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IN THIS ISSUE: J Immunol 2005 174: 5905-5906. [Full Text] [PDF]

BRIEF REVIEWS:

License to Heal: Bidirectional Interaction of Antigen-Specific Regulatory T Cells and Tolerogenic APC: George Vlad, Raffaello Cortesini, and Nicole Suciu-Foca
J Immunol 2005 174: 5907-5914. [Abstract] [Full Text] [PDF]

CUTTING EDGE:

Cutting Edge: CD95 Maintains Effector T Cell Homeostasis in Chronic Immune Activation: Ramon Arens, Paul A. Baars, Margot Jak, Kiki Tesselaar, Martin van der Valk, Marinus H. J. van Oers, and René A. W. van Lier
J Immunol 2005 174: 5915-5920. [Abstract] [Full Text] [PDF]

Cutting Edge: The Acquisition of TLR Tolerance during Malaria Infection Impacts T Cell Activation: James A. Perry, Christine S. Olver, Robert C. Burnett, and Anne C. Avery
J Immunol 2005 174: 5921-5925. [Abstract] [Full Text] [PDF]

Cutting Edge: Emergence of CD127^high Functionally Competent Memory T Cells Is Compromised by High Viral Loads and Inadequate T Cell Help: Michael J. Fuller, David A. Hildeman, Steffanie Sabbaj, Dalia E. Gaddis, Anne E. Tebo, Liang Shang, Paul A. Goepfert, and Allan J. Zajac
J Immunol 2005 174: 5926-5930. [Abstract] [Full Text] [PDF]

Cutting Edge: The SLAM Family Receptor Ly108 Controls T Cell and Neutrophil Functions: Duncan Howie, F. Stephen Laroux, Massimo Morra, Abhay R. Satoskar, Lucia E. Rosas, William A. Faubion, Aimee Julien, Svend Rietdijk, Anthony J. Coyle, Christopher Fraser, and Cox Terhorst
J Immunol 2005 174: 5931-5935. [Abstract] [Full Text] [PDF]

Cutting Edge: Re-evaluating the In Vivo Cytokine Responses of CD8⁺ T Cells during Primary and Secondary Viral Infections: Fei Liu and J. Lindsay Whitton
J Immunol 2005 174: 5936-5940. [Abstract] [Full Text] [PDF]

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Effects of Cytokines on Acetylcholine Receptor Expression: Implications for Myasthenia Gravis: Sandrine Poëa-Guyon, Premkumar Christadoss, Rozen Le Panse, Thierry Guyon, Marc De Baets, Abdelilah Wakkach, Jocelyne Bidault, Socrates Tzartos, and Sonia Berrih-Aknin
J Immunol 2005 174: 5941-5949. [Abstract] [Full Text] [PDF]

TGF- ${beta}$ 1 Uses Distinct Mechanisms to Inhibit IFN- ${gamma}$ Expression in CD4⁺ T Cells at Priming and at Recall: Differential Involvement of Stat4 and T-bet: Jack T. Lin, Stacey L. Martin, Luxi Xia, and James D. Gorham
J Immunol 2005 174: 5950-5958. [Abstract] [Full Text] [PDF]

CD4⁺CD25⁺ Regulatory T Cells Attenuate the Phosphatidylinositol 3-Kinase/Akt Pathway in Antigen-Primed Immature CD8⁺ CTLs during Functional Maturation: Hidefumi Kojima, Yumiko Kanno, Hidenori Hase, and Tetsuji Kobata
J Immunol 2005 174: 5959-5967. [Abstract] [Full Text] [PDF]

Intravenous Infusion of Syngeneic Apoptotic Cells by Photopheresis Induces Antigen-Specific Regulatory T Cells: Akira Maeda, Agatha Schwarz, Kerstin Kernebeck, Nicole Gross, Yoshinori Aragane, David Peritt, and Thomas Schwarz
J Immunol 2005 174: 5968-5976. [Abstract] [Full Text] [PDF]

Identification of Grb2 As a Novel Binding Partner of the Signaling Lymphocytic Activation Molecule-Associated Protein Binding Receptor CD229: Margarita Martín, Juana M. Del Valle, Ifigènia Saborit, and Pablo Engel
J Immunol 2005 174: 5977-5986. [Abstract] [Full Text] [PDF]

