CUTTING EDGE:

Cutting Edge: Impaired Toll-Like Receptor Expression and Function in Aging

Mary Renshaw, Julie Rockwell, Carrie Engleman, Andrew Gewirtz, Jacqueline Katz, and Suryaprakash Sambhara
J Immunol 2002 169: 4697-4701. [Abstract] [Full Text] [PDF]  

Cutting Edge: Localization of the Host Recognition Functions of Complement Factor H at the Carboxyl-Terminal: Implications for Hemolytic Uremic Syndrome

Michael K. Pangburn
J Immunol 2002 169: 4702-4706. [Abstract] [Full Text] [PDF]  

Cutting Edge: Tyk2 Is Required for the Induction and Nuclear Translocation of Daxx Which Regulates IFN--Induced Suppression of B Lymphocyte Formation

Kazuya Shimoda, Kenjirou Kamesaki, Akihiko Numata, Kenichi Aoki, Tadashi Matsuda, Kenji Oritani, Sadafumi Tamiya, Kouji Kato, Ken Takase, Rie Imamura, Tetsuya Yamamoto, Toshihiro Miyamoto, Koji Nagafuji, Hisashi Gondo, Seiho Nagafuchi, Kei-Ichi Nakayama, and Mine Harada
J Immunol 2002 169: 4707-4711. [Abstract] [Full Text] [PDF]  

Cutting Edge: CD4⁺CD25⁺ Regulatory T Cells Suppress Antigen-Specific Autoreactive Immune Responses and Central Nervous System Inflammation During Active Experimental Autoimmune Encephalomyelitis

Adam P. Kohm, Pamela A. Carpentier, Holly A. Anger, and Stephen D. Miller
J Immunol 2002 169: 4712-4716. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Most Murine CD8⁺ Intestinal Intraepithelial Lymphocytes Are Partially But Not Fully Activated T Cells

Heuy-Ching Wang, Qin Zhou, Jolene Dragoo, and John R. Klein
J Immunol 2002 169: 4717-4722. [Abstract] [Full Text] [PDF]  

T Cell Hyporesponsiveness Induced by Oral Administration of Ovalbumin Is Associated with Impaired NFAT Nuclear Translocation and p27^kip1 Degradation

Kazumi Asai, Satoshi Hachimura, Motoko Kimura, Terumasa Toraya, Masakatsu Yamashita, Toshinori Nakayama, and Shuichi Kaminogawa
J Immunol 2002 169: 4723-4731. [Abstract] [Full Text] [PDF]  

Effect of IL-12 on TNF--Mediated Osteoclast Formation in Bone Marrow Cells: Apoptosis Mediated by Fas/Fas Ligand Interaction

Hideki Kitaura, Noriko Nagata, Yuji Fujimura, Hitoshi Hotokezaka, Noriaki Yoshida, and Koji Nakayama
J Immunol 2002 169: 4732-4738. [Abstract] [Full Text] [PDF]  

TRAIL: A Mechanism of Tumor Surveillance in an Immune Privileged Site

Hae-ock Lee, John M. Herndon, Ramon Barreiro, Thomas S. Griffith, and Thomas A. Ferguson
J Immunol 2002 169: 4739-4744. [Abstract] [Full Text] [PDF]  

Histidine-Rich Glycoprotein Binds to DNA and FcRI and Potentiates the Ingestion of Apoptotic Cells by Macrophages

Nick N. Gorgani, Brian A. Smith, Dwight H. Kono, and Argyrios N. Theofilopoulos
J Immunol 2002 169: 4745-4751. [Abstract] [Full Text] [PDF]  

Allelic Variation in the Ectodomain of the Inhibitory Ly-49G2 Receptor Alters Its Specificity for Allogeneic and Xenogeneic Ligands

Elizabeth T. Silver, Kerry J. Lavender, Dong-Er Gong, Bart Hazes, and Kevin P. Kane
J Immunol 2002 169: 4752-4760. [Abstract] [Full Text] [PDF]  

