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On the cover: An eye section of a double-transgenic mouse expressing hen egg lysozyme (HEL) in the lens and thymus and HEL-specific TCR ("3A9") on T cells. Local accumulation of lymphoid cells in the limbus (arrow) and around retinal blood vessels (arrowhead). Zhang et al. T cell tolerance to a neo-self antigen expressed by thymic epithelial cells: the soluble form is more effective than the membrane-bound form. J. Immunol. 170:3954.)
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