TGF- ${beta}$ 1 Inhibits Mast Cell Fc ${epsilon}$ RI Expression: Gregorio Gomez, Carlos D. Ramirez, Juan Rivera, Manish Patel, Farnaz Norozian, Harry V. Wright, Mohit V. Kashyap, Brian O. Barnstein, Krista Fischer-Stenger, Lawrence B. Schwartz, Christopher L. Kepley, and John J. Ryan
J Immunol 2005 174: 5987-5993. [Abstract] [Full Text] [PDF]

Multiple Costimulatory Modalities Enhance CTL Avidity: James W. Hodge, Mala Chakraborty, Chie Kudo-Saito, Charlie T. Garnett, and Jeffrey Schlom
J Immunol 2005 174: 5994-6004. [Abstract] [Full Text] [PDF]

IFN Regulatory Factor-2 Deficiency Revealed a Novel Checkpoint Critical for the Generation of Peripheral NK Cells: Shinsuke Taki, Shinsuke Nakajima, Eri Ichikawa, Takashi Saito, and Shigeaki Hida
J Immunol 2005 174: 6005-6012. [Abstract] [Full Text] [PDF]

CD40 Ligation Activates Murine Macrophages via an IFN- ${gamma}$ -Dependent Mechanism Resulting in Tumor Cell Destruction In Vitro: Ilia N. Buhtoiarov, Hillary Lum, Gideon Berke, Donna M. Paulnock, Paul M. Sondel, and Alexander L. Rakhmilevich
J Immunol 2005 174: 6013-6022. [Abstract] [Full Text] [PDF]

Estrogen Regulates CCR Gene Expression and Function in T Lymphocytes: RuRan Mo, Jun Chen, Annabelle Grolleau-Julius, Hedwig S. Murphy, Bruce C. Richardson, and Raymond L. Yung
J Immunol 2005 174: 6023-6029. [Abstract] [Full Text] [PDF]

Cyclophilin A-Deficient Mice Are Resistant to Immunosuppression by Cyclosporine: John Colgan, Mohammed Asmal, Bin Yu, and Jeremy Luban
J Immunol 2005 174: 6030-6038. [Abstract] [Full Text] [PDF]

Spontaneous and Homeostatic Proliferation of CD4 T Cells Are Regulated by Different Mechanisms: Booki Min, Hidehiro Yamane, Jane Hu-Li, and William E. Paul
J Immunol 2005 174: 6039-6044. [Abstract] [Full Text] [PDF]

${gamma}$ ${delta}$ T Cells Respond Directly to Pathogen-Associated Molecular Patterns: Jodi F. Hedges, Kirk J. Lubick, and Mark A. Jutila
J Immunol 2005 174: 6045-6053. [Abstract] [Full Text] [PDF]

Pertussis Toxin (PTX) B Subunit and the Nontoxic PTX Mutant PT9K/129G Inhibit Tat-Induced TGF- ${beta}$ Production by NK Cells and TGF- ${beta}$ -Mediated NK Cell Apoptosis: M. Raffaella Zocchi, Paola Contini, Massimo Alfano, and Alessandro Poggi
J Immunol 2005 174: 6054-6061. [Abstract] [Full Text] [PDF]

B Cell Receptor (BCR) Cross-Talk: CD40 Engagement Creates an Alternate Pathway for BCR Signaling That Activates I ${kappa}$ B Kinase/I ${kappa}$ B ${alpha}$ /NF- ${kappa}$ B without the Need for PI3K and Phospholipase C ${gamma}$: Takuya Mizuno and Thomas L. Rothstein
J Immunol 2005 174: 6062-6070. [Abstract] [Full Text] [PDF]

Selective Expression of the 21-Kilodalton Tyrosine-Phosphorylated Form of TCR ${zeta}$ Promotes the Emergence of T Cells with Autoreactive Potential: Lisa A. Pitcher, Meredith A. Mathis, Srividya Subramanian, Jennifer A. Young, Edward K. Wakeland, Paul E. Love, and Nicolai S. C. van Oers
J Immunol 2005 174: 6071-6079. [Abstract] [Full Text] [PDF]

