306-3316. [Abstract] [Full Text] [PDF]  

The Immunogenicity of Dendritic Cell-Based Vaccines Is Not Hampered by Doxorubicin and Melphalan Administration

Anna Casati, Valérie S. Zimmermann, Fabio Benigni, Maria T. S. Bertilaccio, Matteo Bellone, and Anna Mondino
J Immunol 2005 174: 3317-3325. [Abstract] [Full Text] [PDF]  

Nucleosome, the Main Autoantigen in Systemic Lupus Erythematosus, Induces Direct Dendritic Cell Activation via a MyD88-Independent Pathway: Consequences on Inflammation

Patrice Decker, Harpreet Singh-Jasuja, Sabine Haager, Ina Kötter, and Hans-Georg Rammensee
J Immunol 2005 174: 3326-3334. [Abstract] [Full Text] [PDF]  

Mechanisms That Limit the In Vitro Proliferative Potential of Human CD8⁺ T Lymphocytes

Marco Migliaccio, Kenneth Raj, Olivier Menzel, and Nathalie Rufer
J Immunol 2005 174: 3335-3343. [Abstract] [Full Text] [PDF]  

Regulatory T Cells Suppress CD8⁺ T Cell Responses Induced by Direct Priming and Cross-Priming and Moderate Immunodominance Disparities

S. M. Mansour Haeryfar, Richard J. DiPaolo, David C. Tscharke, Jack R. Bennink, and Jonathan W. Yewdell
J Immunol 2005 174: 3344-3351. [Abstract] [Full Text] [PDF]  

Amelioration of Established Experimental Autoimmune Encephalomyelitis by an MHC Anchor-Substituted Variant of Proteolipid Protein 139–151

Carrie D. Margot, Mandy L. Ford, and Brian D. Evavold
J Immunol 2005 174: 3352-3358. [Abstract] [Full Text] [PDF]  

Opposing Roles for the Cyclin-Dependent Kinase Inhibitor p27^kip1 in the Control of CD4⁺ T Cell Proliferation and Effector Function

Emily A. Rowell, Matthew C. Walsh, and Andrew D. Wells
J Immunol 2005 174: 3359-3368. [Abstract] [Full Text] [PDF]  

B Cell Receptor (BCR) Cross-Talk: CD40 Engagement Enhances BCR-Induced ERK Activation

Takuya Mizuno and Thomas L. Rothstein
J Immunol 2005 174: 3369-3376. [Abstract] [Full Text] [PDF]  

B and T Lymphocyte Attenuator Exhibits Structural and Expression Polymorphisms and Is Highly Induced in Anergic CD4⁺ T Cells

Michelle A. Hurchla, John R. Sedy, Maya Gavrielli, Charles G. Drake, Theresa L. Murphy, and Kenneth M. Murphy
J Immunol 2005 174: 3377-3385. [Abstract] [Full Text] [PDF]  

T Cell Function Varies with the Expressed WC1 Coreceptor

Aric N. Rogers, Denille G. VanBuren, Emmett E. Hedblom, Mulualem E. Tilahun, Janice C. Telfer, and Cynthia L. Baldwin
J Immunol 2005 174: 3386-3393. [Abstract] [Full Text] [PDF]  

Small Rho GTPases Regulate Antigen Presentation in Dendritic Cells

Galina V. Shurin, Irina L. Tourkova, Gurkamal S. Chatta, Gudula Schmidt, Sheng Wei, Julie Y. Djeu, and Michael R. Shurin
J Immunol 2005 174: 3394-3400. [Abstract] [Full Text] [PDF]  

The Role of Intercellular Adhesion Molecule-1/LFA-1 Interactions in the Generation of Tumor-Specific CD8⁺ T Cell Responses

S. Rhiannon Jenkinson, Neil A. Williams, and David J. Morgan
J Immunol 2005 174: 3401-3407. [Abstract] [Full Text] [PDF]  

Role of the Programmed Death-1 Pathway in Regulation of Alloimmune Responses In Vivo

Sigrid E. Sandner, Michael R. Clarkson, Alan D. Salama, Alberto Sanchez-Fueyo, Christoph Domenig, Antje Habicht, Nader Najafian, Hideo Yagita, Miyuki Azuma, Laurence A. Turka, and Mohamed H. Sayegh
J Immunol 2005 174: 3408-3415. [Abstract] [Full Text] [PDF]  

