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On the cover: Confocal image of a human neutrophil undergoing respiratory burst. The characteristically polylobed nucleus (blue) of the neutrophil is surrounded by Rac GTPase (red) and p22phox (green). The NADPH oxidase complex is assembled and activated intracellularly, shown as regions of yellow, where Rac and p22phox proteins colocalize. Lacy et al. Divergence of mechanisms regulating respiratory burst in blood and sputum eosinophils and neutrophils from atopic subjects. J. Immunol. 170:2670.)
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