Preferential Cell Death of CD8⁺ Effector Memory (CCR7^–CD45RA^–) T Cells by Hydrogen Peroxide-Induced Oxidative Stress: Akihiro Takahashi, Mikael G. V. Hanson, Håkan R. Norell, Aleksandra Mandic Havelka, Koji Kono, Karl-Johan Malmberg, and Rolf V. R. Kiessling
J Immunol 2005 174: 6080-6087. [Abstract] [Full Text] [PDF]

Expression of Killer Cell Lectin-Like Receptor G1 on Antigen-Specific Human CD8⁺ T Lymphocytes during Active, Latent, and Resolved Infection and its Relation with CD57: Chris C. Ibegbu, Yong-Xian Xu, Wayne Harris, David Maggio, Joseph D. Miller, and Athena P. Kourtis
J Immunol 2005 174: 6088-6094. [Abstract] [Full Text] [PDF]

Reactive Oxygen Species and 12/15-Lipoxygenase Contribute to the Antiproliferative Capacity of Alternatively Activated Myeloid Cells Elicited during Helminth Infection: Lea Brys, Alain Beschin, Geert Raes, Gholamreza Hassanzadeh Ghassabeh, Wim Noël, Jef Brandt, Frank Brombacher, and Patrick De Baetselier
J Immunol 2005 174: 6095-6104. [Abstract] [Full Text] [PDF]

Tid1 Is Required for T Cell Transition from Double-Negative 3 to Double-Positive Stages: Jeng-Fan Lo, He Zhou, Colleen Fearns, Ralph A. Reisfeld, Young Yang, and Jiing-Dwan Lee
J Immunol 2005 174: 6105-6112. [Abstract] [Full Text] [PDF]

CpG-Independent Synergistic Induction of ${beta}$ -Chemokines and a Dendritic Cell Phenotype by Orthophosphorothioate Oligodeoxynucleotides and Granulocyte-Macrophage Colony-Stimulating Factor in Elutriated Human Primary Monocytes: Jinhai Wang, Raymond Alvarez, Gregory Roderiquez, Ennan Guan, Quincy Caldwell, Jiun Wang, Michael Phelan, and Michael A. Norcross
J Immunol 2005 174: 6113-6121. [Abstract] [Full Text] [PDF]

Impaired TGF- ${beta}$ Responses in Peripheral T Cells of G ${alpha}$ i2^–/– Mice: Jim Y. Wu, YongZhu Jin, Robert A. Edwards, Yujin Zhang, Milton J. Finegold, and Mei X. Wu
J Immunol 2005 174: 6122-6128. [Abstract] [Full Text] [PDF]

Endosomal Translocation of Vertebrate DNA Activates Dendritic Cells via TLR9-Dependent and -Independent Pathways: Kei Yasuda, Philipp Yu, Carsten J. Kirschning, Beatrix Schlatter, Frank Schmitz, Antje Heit, Stefan Bauer, Hubertus Hochrein, and Hermann Wagner
J Immunol 2005 174: 6129-6136. [Abstract] [Full Text] [PDF]

TGF- ${alpha}$ Regulates TLR Expression and Function on Epidermal Keratinocytes: Lloyd S. Miller, Ole E. Sørensen, Philip T. Liu, H. Ray Jalian, Deborah Eshtiaghpour, Behnaz E. Behmanesh, Woosin Chung, Timothy D. Starner, Jenny Kim, Peter A. Sieling, Tomas Ganz, and Robert L. Modlin
J Immunol 2005 174: 6137-6143. [Abstract] [Full Text] [PDF]

Transcriptional Profiling of ${gamma}$ ${delta}$ T Cells Identifies a Role for Vitamin D in the Immunoregulation of the V ${gamma}$ 9V ${delta}$ 2 Response to Phosphate-Containing Ligands: Lanfen Chen, Maria Teresa Cencioni, Daniela F. Angelini, Giovanna Borsellino, Luca Battistini, and Celia F. Brosnan
J Immunol 2005 174: 6144-6152. [Abstract] [Full Text] [PDF]