Clonal Deletion of Simian Virus 40 Large T Antigen-Specific T Cells in the Transgenic Adenocarcinoma of Mouse Prostate Mice: An Important Role for Clonal Deletion in Shaping the Repertoire of T Cells Specific for Antigens Overexpressed in Solid Tumors

Xincheng Zheng, Jian-Xin Gao, Huiming Zhang, Terrence L. Geiger, Yang Liu, and Pan Zheng
J Immunol 2002 169: 4761-4769. [Abstract] [Full Text] [PDF]  

CD1 Molecules Efficiently Present Antigen in Immature Dendritic Cells and Traffic Independently of MHC Class II During Dendritic Cell Maturation

Xiaochun Cao, Masahiko Sugita, Nicole van der Wel, Jean Lai, Rick A. Rogers, Peter J. Peters, and Michael B. Brenner
J Immunol 2002 169: 4770-4777. [Abstract] [Full Text] [PDF]  

Containment of Simian Immunodeficiency Virus Infection in Vaccinated Macaques: Correlation with the Magnitude of Virus-Specific Pre- and Postchallenge CD4⁺ and CD8⁺ T Cell Responses

Zdenek Hel, Janos Nacsa, Elzbieta Tryniszewska, Wen-Po Tsai, Robyn Washington Parks, David C. Montefiori, Barbara K. Felber, James Tartaglia, George N. Pavlakis, and Genoveffa Franchini
J Immunol 2002 169: 4778-4787. [Abstract] [Full Text] [PDF]  

Long-Lived Th2 Memory in Experimental Allergic Asthma

Nazanin Mojtabavi, Gerhard Dekan, Georg Stingl, and Michelle M. Epstein
J Immunol 2002 169: 4788-4796. [Abstract] [Full Text] [PDF]  

T Cell Requirement for Development of Chronic Ulcerative Dermatitis in E- and P-Selectin-Deficient Mice

S. Bradley Forlow, E. James White, Kennard L. Thomas, Gregory J. Bagby, Patricia L. Foley, and Klaus Ley
J Immunol 2002 169: 4797-4804. [Abstract] [Full Text] [PDF]  

Caspase-Independent Phosphatidylserine Exposure During Apoptosis of Primary T Lymphocytes

Carole Ferraro-Peyret, Laurence Quemeneur, Monique Flacher, Jean-Pierre Revillard, and Laurent Genestier
J Immunol 2002 169: 4805-4810. [Abstract] [Full Text] [PDF]  

Tumor-Induced L-Selectin^high Suppressor T Cells Mediate Potent Effector T Cell Blockade and Cause Failure of Otherwise Curative Adoptive Immunotherapy

Liaomin Peng, Jørgen Kjaergäard, Gregory E. Plautz, Mohamed Awad, Judith A. Drazba, Suyu Shu, and Peter A. Cohen
J Immunol 2002 169: 4811-4821. [Abstract] [Full Text] [PDF]  

Regulatory Effect of IFN-, A Novel Type I IFN, On Cytokine Production by Cells of the Innate Immune System

Bernardetta Nardelli, Liubov Zaritskaya, Mark Semenuk, Yun Hee Cho, David W. LaFleur, Devanshi Shah, Stephen Ullrich, Giampiero Girolomoni, Cristina Albanesi, and Paul A. Moore
J Immunol 2002 169: 4822-4830. [Abstract] [Full Text] [PDF]  

CD4-Dependent Generation of Dominant Transplantation Tolerance Induced by Simultaneous Perturbation of CD154 and LFA-1 Pathways

Mark R. Nicolls, Marilyne Coulombe, Joshua Beilke, H. Carl Gelhaus, and Ronald G. Gill
J Immunol 2002 169: 4831-4839. [Abstract] [Full Text] [PDF]  

High-Affinity HLA-A(*)02.01 Peptides from Parathyroid Hormone-Related Protein Generate In Vitro and In Vivo Antitumor CTL Response Without Autoimmune Side Effects