ICAM-1 Contributes to but Is Not Essential for Tumor Antigen Cross-Priming and CD8⁺ T Cell-Mediated Tumor Rejection In Vivo

Christian Blank, Ian Brown, Aalok K. Kacha, Mary A. Markiewicz, and Thomas F. Gajewski
J Immunol 2005 174: 3416-3420. [Abstract] [Full Text] [PDF]  

Quantitating Effector and Regulatory T Lymphocytes in Immune Responses by Limiting Dilution Analysis Modeling

Thierry Bonnefoix, Philippe Bonnefoix, Pascal Perron, Jian-Qing Mi, Wan Fai Ng, Robert Lechler, Jean-Claude Bensa, Jean-Yves Cahn, and Dominique Leroux
J Immunol 2005 174: 3421-3431. [Abstract] [Full Text] [PDF]  

Cross-Priming of T Cell Responses by Synthetic Microspheres Carrying a CD8⁺ T Cell Epitope Requires an Adjuvant Signal

Florence Boisgérault, Paloma Rueda, Cheng Ming Sun, Sandra Hervas-Stubbs, Marie Rojas, and Claude Leclerc
J Immunol 2005 174: 3432-3439. [Abstract] [Full Text] [PDF]  

A Role for Caspases in Controlling IL-4 Expression in T Cells

Sarita Sehra, Dipak Patel, Saritha Kusam, Zheng-Yu Wang, Cheong-Hee Chang, and Alexander L. Dent
J Immunol 2005 174: 3440-3446. [Abstract] [Full Text] [PDF]  

Transplantation Tolerance in NF-B-Impaired Mice Is Not Due to Regulation but Is Prevented by Transgenic Expression of Bcl-x_L

Ping Zhou, Samuel J. Balin, Mona Mashayekhi, Kwang Woo Hwang, David A. Palucki, and Maria-Luisa Alegre
J Immunol 2005 174: 3447-3453. [Abstract] [Full Text] [PDF]  

VH1–46 Is the Dominant Immunoglobulin Heavy Chain Gene Segment in Rotavirus-Specific Memory B Cells Expressing the Intestinal Homing Receptor ₄₇

Jörn-Hendrik Weitkamp, Nicole L. Kallewaard, Amber L. Bowen, Bonnie J. LaFleur, Harry B. Greenberg, and James E. Crowe, Jr
J Immunol 2005 174: 3454-3460. [Abstract] [Full Text] [PDF]  

Cryptococcus neoformans Capsular Glucuronoxylomannan Induces Expression of Fas Ligand in Macrophages

Claudia Monari, Eva Pericolini, Giovanni Bistoni, Arturo Casadevall, Thomas R. Kozel, and Anna Vecchiarelli
J Immunol 2005 174: 3461-3468. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Solvent Accessibility of Native and Hydrolyzed Human Complement Protein 3 Analyzed by Hydrogen/Deuterium Exchange and Mass Spectrometry

Michael S. Winters, Daniel S. Spellman, and John D. Lambris
J Immunol 2005 174: 3469-3474. [Abstract] [Full Text] [PDF]  

Characterization of the Chicken C-Type Lectin-Like Receptors B-NK and B-lec Suggests That the NK Complex and the MHC Share a Common Ancestral Region

Sally L. Rogers, Thomas W. Göbel, Birgit C. Viertlboeck, Sarah Milne, Stephan Beck, and Jim Kaufman
J Immunol 2005 174: 3475-3483. [Abstract] [Full Text] [PDF]  

The Protooncogene c-Maf Is an Essential Transcription Factor for IL-10 Gene Expression in Macrophages

Shanjin Cao, Jianguo Liu, Lihua Song, and Xiaojing Ma
J Immunol 2005 174: 3484-3492. [Abstract] [Full Text] [PDF]  

Genes "Waiting" for Recruitment by the Adaptive Immune System: The Insights from Amphioxus

Cuiling Yu, Meiling Dong, Xiaokun Wu, Shengguo Li, Shengfeng Huang, Jing Su, Jianwen Wei, Yang Shen, Chunyan Mou, Xiaojin Xie, Jianghai Lin, Shaochun Yuan, Xuesong Yu, Yanhong Yu, Jingchun Du, Shicui Zhang, Xuanxian Peng, Mengqing Xiang, and Anlong Xu
J Immunol 2005 174: 3493-3500. [Abstract] [Full Text] [PDF] Data Supplement  