An Ancient Role for a Prokineticin Domain in Invertebrate Hematopoiesis: Irene Söderhäll, Young-A Kim, Pikul Jiravanichpaisal, So-Young Lee, and Kenneth Söderhäll
J Immunol 2005 174: 6153-6160. [Abstract] [Full Text] [PDF]

Testicular Immune Privilege Promotes Transplantation Tolerance by Altering the Balance between Memory and Regulatory T Cells: Isam W. Nasr, Yinong Wang, Ge Gao, Songyan Deng, Lonnette Diggs, David M. Rothstein, George Tellides, Fadi G. Lakkis, and Zhenhua Dai
J Immunol 2005 174: 6161-6168. [Abstract] [Full Text] [PDF]

TGF- ${beta}$ Inhibits Fas-Mediated Apoptosis of a Follicular Dendritic Cell Line by Down-Regulating the Expression of Fas and Caspase-8: Counteracting Role of TGF- ${beta}$ on TNF Sensitization of Fas-Mediated Apoptosis: Sun-Mi Park, Sunshin Kim, Jin-Suk Choi, Dae-Young Hur, Wang-Jae Lee, Myung-Shik Lee, Jongseon Choe, and Tae H. Lee
J Immunol 2005 174: 6169-6175. [Abstract] [Full Text] [PDF]

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Interallelic Class Switch Recombination Contributes Significantly to Class Switching in Mouse B Cells: Stéphane Reynaud, Laurent Delpy, Laurence Fleury, Hei-Lanne Dougier, Christophe Sirac, and Michel Cogné
J Immunol 2005 174: 6176-6183. [Abstract] [Full Text] [PDF]

Enforced Expression of Spi-B Reverses T Lineage Commitment and Blocks ${beta}$ -Selection: Juliette M. Lefebvre, Mariëlle C. Haks, Michael O. Carleton, Michele Rhodes, Gomathinayagam Sinnathamby, M. Celeste Simon, Laurence C. Eisenlohr, Lee Ann Garrett-Sinha, and David L. Wiest
J Immunol 2005 174: 6184-6194. [Abstract] [Full Text] [PDF]

Mechanisms of Dimethyl Sulfoxide Augmentation of IL-1 ${beta}$ Production: Liyu Xing and Daniel G. Remick
J Immunol 2005 174: 6195-6202. [Abstract] [Full Text] [PDF]

IFN- ${gamma}$ -Stimulated Transcriptional Activation by IFN- ${gamma}$ -Activated Transcriptional Element-Binding Factor 1 Occurs via an Inducible Interaction with CAAAT/Enhancer-Binding Protein- ${beta}$: Qingjun Meng, Abhijit Raha, Sanjit Roy, Junbo Hu, and Dhananjaya V. Kalvakolanu
J Immunol 2005 174: 6203-6211. [Abstract] [Full Text] [PDF]

Demethylation of the Same Promoter Sequence Increases CD70 Expression in Lupus T Cells and T Cells Treated with Lupus-Inducing Drugs: Qianjin Lu, Ailing Wu, and Bruce C. Richardson
J Immunol 2005 174: 6212-6219. [Abstract] [Full Text] [PDF]

Beyond the 12/23 Rule of VDJ Recombination Independent of the Rag Proteins: Alexandru Olaru, Howard T. Petrie, and Ferenc Livák
J Immunol 2005 174: 6220-6226. [Abstract] [Full Text] [PDF]

Recombinant C345C and Factor I Modules of Complement Components C5 and C7 Inhibit C7 Incorporation into the Complement Membrane Attack Complex: Chuong-Thu Thai and Ronald T. Ogata
J Immunol 2005 174: 6227-6232. [Abstract] [Full Text] [PDF]

A New Tyrosine Phosphorylation Site in PLC ${gamma}$ 1: The Role of Tyrosine 775 in Immune Receptor Signaling: Carmen J. Serrano, Laurie Graham, Karen DeBell, Rashmi Rawat, Maria Concetta Veri, Ezio Bonvini, Barbara L. Rellahan, and Ilona G. Reischl
J Immunol 2005 174: 6233-6237. [Abstract] [Full Text] [PDF]