Guido Francini, Antonio Scardino, Kostas Kosmatopoulos, François A. Lemonnier, Giuseppe Campoccia, Marianna Sabatino, Daniele Pozzessere, Roberto Petrioli, Luisa Lozzi, Paolo Neri, Giuseppe Fanetti, Maria Grazia Cusi, and Pierpaolo Correale
J Immunol 2002 169: 4840-4849. [Abstract] [Full Text] [PDF]  

Homeostasis of Peripheral CD4⁺ T Cells: IL-2R and IL-2 Shape a Population of Regulatory Cells That Controls CD4⁺ T Cell Numbers

Afonso R. M. Almeida, Nicolas Legrand, Martine Papiernik, and António A. Freitas
J Immunol 2002 169: 4850-4860. [Abstract] [Full Text] [PDF]  

Monocyte Chemoattractant Protein-1 Selectively Inhibits the Acquisition of CD40 Ligand-Dependent IL-12-Producing Capacity of Monocyte-Derived Dendritic Cells and Modulates Th1 Immune Response

Nemuko Omata, Motoko Yasutomi, Akiko Yamada, Hiromichi Iwasaki, Mitsufumi Mayumi, and Yusei Ohshima
J Immunol 2002 169: 4861-4866. [Abstract] [Full Text] [PDF]  

Reduction of Antiviral CD8 Lymphocytes In Vivo with Dendritic Cells Expressing Fas Ligand—Increased Survival of Viral (Lymphocytic Choriomeningitis Virus) Central Nervous System Infection

Tom Wolfe, Chrystelle Asseman, Anna Hughes, Hiroyuki Matsue, Akira Takashima, and Matthias G. von Herrath
J Immunol 2002 169: 4867-4872. [Abstract] [Full Text] [PDF]  

The Role of the Ets2 Transcription Factor in the Proliferation, Maturation, and Survival of Mouse Thymocytes

Arnaud Zaldumbide, Françoise Carlotti, Philippe Pognonec, and Kim E. Boulukos
J Immunol 2002 169: 4873-4881. [Abstract] [Full Text] [PDF]  

4-1BB Promotes the Survival of CD8⁺ T Lymphocytes by Increasing Expression of Bcl-x_L and Bfl-1

Hyeon-Woo Lee, Su-Jung Park, Beom K. Choi, Hyun Hwa Kim, Kyung-Ok Nam, and Byoung S. Kwon
J Immunol 2002 169: 4882-4888. [Abstract] [Full Text] [PDF]  

DNA Vaccination Breaks Tolerance for a Neo-Self Antigen in Liver: A Transgenic Murine Model of Autoimmune Hepatitis

Idriss Djilali-Saiah, Pascal Lapierre, Susana Vittozi, and Fernando Alvarez
J Immunol 2002 169: 4889-4896. [Abstract] [Full Text] [PDF]  

CD28, TNF Receptor, and IL-12 Are Critical for CD4-Independent Cross-Priming of Therapeutic Antitumor CD8⁺ T Cells

Hong-Ming Hu, Hauke Winter, Jun Ma, Michael Croft, Walter J. Urba, and Bernard A. Fox
J Immunol 2002 169: 4897-4904. [Abstract] [Full Text] [PDF]  

Highly Immunogenic and Totally Synthetic Lipopeptides as Self-Adjuvanting Immunocontraceptive Vaccines

Weiguang Zeng, Souravi Ghosh, Yuk Fai Lau, Lorena E. Brown, and David C. Jackson
J Immunol 2002 169: 4905-4912. [Abstract] [Full Text] [PDF]  

Positive Selection by the Pre-TCR Yields Mature CD8⁺ T Cells

Yuriko Ito, Satoko Arai, Nicolai S. C. van Oers, Iannis Aifantis, Harald von Boehmer, and Toru Miyazaki
J Immunol 2002 169: 4913-4919. [Abstract] [Full Text] [PDF]  

Repertoire of Antibody Response in Bone Marrow and the Memory Response Are Differentially Affected in Aging Mice