Molecular Basis for the High Affinity Interaction between the Thymic Leukemia Antigen and the CD8 Molecule

Antoine Attinger, Lesley Devine, Yiran Wang-Zhu, Donald Martin, Jia-huai Wang, Ellis L. Reinherz, Mitchell Kronenberg, Hilde Cheroutre, and Paula Kavathas
J Immunol 2005 174: 3501-3507. [Abstract] [Full Text] [PDF]  

Lipid Rafts Associate with Intracellular B Cell Receptors and Exhibit a B Cell Stage-Specific Protein Composition

Dirk Mielenz, Christian Vettermann, Martin Hampel, Christiane Lang, Athanasia Avramidou, Michael Karas, and Hans-Martin Jäck
J Immunol 2005 174: 3508-3517. [Abstract] [Full Text] [PDF]  

A Splice Variant of the TCR mRNA Lacking Exon 7 Leads to the Down-Regulation of TCR , the TCR/CD3 Complex, and IL-2 Production in Systemic Lupus Erythematosus T Cells

Kensei Tsuzaka, Yumiko Setoyama, Keiko Yoshimoto, Kiyono Shiraishi, Katsuya Suzuki, Tohru Abe, and Tsutomu Takeuchi
J Immunol 2005 174: 3518-3525. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Functional Domains of Runx1 Are Differentially Required for CD4 Repression, TCR Expression, and CD4/8 Double-Negative to CD4/8 Double-Positive Transition in Thymocyte Development

Masahito Kawazu, Takashi Asai, Motoshi Ichikawa, Go Yamamoto, Toshiki Saito, Susumu Goyama, Kinuko Mitani, Kohei Miyazono, Shigeru Chiba, Seishi Ogawa, Mineo Kurokawa, and Hisamaru Hirai
J Immunol 2005 174: 3526-3533. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

The IL-27 Receptor Chain WSX-1 Differentially Regulates Antibacterial Immunity and Survival during Experimental Tuberculosis

Christoph Hölscher, Alexandra Hölscher, Dominik Rückerl, Takayuki Yoshimoto, Hiroki Yoshida, Tak Mak, Christiaan Saris, and Stefan Ehlers
J Immunol 2005 174: 3534-3544. [Abstract] [Full Text] [PDF]  

Neisserial Porin-Induced Dendritic Cell Activation Is MyD88 and TLR2 Dependent

Theresa E. Singleton, Paola Massari, and Lee M. Wetzler
J Immunol 2005 174: 3545-3550. [Abstract] [Full Text] [PDF]  

Sphingosine Kinase 1 (SK1) Is Recruited to Nascent Phagosomes in Human Macrophages: Inhibition of SK1 Translocation by Mycobacterium tuberculosis

Christopher R. Thompson, Shankar S. Iyer, Natalie Melrose, Rebecca VanOosten, Korey Johnson, Stuart M. Pitson, Lina M. Obeid, and David J. Kusner
J Immunol 2005 174: 3551-3561. [Abstract] [Full Text] [PDF] Data Supplement  

Burkholderia cenocepacia Induces Neutrophil Necrosis in Chronic Granulomatous Disease

Johan Bylund, Paul A. Campsall, Rebecca C. Ma, Barbara-Ann D. Conway, and David P. Speert
J Immunol 2005 174: 3562-3569. [Abstract] [Full Text] [PDF]  

Influence of ESAT-6 Secretion System 1 (RD1) of Mycobacterium tuberculosis on the Interaction between Mycobacteria and the Host Immune System

Laleh Majlessi, Priscille Brodin, Roland Brosch, Marie-Jésus Rojas, Huot Khun, Michel Huerre, Stewart T. Cole, and Claude Leclerc
J Immunol 2005 174: 3570-3579. [Abstract] [Full Text] [PDF]  

Reovirus Serotype 1/Strain Lang-Stimulated Activation of Antigen-Specific T Lymphocytes in Peyer’s Patches and Distal Gut-Mucosal Sites: Activation Status and Cytotoxic Mechanisms

Mantej S. Bharhani, Jasvir S. Grewal, Mark J. Pilgrim, Candace Enocksen, Richard Peppler, Lucille London, and Steven D. London
J Immunol 2005 174: 3580-3589. [Abstract] [Full Text] [PDF]  