Transcriptional Regulation of the Human CD3 ${gamma}$ Gene: The TATA-Less CD3 ${gamma}$ Promoter Functions via an Initiator and Contiguous Sp-Binding Elements: Bassam M. Badran, Kevin Kunstman, Jennifer Stanton, Maria Moschitta, Anne Zerghe, Haidar Akl, Arsène Burny, Steven M. Wolinsky, and Karen E. Willard-Gallo
J Immunol 2005 174: 6238-6249. [Abstract] [Full Text] [PDF]

Human Factor H-Related Protein 5 Has Cofactor Activity, Inhibits C3 Convertase Activity, Binds Heparin and C-Reactive Protein, and Associates with Lipoprotein: Jennifer L. McRae, Thomas G. Duthy, Kim M. Griggs, Rebecca J. Ormsby, Peter J. Cowan, Brett A. Cromer, William J. McKinstry, Michael W. Parker, Brendan F. Murphy, and David L. Gordon
J Immunol 2005 174: 6250-6256. [Abstract] [Full Text] [PDF]

HOST DEFENSE:

Mouse Cathelin-Related Antimicrobial Peptide Chemoattracts Leukocytes Using Formyl Peptide Receptor-Like 1/Mouse Formyl Peptide Receptor-Like 2 as the Receptor and Acts as an Immune Adjuvant: Kahori Kurosaka, Qian Chen, Felix Yarovinsky, Joost J. Oppenheim, and De Yang
J Immunol 2005 174: 6257-6265. [Abstract] [Full Text] [PDF]

Protective Immunity to Genital Herpes Simpex Virus Type 2 Infection Is Mediated by T-bet: Alexandra Svensson, Inger Nordström, Jia-Bin Sun, and Kristina Eriksson
J Immunol 2005 174: 6266-6273. [Abstract] [Full Text] [PDF]

Analysis of the 5q31-q33 Locus Shows an Association between IL13-1055C/T IL-13-591A/G Polymorphisms and Schistosoma haematobium Infections: Bourema Kouriba, Christophe Chevillard, Jay H. Bream, Laurent Argiro, Helia Dessein, Violaine Arnaud, Lansana Sangare, Abdoulaye Dabo, Abdou Habib Beavogui, Charles Arama, Hamar A. Traoré, Ogobara Doumbo, and Alain Dessein
J Immunol 2005 174: 6274-6281. [Abstract] [Full Text] [PDF]

Dendritic Cells Cross-Present Exogenous Fungal Antigens to Stimulate a Protective CD8 T Cell Response in Infection by Histoplasma capsulatum: Jr-Shiuan Lin, Chiao-Wen Yang, Dah-Wei Wang, and Betty A. Wu-Hsieh
J Immunol 2005 174: 6282-6291. [Abstract] [Full Text] [PDF]

Electroporation as a "Prime/Boost" Strategy for Naked DNA Vaccination against a Tumor Antigen: Sarah Buchan, Eirik Grønevik, Iacob Mathiesen, Catherine A. King, Freda K. Stevenson, and Jason Rice
J Immunol 2005 174: 6292-6298. [Abstract] [Full Text] [PDF]

Binding of the Complement Inhibitor C4bp to Serogroup B Neisseria meningitidis: Hanna Jarva, Sanjay Ram, Ulrich Vogel, Anna M. Blom, and Seppo Meri
J Immunol 2005 174: 6299-6307. [Abstract] [Full Text] [PDF]

The Mucosal Adjuvant Macrophage-Activating Lipopeptide-2 Directly Stimulates B Lymphocytes via the TLR2 without the Need of Accessory Cells: Stefan Borsutzky, Karsten Kretschmer, Pablo D. Becker, Peter F. Mühlradt, Carsten J. Kirschning, Siegfried Weiss, and Carlos A. Guzmán
J Immunol 2005 174: 6308-6313. [Abstract] [Full Text] [PDF]