Yi-Feng Lu and Jan Cerny
J Immunol 2002 169: 4920-4927. [Abstract] [Full Text] [PDF]  

Systemic Administration of IL-15 Augments the Antigen-Specific Primary CD8⁺ T Cell Response Following Vaccination with Peptide-Pulsed Dendritic Cells

Mark P. Rubinstein, Andre N. Kadima, Mohamed L. Salem, Christophe L. Nguyen, William E. Gillanders, and David J. Cole
J Immunol 2002 169: 4928-4935. [Abstract] [Full Text] [PDF]  

Quantitation of CD8⁺ T Cell Expansion, Memory, and Protective Immunity After Immunization with Peptide-Coated Dendritic Cells

Sara E. Hamilton and John T. Harty
J Immunol 2002 169: 4936-4944. [Abstract] [Full Text] [PDF]  

The Role of Fibroblasts in Thymocyte-Positive Selection

Mirjana Lilic, Fabio R. Santori, Eric G. Neilson, Alan B. Frey, and Stanislav Vukmanovic
J Immunol 2002 169: 4945-4950. [Abstract] [Full Text] [PDF]  

Efficient Priming of CD4⁺ and CD8⁺ T Cells by DNA Vaccination Depends on Appropriate Targeting of Sufficient Levels of Immunologically Relevant Antigen to Appropriate Processing Pathways

Catherine Rush, Tim Mitchell, and Paul Garside
J Immunol 2002 169: 4951-4960. [Abstract] [Full Text] [PDF]  

Single T Cell Receptor-Mediated Recognition of an Identical HIV-Derived Peptide Presented by Multiple HLA Class I Molecules

Takamasa Ueno, Hiroko Tomiyama, and Masafumi Takiguchi
J Immunol 2002 169: 4961-4969. [Abstract] [Full Text] [PDF]  

Bovine T Cell Subsets Express Distinct Patterns of Chemokine Responsiveness and Adhesion Molecules: A Mechanism for Tissue-Specific T Cell Subset Accumulation

Eric Wilson, Jodi F. Hedges, Eugene C. Butcher, Michael Briskin, and Mark A. Jutila
J Immunol 2002 169: 4970-4975. [Abstract] [Full Text] [PDF]  

Long-Term Maintenance of Virus-Specific Effector Memory CD8⁺ T Cells in the Lung Airways Depends on Proliferation

Robert J. Hogan, Linda S. Cauley, Kenneth H. Ely, Tres Cookenham, Alan D. Roberts, Jean W. Brennan, Simon Monard, and David L. Woodland
J Immunol 2002 169: 4976-4981. [Abstract] [Full Text] [PDF]  

The Immunosuppressive Agent 15-Deoxyspergualin Functions by Inhibiting Cell Cycle Progression and Cytokine Production Following Naive T Cell Activation

Hilda Holcombe, Ira Mellman, Charles A. Janeway, Jr., Kim Bottomly, and Bonnie N. Dittel
J Immunol 2002 169: 4982-4989. [Abstract] [Full Text] [PDF]  

Selective Delivery of Augmented IL-2 Receptor Signals to Responding CD8⁺ T Cells Increases the Size of the Acute Antiviral Response and of the Resulting Memory T Cell Pool

Laurence E. Cheng and Philip D. Greenberg
J Immunol 2002 169: 4990-4997. [Abstract] [Full Text] [PDF]  

Murine Neonatal CD4⁺ Lymph Node Cells Are Highly Deficient in the Development of Antigen-Specific Th1 Function in Adoptive Adult Hosts

Becky Adkins, Yurong Bu, and Patricia Guevara
J Immunol 2002 169: 4998-5004. [Abstract] [Full Text] [PDF]  

Defective T Cell Priming Associated with Aging Can Be Rescued by Signaling Through 4-1BB (CD137)

Pratima Bansal-Pakala and Michael Croft
J Immunol 2002 169: 5005-5009. [Abstract] [Full Text] [PDF]  