A Novel Role of IL-15 in Early Activation of Memory CD8⁺ CTL after Reinfection

Toshiki Yajima, Hitoshi Nishimura, Subash Sad, Hao Shen, Hiroyuki Kuwano, and Yasunobu Yoshikai
J Immunol 2005 174: 3590-3597. [Abstract] [Full Text] [PDF]  

Mechanisms of the Natural Reactivity of Lymphocytes from Noninfected Individuals to Membrane-Associated Leishmania infantum Antigens

Atfa Sassi, Beya Larguèche-Darwaz, Alexis Collette, Adrien Six, Dhafer Laouini, Pierre André Cazenave, and Koussay Dellagi
J Immunol 2005 174: 3598-3607. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Intracellular IL-1 Receptor Antagonist Type 1 Inhibits IL-1-Induced Cytokine Production in Keratinocytes through Binding to the Third Component of the COP9 Signalosome

Nirmal K. Banda, Carla Guthridge, Devon Sheppard, Kelly S. Cairns, Michele Muggli, Dawadschargal Bech-Otschir, Wolfgang Dubiel, and William P. Arend
J Immunol 2005 174: 3608-3616. [Abstract] [Full Text] [PDF]  

Involvement of BLT1 Endocytosis and Yes Kinase Activation in Leukotriene B₄-Induced Neutrophil Degranulation

Eric Gaudreault, Charles Thompson, Jana Stankova, and Marek Rola-Pleszczynski
J Immunol 2005 174: 3617-3625. [Abstract] [Full Text] [PDF]  

Stem Cell Factor Has a Suppressive Activity to IgE-Mediated Chemotaxis of Mast Cells

Junko Sawada, Shinya Shimizu, Takuya Tamatani, Shiro Kanegasaki, Hirohisa Saito, Akane Tanaka, Naotomo Kambe, Tatsutoshi Nakahata, and Hiroshi Matsuda
J Immunol 2005 174: 3626-3632. [Abstract] [Full Text] [PDF] Data Supplement  

Inhibition of Neutrophil Apoptosis by TLR Agonists in Whole Blood: Involvement of the Phosphoinositide 3-Kinase/Akt and NF-B Signaling Pathways, Leading to Increased Levels of Mcl-1, A1, and Phosphorylated Bad

Stéphanie François, Jamel El Benna, Pham M. C. Dang, Eric Pedruzzi, Marie-Anne Gougerot-Pocidalo, and Carole Elbim
J Immunol 2005 174: 3633-3642. [Abstract] [Full Text] [PDF]  

Pyocyanin Production by Pseudomonas aeruginosa Induces Neutrophil Apoptosis and Impairs Neutrophil-Mediated Host Defenses In Vivo

Lucy Allen, David H. Dockrell, Theresa Pattery, Daniel G. Lee, Pierre Cornelis, Paul G. Hellewell, and Moira K. B. Whyte
J Immunol 2005 174: 3643-3649. [Abstract] [Full Text] [PDF]  

The Nuclear IB Protein IBNS Selectively Inhibits Lipopolysaccharide-Induced IL-6 Production in Macrophages of the Colonic Lamina Propria

Tomonori Hirotani, Pui Y. Lee, Hirotaka Kuwata, Masahiro Yamamoto, Makoto Matsumoto, Ichiro Kawase, Shizuo Akira, and Kiyoshi Takeda
J Immunol 2005 174: 3650-3657. [Abstract] [Full Text] [PDF]  

Helicobacter pylori Disrupts NADPH Oxidase Targeting in Human Neutrophils to Induce Extracellular Superoxide Release

Lee-Ann H. Allen, Benjamin R. Beecher, Jeffrey T. Lynch, Olga V. Rohner, and Lara M. Wittine
J Immunol 2005 174: 3658-3667. [Abstract] [Full Text] [PDF]  

Manifestations of Inflammatory Arthritis Are Critically Dependent on LFA-1

Gerald M. Watts, Frank J. M. Beurskens, Ines Martin-Padura, Christie M. Ballantyne, Lloyd B. Klickstein, Michael B. Brenner, and David M. Lee
J Immunol 2005 174: 3668-3675. [Abstract] [Full Text] [PDF]  

Febrile-Range Hyperthermia Augments Neutrophil Accumulation and Enhances Lung Injury in Experimental Gram-Negative Bacterial Pneumonia