Caspase-8 Activity Prevents Type 2 Cytokine Responses and Is Required for Protective T Cell-Mediated Immunity against Trypanosoma cruzi Infection: Elisabeth M. Silva, Landi V. C. Guillermo, Flávia L. Ribeiro-Gomes, Juliana De Meis, Renata M. S. Pereira, Zhengqi Wu, Teresa C. Calegari-Silva, Sérgio H. Seabra, Ulisses G. Lopes, Richard M. Siegel, George A. DosReis, and Marcela F. Lopes
J Immunol 2005 174: 6314-6321. [Abstract] [Full Text] [PDF]

Protein Kinase R Mediates Intestinal Epithelial Gene Remodeling in Response to Double-Stranded RNA and Live Rotavirus: Matam Vijay-Kumar, Jon R. Gentsch, William J. Kaiser, Niels Borregaard, Margaret K. Offermann, Andrew S. Neish, and Andrew T. Gewirtz
J Immunol 2005 174: 6322-6331. [Abstract] [Full Text] [PDF]

Exchanging ESAT6 with TB10.4 in an Ag85B Fusion Molecule-Based Tuberculosis Subunit Vaccine: Efficient Protection and ESAT6-Based Sensitive Monitoring of Vaccine Efficacy: Jes Dietrich, Claus Aagaard, Robert Leah, Anja W. Olsen, Anette Stryhn, T. Mark Doherty, and Peter Andersen
J Immunol 2005 174: 6332-6339. [Abstract] [Full Text] [PDF]

Control of Infection with Leishmania major in Susceptible BALB/c Mice Lacking the Common ${gamma}$ -Chain for FcR Is Associated with Reduced Production of IL-10 and TGF- ${beta}$ by Parasitized Cells: Udaikumar M. Padigel and Jay P. Farrell
J Immunol 2005 174: 6340-6345. [Abstract] [Full Text] [PDF]

Role of IFN- ${gamma}$ in Regulating T2 Immunity and the Development of Alternatively Activated Macrophages during Allergic Bronchopulmonary Mycosis: Shikha Arora, Yadira Hernandez, John R. Erb-Downward, Roderick A. McDonald, Galen B. Toews, and Gary B. Huffnagle
J Immunol 2005 174: 6346-6356. [Abstract] [Full Text] [PDF]

Cyclic AMP Response Element-Binding Protein Positively Regulates Production of IFN- ${gamma}$ by T Cells in Response to a Microbial Pathogen: Buka Samten, Susan T. Howard, Steven E. Weis, Shiping Wu, Homayoun Shams, James C. Townsend, Hassan Safi, and Peter F. Barnes
J Immunol 2005 174: 6357-6363. [Abstract] [Full Text] [PDF]

Insights into Pathogen Immune Evasion Mechanisms: Anaplasma phagocytophilum Fails to Induce an Apoptosis Differentiation Program in Human Neutrophils: Dori L. Borjesson, Scott D. Kobayashi, Adeline R. Whitney, Jovanka M. Voyich, Cynthia M. Argue, and Frank R. DeLeo
J Immunol 2005 174: 6364-6372. [Abstract] [Full Text] [PDF] Data Supplement

INFLAMMATION:

Gastrointestinal Ischemia-Reperfusion Injury Is Lectin Complement Pathway Dependent without Involving C1q: Melanie L. Hart, Kathleen A. Ceonzo, Lisa A. Shaffer, Kazue Takahashi, Russell P. Rother, Wende R. Reenstra, Jon A. Buras, and Gregory L. Stahl
J Immunol 2005 174: 6373-6380. [Abstract] [Full Text] [PDF]

Proteinase-3 Induces Procaspase-3 Activation in the Absence of Apoptosis: Potential Role of this Compartmentalized Activation of Membrane-Associated Procaspase-3 in Neutrophils: Magali Pederzoli, Chahrazade Kantari, Valérie Gausson, Sandra Moriceau, and Véronique Witko-Sarsat
J Immunol 2005 174: 6381-6390. [Abstract] [Full Text] [PDF]

Estradiol Is Required for a Proper Immune Response to Bacterial and Viral Pathogens in the Female Brain: Geneviève Soucy, Guy Boivin, Fernand Labrie, and Serge Rivest
J Immunol 2005 174: 6391-6398. [Abstract] [Full Text] [PDF]