A Positive Regulatory Role for Suppressor of Cytokine Signaling 1 in IFN--Induced MHC Class II Expression in Fibroblasts

Subburaj Ilangumaran, Dina Finan, José La Rose, Jason Raine, Anna Silverstein, Paulo De Sepulveda, and Robert Rottapel
J Immunol 2002 169: 5010-5020. [Abstract] [Full Text] [PDF]  

Age-Dependent Defects in TCR-Triggered Cytoskeletal Rearrangement in CD4⁺ T Cells

Gonzalo G. Garcia and Richard A. Miller
J Immunol 2002 169: 5021-5027. [Abstract] [Full Text] [PDF]  

The ₂-Adrenergic Agonist Salbutamol Potentiates Oral Induction of Tolerance, Suppressing Adjuvant Arthritis and Antigen-Specific Immunity

Pieter M. Cobelens, Annemieke Kavelaars, Anne Vroon, Marion Ringeling, Ruurd van der Zee, Willem van Eden, and Cobi J. Heijnen
J Immunol 2002 169: 5028-5035. [Abstract] [Full Text] [PDF]  

Dynamic Association of CD45 with Detergent-Insoluble Microdomains in T Lymphocytes

Stuart D. Edmonds and Hanne L. Ostergaard
J Immunol 2002 169: 5036-5042. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Chemoattractant-Stimulated Rac Activation in Wild-Type and Rac2-Deficient Murine Neutrophils: Preferential Activation of Rac2 and Rac2 Gene Dosage Effect on Neutrophil Functions

Shijun Li, Akira Yamauchi, Christophe C. Marchal, Jason K. Molitoris, Lawrence A. Quilliam, and Mary C. Dinauer
J Immunol 2002 169: 5043-5051. [Abstract] [Full Text] [PDF]  

HLA-DR4 Molecules in Neuroendocrine Epithelial Cells Associate to a Heterogeneous Repertoire of Cytoplasmic and Surface Self Peptides

Aura Muntasell, Montserrat Carrascal, Laurence Serradell, Peter van Veelen, Frank Verreck, Frits Koning, Graça Raposo, Joaquín Abián, and Dolores Jaraquemada
J Immunol 2002 169: 5052-5060. [Abstract] [Full Text] [PDF]  

Transcriptional Regulation of the MHC Class II Trans-Activator (CIITA) Promoter III: Identification of a Novel Regulatory Region in the 5'-Untranslated Region and an Important Role for cAMP-Responsive Element Binding Protein 1 and Activating Transcription Factor-1 in CIITA-Promoter III Transcriptional Activation in B Lymphocytes

Nienke van der Stoep, Edwin Quinten, and Peter J. van den Elsen
J Immunol 2002 169: 5061-5071. [Abstract] [Full Text] [PDF]  

Cysteine Residues Required for the Attachment of the Light Chain in Human IgA2

Koteswara R. Chintalacharuvu, Li J. Yu, Nishant Bhola, Kunihiko Kobayashi, Christine Z. Fernandez, and Sherie L. Morrison
J Immunol 2002 169: 5072-5077. [Abstract] [Full Text] [PDF]  

Modulation of Gene Expression by the MHC Class II Transactivator

Uma M. Nagarajan, Alyssa Bushey, and Jeremy M. Boss
J Immunol 2002 169: 5078-5088. [Abstract] [Full Text] [PDF]  

Analysis of MHC Class II Antigen Processing by Quantitation of Peptides that Constitute Nested Sets

John D. Lippolis, Forest M. White, Jarrod A. Marto, Chance J. Luckey, Timothy N. J. Bullock, Jeffrey Shabanowitz, Donald F. Hunt, and Victor H. Engelhard
J Immunol 2002 169: 5089-5097. [Abstract] [Full Text] [PDF]  

The HLA Molecules DQA1*0501/B1*0201 and DQA1*0301/B1*0302 Share an Extensive Overlap in Peptide Binding Specificity

John Sidney, Marie-France del Guercio, Scott Southwood, and Alessandro Sette
J Immunol 2002 169: 5098-5108. [Abstract] [Full Text] [PDF]  