Penelope Rice, Erica Martin, Ju-Ren He, Mariah Frank, Louis DeTolla, Lisa Hester, Timothy O’Neill, Cheu Manka, Ivor Benjamin, Ashish Nagarsekar, Ishwar Singh, and Jeffrey D. Hasday
J Immunol 2005 174: 3676-3685. [Abstract] [Full Text] [PDF]  

The Human Herpes Virus 8-Encoded Chemokine Receptor Is Required for Angioproliferation in a Murine Model of Kaposi’s Sarcoma

Kristian K. Jensen, Denise J. Manfra, Marcos G. Grisotto, Andrea P. Martin, Galya Vassileva, Kevin Kelley, Thue W. Schwartz, and Sergio A. Lira
J Immunol 2005 174: 3686-3694. [Abstract] [Full Text] [PDF]  

IL-22 Inhibits Epidermal Differentiation and Induces Proinflammatory Gene Expression and Migration of Human Keratinocytes

Katia Boniface, François-Xavier Bernard, Martine Garcia, Austin L. Gurney, Jean-Claude Lecron, and Franck Morel
J Immunol 2005 174: 3695-3702. [Abstract] [Full Text] [PDF]  

Activation of the Prostaglandin D₂ Receptor DP2/CRTH2 Increases Allergic Inflammation in Mouse

Isabelle Spik, Céline Brénuchon, Véronique Angéli, Delphine Staumont, Sébastien Fleury, Monique Capron, François Trottein, and David Dombrowicz
J Immunol 2005 174: 3703-3708. [Abstract] [Full Text] [PDF]  

Unconjugated Bilirubin Inhibits VCAM-1-Mediated Transendothelial Leukocyte Migration

Pavitra Keshavan, Tracy L. Deem, Sandy J. Schwemberger, George F. Babcock, Joan M. Cook-Mills, and Stephen D. Zucker
J Immunol 2005 174: 3709-3718. [Abstract] [Full Text] [PDF]  

The Cytokine IL-1 Activates IFN Response Factor 3 in Human Fetal Astrocytes in Culture

Mark A. Rivieccio, Gareth R. John, Xianyuan Song, Hyeon-Sook Suh, Yongmei Zhao, Sunhee C. Lee, and Celia F. Brosnan
J Immunol 2005 174: 3719-3726. [Abstract] [Full Text] [PDF]  

Modulation of Phagocytosis of Apoptotic Neutrophils by Supernatant from Dexamethasone-Treated Macrophages and Annexin-Derived Peptide Ac_2–26

Paola Maderna, Simon Yona, Mauro Perretti, and Catherine Godson
J Immunol 2005 174: 3727-3733. [Abstract] [Full Text] [PDF]  

Indispensable Role of Stat5a in Stat6-Independent Th2 Cell Differentiation and Allergic Airway Inflammation

Hiroaki Takatori, Hiroshi Nakajima, Koichi Hirose, Shin-ichiro Kagami, Tomohiro Tamachi, Akira Suto, Kotaro Suzuki, Yasushi Saito, and Itsuo Iwamoto
J Immunol 2005 174: 3734-3740. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Alloreactive T Cell Responses and Acute Rejection of Single Class II MHC-Disparate Heart Allografts Are under Strict Regulation by CD4⁺CD25⁺ T Cells

Soren Schenk, Danielle D. Kish, Chunshui He, Tarek El-Sawy, Eise Chiffoleau, Chuangqui Chen, Zihao Wu, Sigrid Sandner, Anton V. Gorbachev, Kiyotaka Fukamachi, Peter S. Heeger, Mohamed H. Sayegh, Laurence A. Turka, and Robert L. Fairchild
J Immunol 2005 174: 3741-3748. [Abstract] [Full Text] [PDF]  

B Cell Response to Surface IgM Cross-Linking Identifies Different Prognostic Groups of B-Chronic Lymphocytic Leukemia Patients

Steven Nédellec, Yves Renaudineau, Anne Bordron, Christian Berthou, Nina Porakishvili, Peter M. Lydyard, Jacques-Olivier Pers, and Pierre Youinou
J Immunol 2005 174: 3749-3756. [Abstract] [Full Text] [PDF]  

Differential Regulation of Granzyme and Perforin in Effector and Memory T Cells following Smallpox Immunization

Michael T. Rock, Sandra M. Yoder, Peter F. Wright, Thomas R. Talbot, Kathryn M. Edwards, and James E. Crowe, Jr
J Immunol 2005 174: 3757-3764. [Abstract] [Full Text] [PDF]  