Neutrophil-Derived Heparin-Binding Protein (HBP/CAP37) Deposited on Endothelium Enhances Monocyte Arrest under Flow Conditions: Oliver Soehnlein, Xun Xie, Holger Ulbrich, Ellinor Kenne, Pierre Rotzius, Hans Flodgaard, Einar E. Eriksson, and Lennart Lindbom
J Immunol 2005 174: 6399-6405. [Abstract] [Full Text] [PDF]

Junctional Adhesion Molecule-C Regulates the Early Influx of Leukocytes into Tissues during Inflammation: Michel Aurrand-Lions, Chrystelle Lamagna, John P. Dangerfield, Shijun Wang, Pedro Herrera, Sussan Nourshargh, and Beat A. Imhof
J Immunol 2005 174: 6406-6415. [Abstract] [Full Text] [PDF]

A Synthetic TLR4 Antagonist Has Anti-Inflammatory Effects in Two Murine Models of Inflammatory Bowel Disease: Madeline M. Fort, Afsaneh Mozaffarian, Axel G. Stöver, Jean da Silva Correia, David A. Johnson, R. Thomas Crane, Richard J. Ulevitch, David H. Persing, Helle Bielefeldt-Ohmann, Peter Probst, Eric Jeffery, Steven P. Fling, and Robert M. Hershberg
J Immunol 2005 174: 6416-6423. [Abstract] [Full Text] [PDF]

Regulation of c-Jun Phosphorylation by the I ${kappa}$ B Kinase- ${epsilon}$ Complex in Fibroblast-Like Synoviocytes: Susan E. Sweeney, Deepa Hammaker, David L. Boyle, and Gary S. Firestein
J Immunol 2005 174: 6424-6430. [Abstract] [Full Text] [PDF]

Questioning Current Concepts in Acute Pancreatitis: Endotoxin Contamination of Porcine Pancreatic Elastase Is Responsible for Experimental Pancreatitis-Associated Distant Organ Failure: Fabian Geisler, Hana Algül, Marc Riemann, and Roland M. Schmid
J Immunol 2005 174: 6431-6439. [Abstract] [Full Text] [PDF]

Exosomes Derived from IL-10-Treated Dendritic Cells Can Suppress Inflammation and Collagen-Induced Arthritis: Seon-Hee Kim, Eric R. Lechman, Nicole Bianco, Rajasree Menon, Annahita Keravala, Joan Nash, Zhibao Mi, Simon C. Watkins, Andrea Gambotto, and Paul D. Robbins
J Immunol 2005 174: 6440-6448. [Abstract] [Full Text] [PDF]

Role of Lipoteichoic Acid in the Phagocyte Response to Group B Streptococcus: Philipp Henneke, Siegfried Morath, Satoshi Uematsu, Stefan Weichert, Markus Pfitzenmaier, Osamu Takeuchi, Andrea Müller, Claire Poyart, Shizuo Akira, Reinhard Berner, Giuseppe Teti, Armin Geyer, Thomas Hartung, Patrick Trieu-Cuot, Dennis L. Kasper, and Douglas T. Golenbock
J Immunol 2005 174: 6449-6455. [Abstract] [Full Text] [PDF]

A Critical Role for Sphingosine Kinase in Anaphylatoxin-Induced Neutropenia, Peritonitis, and Cytokine Production in Vivo: Liudmila Pietrovna Vlasenko and Alirio J. Melendez
J Immunol 2005 174: 6456-6461. [Abstract] [Full Text] [PDF]

A Direct Role for C1 Inhibitor in Regulation of Leukocyte Adhesion: Shenghe Cai, Vandana S. Dole, Wolfgang Bergmeier, Jennifer Scafidi, Hanping Feng, Denisa D. Wagner, and Alvin E. Davis, III
J Immunol 2005 174: 6462-6466. [Abstract] [Full Text] [PDF]

TLR4, but Not TLR2, Signals Autoregulatory Apoptosis of Cultured Microglia: A Critical Role of IFN- ${beta}$ as a Decision Maker: Dae Young Jung, Heasuk Lee, Bo-Young Jung, Jiyeon Ock, Myung-Shik Lee, Won-Ha Lee, and Kyoungho Suk
J Immunol 2005 174: 6467-6476. [Abstract] [Full Text] [PDF]