Structural Factors Contributing to DM Susceptibility of MHC Class II/Peptide Complexes

Michael P. Belmares, Robert Busch, Kai W. Wucherpfennig, Harden M. McConnell, and Elizabeth D. Mellins
J Immunol 2002 169: 5109-5117. [Abstract] [Full Text] [PDF]  

Killer Ig-Like Receptor Haplotype Analysis by Gene Content: Evidence for Genomic Diversity with a Minimum of Six Basic Framework Haplotypes, Each with Multiple Subsets

Katharine C. Hsu, Xiao-Rong Liu, Annamalai Selvakumar, Eric Mickelson, Richard J. O’Reilly, and Bo Dupont
J Immunol 2002 169: 5118-5129. [Abstract] [Full Text] [PDF]  

Ly-6 Superfamily Members Ly-6A/E, Ly-6C, and Ly-6I Recognize Two Potential Ligands Expressed by B Lymphocytes

David L. Pflugh, Stephen E. Maher, and Alfred L. M. Bothwell
J Immunol 2002 169: 5130-5136. [Abstract] [Full Text] [PDF]  

C-Terminal Cysteine Residues Determine the IgE Binding of Aspergillus fumigatus Allergen Asp f 2

Banani Banerjee, Viswanath P. Kurup, Paul A. Greenberger, Kevin J. Kelly, and Jordan N. Fink
J Immunol 2002 169: 5137-5144. [Abstract] [Full Text] [PDF]  

Tryptase Is Expressed in Multiple Human Tissues, and a Recombinant Form Has Proteolytic Activity

Hong-Wei Wang, H. Patrick McNeil, Ahsan Husain, Ke Liu, Nicodemus Tedla, Paul S. Thomas, Mark Raftery, Garry C. King, Zhao Yan Cai, and John E. Hunt
J Immunol 2002 169: 5145-5152. [Abstract] [Full Text] [PDF]  

The Structure of HLA-B8 Complexed to an Immunodominant Viral Determinant: Peptide-Induced Conformational Changes and a Mode of MHC Class I Dimerization

Lars Kjer-Nielsen, Craig S. Clements, Andrew G. Brooks, Anthony W. Purcell, Marcos R. Fontes, James McCluskey, and Jamie Rossjohn
J Immunol 2002 169: 5153-5160. [Abstract] [Full Text] [PDF]  

Interaction with Factor Associated with Neutral Sphingomyelinase Activation, a WD Motif-Containing Protein, Identifies Receptor for Activated C-Kinase 1 as a Novel Component of the Signaling Pathways of the p55 TNF Receptor

Anna Ewgenjewna Tcherkasowa, Sabine Adam-Klages, Marie-Luise Kruse, Katja Wiegmann, Sabine Mathieu, Waldemar Kolanus, Martin Krönke, and Dieter Adam
J Immunol 2002 169: 5161-5170. [Abstract] [Full Text] [PDF]  

Increasing the Affinity of a Human IgG1 for the Neonatal Fc Receptor: Biological Consequences

William F. Dall’ Acqua, Robert M. Woods, E. Sally Ward, Susan R. Palaszynski, Nita K. Patel, Yambasu A. Brewah, Herren Wu, Peter A. Kiener, and Solomon Langermann
J Immunol 2002 169: 5171-5180. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Critical Role of Mitochondrial Damage in Determining Outcome of Macrophage Infection with Mycobacterium tuberculosis

Lei Duan, Huixian Gan, David E. Golan, and Heinz G. Remold
J Immunol 2002 169: 5181-5187. [Abstract] [Full Text] [PDF]  

Activated Intrahepatic Antigen-Presenting Cells Inhibit Hepatitis B Virus Replication in the Liver of Transgenic Mice

Kiminori Kimura, Kazuhiro Kakimi, Stefan Wieland, Luca G. Guidotti, and Francis V. Chisari
J Immunol 2002 169: 5188-5195. [Abstract] [Full Text] [PDF]  