Prolonged Lymphopenia, Lymphoid Depletion, and Hypoprolactinemia in Children with Nosocomial Sepsis and Multiple Organ Failure

Kate A. Felmet, Mark W. Hall, Robert S. B. Clark, Ronald Jaffe, and Joseph A. Carcillo
J Immunol 2005 174: 3765-3772. [Abstract] [Full Text] [PDF]  

CD1a and CD1c Activate Intrathyroidal T Cells during Graves’ Disease and Hashimoto’s Thyroiditis

Carme Roura-Mir, Marta Catálfamo, Tan-Yun Cheng, Ellen Marqusee, Gurdyal S. Besra, Dolores Jaraquemada, and D. Branch Moody
J Immunol 2005 174: 3773-3780. [Abstract] [Full Text] [PDF]  

Antigen-Specific B Cells Are Required as APCs and Autoantibody-Producing Cells for Induction of Severe Autoimmune Arthritis

Shannon K. O’Neill, Mark J. Shlomchik, Tibor T. Glant, Yanxia Cao, Paul D. Doodes, and Alison Finnegan
J Immunol 2005 174: 3781-3788. [Abstract] [Full Text] [PDF]  

IL-10-Dependent Suppression of Experimental Allergic Encephalomyelitis by Th2-Differentiated, Anti-TCR Redirected T Lymphocytes

Divya J. Mekala, Rajshekhar S. Alli, and Terrence L. Geiger
J Immunol 2005 174: 3789-3797. [Abstract] [Full Text] [PDF]  

Telomerase mRNA-Transfected Dendritic Cells Stimulate Antigen-Specific CD8⁺ and CD4⁺ T Cell Responses in Patients with Metastatic Prostate Cancer

Zhen Su, Jens Dannull, Benjamin K. Yang, Philipp Dahm, Doris Coleman, Donna Yancey, Sylvia Sichi, Donna Niedzwiecki, David Boczkowski, Eli Gilboa, and Johannes Vieweg
J Immunol 2005 174: 3798-3807. [Abstract] [Full Text] [PDF]  

Immunization with Lentiviral Vector-Transduced Dendritic Cells Induces Strong and Long-Lasting T Cell Responses and Therapeutic Immunity

Yukai He, Jiying Zhang, Zhibao Mi, Paul Robbins, and Louis D. Falo, Jr
J Immunol 2005 174: 3808-3817. [Abstract] [Full Text] [PDF]  

CORRECTIONS:

Mature Human Langerhans Cells Derived from CD34⁺ Hematopoietic Progenitors Stimulate Greater Cytolytic T Lymphocyte Activity in the Absence of Bioactive IL-12p70, by Either Single Peptide Presentation or Cross-Priming, Than Do Dermal-Interstitial or Monocyte-Derived Dendritic Cells.

Gundrun Ratzinger, Jan Baggers, Maria A. de Cos, Jianda Yuan, Tao Dao, John L. Reagan, Christian Münz, Glenn Heller, and James W. Young
J Immunol 2005 174: 3818. [Full Text] [PDF]  

Crucial Role of Inhibitor of DNA Binding/Differentiation in the Vascular Endothelial Growth Factor-Induced Activation and Angiogenic Processes of Human Endothelial Cells.

Daisuke Sakurai, Naoyuki Tsuchiya, Akihiro Yamaguchi, Yurai Okaji, Nelson H. Tsuno, Tetsuji Kobata, Koki Takahashi, and Katsushi Tokunaga
J Immunol 2005 174: 3818. [Full Text] [PDF]  

Fas Death Receptor Signaling Represses Monocyte Numbers and Macrophage Activation In Vivo.

Nathaniel J. Brown, Jack Hutcheson, Emily Bickel, John C. Scatizzi, Lee D. Albee, G. Kenneth Haines, III, Joy Eslick, Kathleen Bradley, Elsa Taricone, and Harris Perlman
J Immunol 2005 174: 3818. [Full Text] [PDF]  

Enhanced Tolerance to Autoimmune Uveitis in CD200-Deficient Mice Correlates with a Pronounced Th2 Switch in Response to Antigen Challenge.

Neil Taylor, Karen McConnachie, Claudia Calder, Rosemary Dawson, Andrew Dick, Jonathon D. Sedgwick, and Janet Liversidge
J Immunol 2005 174: 3818. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.