CLINICAL IMMUNOLOGY:

Human Lymphoid and Myeloid Cell Development in NOD/LtSz-scid IL2R ${gamma}$ ^null Mice Engrafted with Mobilized Human Hemopoietic Stem Cells: Leonard D. Shultz, Bonnie L. Lyons, Lisa M. Burzenski, Bruce Gott, Xiaohua Chen, Stanley Chaleff, Malak Kotb, Stephen D. Gillies, Marie King, Julie Mangada, Dale L. Greiner, and Rupert Handgretinger
J Immunol 2005 174: 6477-6489. [Abstract] [Full Text] [PDF]

Activation of Discoidin Domain Receptor 1 on CD14-Positive Bronchoalveolar Lavage Fluid Cells Induces Chemokine Production in Idiopathic Pulmonary Fibrosis: Wataru Matsuyama, Masaki Watanabe, Yuko Shirahama, Ken-ichi Oonakahara, Ikkou Higashimoto, Teizo Yoshimura, Mitsuhiro Osame, and Kimiyoshi Arimura
J Immunol 2005 174: 6490-6498. [Abstract] [Full Text] [PDF]

Absence of Recipient CCR5 Promotes Early and Increased Allospecific Antibody Responses to Cardiac Allografts: Hiroyuki Amano, Alice Bickerstaff, Charles G. Orosz, Andrew C. Novick, Hiroshi Toma, and Robert L. Fairchild
J Immunol 2005 174: 6499-6508. [Abstract] [Full Text] [PDF]

Human 60-kDa Heat Shock Protein Is a Target Autoantigen of T Cells Derived from Atherosclerotic Plaques: Marisa Benagiano, Mario M. D’Elios, Amedeo Amedei, Annalisa Azzurri, Ruurd van der Zee, Alessandra Ciervo, Gianni Rombolà, Sergio Romagnani, Antonio Cassone, and Gianfranco Del Prete
J Immunol 2005 174: 6509-6517. [Abstract] [Full Text] [PDF]

Nucleotide-Binding Oligomerization Domain-2 Modulates Specific TLR Pathways for the Induction of Cytokine Release: Mihai G. Netea, Gerben Ferwerda, Dirk J. de Jong, Trees Jansen, Liesbeth Jacobs, Matthijs Kramer, Ton H. J. Naber, Joost P. H. Drenth, Stephen E. Girardin¶, Bart Jan Kullberg, Gosse J. Adema, and Jos W. M. Van der Meer
J Immunol 2005 174: 6518-6523. [Abstract] [Full Text] [PDF]

Gene Transfer of Tissue Inhibitor of Metalloproteinases-3 Reverses the Inhibitory Effects of TNF- ${alpha}$ on Fas-Induced Apoptosis in Rheumatoid Arthritis Synovial Fibroblasts: Andreas Drynda, Paul H. A. Quax, Manfred Neumann, Willemijn H. van der Laan, Géza Pap, Susanne Drynda, Ingmar Meinecke, Joern Kekow, Wolfram Neumann, Tom W. J. Huizinga, Michael Naumann, Wolfgang König, and Thomas Pap
J Immunol 2005 174: 6524-6531. [Abstract] [Full Text] [PDF]

Hepatitis C Virus Drives the Unconstrained Monoclonal Expansion of V_H1–69-Expressing Memory B Cells in Type II Cryoglobulinemia: A Model of Infection-Driven Lymphomagenesis: Maurizio Carbonari, Elisabetta Caprini, Tiziana Tedesco, Francesca Mazzetta, Valeria Tocco, Milvia Casato, Giandomenico Russo, and Massimo Fiorilli
J Immunol 2005 174: 6532-6539. [Abstract] [Full Text] [PDF]

Comparison of Killer Ig-Like Receptor Genotyping and Phenotyping for Selection of Allogeneic Blood Stem Cell Donors: Wing Leung, Rekha Iyengar, Brandon Triplett, Victoria Turner, Frederick G. Behm, Marti S. Holladay, James Houston, and Rupert Handgretinger
J Immunol 2005 174: 6540-6545. [Abstract] [Full Text] [PDF]