Inhibition of HIV-1 Infection by Small Interfering RNA-Mediated RNA Interference

John Capodici, Katalin Karikó, and Drew Weissman
J Immunol 2002 169: 5196-5201. [Abstract] [Full Text] [PDF]  

Perforin-Mediated CTL Cytolysis Counteracts Direct Cell-Cell Spread of Listeria monocytogenes

Lani R. San Mateo, Ming Ming Chua, Susan R. Weiss, and Hao Shen
J Immunol 2002 169: 5202-5208. [Abstract] [Full Text] [PDF]  

Dysregulation of LPS-Induced Toll-Like Receptor 4-MyD88 Complex Formation and IL-1 Receptor-Associated Kinase 1 Activation in Endotoxin-Tolerant Cells

Andrei E. Medvedev, Arnd Lentschat, Larry M. Wahl, Douglas T. Golenbock, and Stefanie N. Vogel
J Immunol 2002 169: 5209-5216. [Abstract] [Full Text] [PDF]  

Induction of Specific Immune Responses by Polycation-Based Vaccines

Petra Lührs, Walter Schmidt, Raphaela Kutil, Michael Buschle, Stephan N. Wagner, Georg Stingl, and Achim Schneeberger
J Immunol 2002 169: 5217-5226. [Abstract] [Full Text] [PDF]  

Tumor Cell Lysate-Pulsed Dendritic Cells Are More Effective Than TCR Id Protein Vaccines for Active Immunotherapy of T Cell Lymphoma

Erin Gatza and Craig Y. Okada
J Immunol 2002 169: 5227-5235. [Abstract] [Full Text] [PDF]  

Lymphotoxin--Deficient Mice Make Delayed, But Effective, T and B Cell Responses to Influenza

Frances E. Lund, Santiago Partida-Sánchez, Byung O. Lee, Kimberly L. Kusser, Louise Hartson, Robert J. Hogan, David L. Woodland, and Troy D. Randall
J Immunol 2002 169: 5236-5243. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Secretion of Oncostatin M by Infiltrating Neutrophils: Regulation of IL-6 and Chemokine Expression in Human Mesothelial Cells

Suzanne M. Hurst, Rachel M. McLoughlin, James Monslow, Sara Owens, Llinos Morgan, Gerald M. Fuller, Nicholas Topley, and Simon A. Jones
J Immunol 2002 169: 5244-5251. [Abstract] [Full Text] [PDF]  

Platelet-Activating Factor Activates Two Distinct Effector Pathways in Human Eosinophils

Masahiko Kato, Hirokazu Kimura, Youichi Motegi, Atsushi Tachibana, Hisanori Minakami, Akihiro Morikawa, and Hirohito Kita
J Immunol 2002 169: 5252-5259. [Abstract] [Full Text] [PDF]  

Selective Suppression of Neutrophil Accumulation in Ongoing Pulmonary Inflammation by Systemic Inhibition of p38 Mitogen-Activated Protein Kinase

Jerry A. Nick, Scott K. Young, Patrick G. Arndt, Jonathan G. Lieber, Benjamin T. Suratt, Katie R. Poch, Natalie J. Avdi, Ken C. Malcolm, Christian Taube, Peter M. Henson, and G. Scott Worthen
J Immunol 2002 169: 5260-5269. [Abstract] [Full Text] [PDF]  

CD11b/CD18-Dependent Interactions of Neutrophils with Intestinal Epithelium Are Mediated by Fucosylated Proteoglycans

Ke Zen, Yuan Liu, Dana Cairo, and Charles A. Parkos
J Immunol 2002 169: 5270-5278. [Abstract] [Full Text] [PDF]  

Adenosine Up-Regulates Cyclooxygenase-2 in Human Granulocytes: Impact on the Balance of Eicosanoid Generation

Marc Pouliot, Marie-Élaine Fiset, Mireille Massé, Paul H. Naccache, and Pierre Borgeat
J Immunol 2002 169: 5279-5286. [Abstract] [Full Text] [PDF]  

NF-B and TNF-: A Positive Autocrine Loop in Human Lung Mast Cells?

William R. Coward, Yoshimichi Okayama, Hironori Sagara, Susan J. Wilson, Stephen T. Holgate, and Martin K. Church
J Immunol 2002 169: 5287-5293. [Abstract] [Full Text] [PDF]  

A Small Molecule Inhibitor of Redox-Regulated NF-B and Activator Protein-1 Transcription Blocks Allergic Airway Inflammation in a Mouse Asthma Model

William R. Henderson, Jr., Emil Y. Chi, Jia-Ling Teo, Cu Nguyen, and Michael Kahn
J Immunol 2002 169: 5294-5299. [Abstract] [Full Text] [PDF]  

Effect of Microbial Heat Shock Proteins on Airway Inflammation and Hyperresponsiveness

Yeong-Ho Rha, Christian Taube, Angela Haczku, Anthony Joetham, Katsuyuki Takeda, Catherine Duez, Marvin Siegel, M. Kemal Aydintug, Willi K. Born, Azzeddine Dakhama, and Erwin W. Gelfand
J Immunol 2002 169: 5300-5307. [Abstract] [Full Text] [PDF]  

Down-Regulation of Intestinal Lymphocyte Activation and Th1 Cytokine Production by Antibiotic Therapy in a Murine Model of Crohn’s Disease

Giorgos Bamias, Marco Marini, Christopher A. Moskaluk, Masaru Odashima, William G. Ross, Jesús Rivera-Nieves, and Fabio Cominelli
J Immunol 2002 169: 5308-5314. [Abstract] [Full Text] [PDF]  

Protease-Activated Receptor 2 Mediates Eosinophil Infiltration and Hyperreactivity in Allergic Inflammation of the Airway

Fabien Schmidlin, Silvia Amadesi, Karim Dabbagh, David E. Lewis, Patrick Knott, Nigel W. Bunnett, Paul R. Gater, Pierangelo Geppetti, Claude Bertrand, and Mary E. Stevens
J Immunol 2002 169: 5315-5321. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Prolonged Maturation and Enhanced Transduction of Dendritic Cells Migrated from Human Skin Explants After In Situ Delivery of CD40-Targeted Adenoviral Vectors

Tanja D. de Gruijl, Sylvia A. Luykx-de Bakker, Bryan W. Tillman, Alfons J. M. van den Eertwegh, Jan Buter, Sinéad M. Lougheed, Gerben J. van der Bij, A. Mahmoud Safer, Hidde J. Haisma, David T. Curiel, Rik J. Scheper, Herbert M. Pinedo, and Winald R. Gerritsen
J Immunol 2002 169: 5322-5331. [Abstract] [Full Text] [PDF]  

Delineation of Five Thyroglobulin T Cell Epitopes with Pathogenic Potential in Experimental Autoimmune Thyroiditis

Panayotis Verginis, Marianne M. Stanford, and George Carayanniotis
J Immunol 2002 169: 5332-5337. [Abstract] [Full Text] [PDF]  

TCR⁺ and CD161⁺ Thymocytes Express HIV-1 in the SCID-hu Mouse, Potentially Contributing to Immune Dysfunction in HIV Infection

Kevin B. Gurney, Otto O. Yang, S. Brian Wilson, and Christel H. Uittenbogaart
J Immunol 2002 169: 5338-5346. [Abstract] [Full Text] [PDF]  

Vaccination of Macaques with Long-Standing SIVmac251 Infection Lowers the Viral Set Point After Cessation of Antiretroviral Therapy

Elzbieta Tryniszewska, Janos Nacsa, Mark G. Lewis, Peter Silvera, David Montefiori, David Venzon, Zdenek Hel, Robyn Washington Parks, Marcin Moniuszko, Jim Tartaglia, Kendall A. Smith, and Genoveffa Franchini
J Immunol 2002 169: 5347-5357. [Abstract] [Full Text] [PDF]  

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