CUTTING EDGE:

Cutting Edge: C3, a Key Component of Complement Activation, Is Not Required for the Development of Myelin Oligodendrocyte Glycoprotein Peptide-Induced Experimental Autoimmune Encephalomyelitis in Mice

Divina M. Calida, Cris Constantinescu, Enkhmaa Purev, Guang-Xian Zhang, Elvira S. Ventura, Ehud Lavi, and Abdolmohamad Rostami
J Immunol 2001 166: 723-726. [Abstract] [Full Text] [PDF]  

Cutting Edge: Two Distinct Mechanisms Lead to Impaired T Cell Homeostasis in Janus Kinase 3- and CTLA-4-Deficient Mice

Sara Gozalo-Sanmillan, James M. McNally, Meei Y. Lin, Cynthia A. Chambers, and Leslie J. Berg
J Immunol 2001 166: 727-730. [Abstract] [Full Text] [PDF]  

Cutting Edge: Restoration of the Ability to Generate CTL in Mice Immune to Adenovirus by Delivery of Virus in a Collagen-Based Matrix

D. Robert Siemens, Bennett D. Elzey, David M. Lubaroff, Caitlin Bohlken, Robert J. Jensen, Axel Karl Swanson, and Timothy L. Ratliff
J Immunol 2001 166: 731-735. [Abstract] [Full Text] [PDF]  

Cutting Edge: Differential Sequestration of Plasma Membrane-Associated B Cell Antigen Receptor in Mature and Immature B Cells into Glycosphingolipid-Enriched Domains

James B. Chung, Mark A. Baumeister, and John G. Monroe
J Immunol 2001 166: 736-740. [Abstract] [Full Text] [PDF]  

Cutting Edge: Detection of Antigen-Specific CD4⁺ T Cells by HLA-DR1 Oligomers Is Dependent on the T Cell Activation State

Thomas O. Cameron, Jennifer R. Cochran, Bader Yassine-Diab, Rafick-Pierre Sékaly, and Lawrence J. Stern
J Immunol 2001 166: 741-745. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Regulation of the CTL Response by Macrophage Migration Inhibitory Factor

Riichiro Abe, Tina Peng, Joseph Sailors, Richard Bucala, and Christine N. Metz
J Immunol 2001 166: 747-753. [Abstract] [Full Text] [PDF]  

A Molecular Framework for Two-Step T Cell Signaling: Lck Src Homology 3 Mutations Discriminate Distinctly Regulated Lipid Raft Reorganization Events

Viresh P. Patel, Miriana Moran, Teresa A. Low, and M. Carrie Miceli
J Immunol 2001 166: 754-764. [Abstract] [Full Text] [PDF]  

The Restricted Expression of Granzyme M in Human Lymphocytes

Thomas J. Sayers, Alan D. Brooks, Jerrold M. Ward, Tomoaki Hoshino, William E. Bere, Gordon W. Wiegand, Janice M. Kelley, and Mark J. Smyth
J Immunol 2001 166: 765-771. [Abstract] [Full Text] [PDF]  

Mutation of the Hematopoietic Cell Phosphatase (Hcph) Gene Is Associated with Resistance to -Irradiation-Induced Apoptosis in Src Homology Protein Tyrosine Phosphatase (SHP)-1-Deficient "Motheaten" Mutant Mice

Hui-Chen Hsu, Leonard D. Shultz, Xiao Su, Jian Shi, Ping-Ar Yang, Melissa J. Relyea, Huang-Ge Zhang, and John D. Mountz
J Immunol 2001 166: 772-780. [Abstract] [Full Text] [PDF]  

Uterine Macrophages Express the gp49B Inhibitory Receptor in Midgestation

Yukie Matsumoto, Lawrence L. Wang, Wayne M. Yokoyama, and Takeshi Aso
J Immunol 2001 166: 781-786. [Abstract] [Full Text] [PDF]  

CD99 Regulates the Transport of MHC Class I Molecules from the Golgi Complex to the Cell Surface

Hae Won Sohn, Young Kee Shin, Im-Soon Lee, Young Mee Bae, Young Ho Suh, Min Kyung Kim, Tae Jin Kim, Kyeong Cheon Jung, Weon Seo Park, Chan-Sik Park, Doo Hyun Chung, Kwangseog Ahn, In Sun Kim, Young Hyeh Ko, Yung Jue Bang, Chul Woo Kim, and Seong Hoe Park
J Immunol 2001 166: 787-794. [Abstract] [Full Text] [PDF]  

Gene Expression in Antigen-Specific CD8⁺ T Cells During Viral Infection

Jason M. Grayson, Kaja Murali-Krishna, John D. Altman, and Rafi Ahmed
J Immunol 2001 166: 795-799. [Abstract] [Full Text] [PDF]  

Amino Acid Substitutions in the Putative MHC Class II "Dimer of Dimers" Interface Inhibit CD4⁺ T Cell Activation

Ragnar Lindstedt, Nicola Monk, Giovanna Lombardi, and Robert Lechler
J Immunol 2001 166: 800-808. [Abstract] [Full Text] [PDF]  

Positive and Negative Selection of Thymocytes Depends on Lck Interaction with the CD4 and CD8 Coreceptors

Patty A. Trobridge, Katherine A. Forbush, and Steven D. Levin
J Immunol 2001 166: 809-818. [Abstract] [Full Text] [PDF]  

Impairment of Mucosal Immunity by Total Parenteral Nutrition: Requirement for IgA in Murine Nasotracheal Anti-Influenza Immunity

Kathryn B. Renegar, Cheryl D. Johnson, R. Chance Dewitt, Brock K. King, Jian Li, Kazuhiko Fukatsu, and Kenneth A. Kudsk
J Immunol 2001 166: 819-825. [Abstract] [Full Text] [PDF]  

Soluble CD14 Mediates Efflux of Phospholipids from Cells

Tsuyoshi Sugiyama and Samuel D. Wright
J Immunol 2001 166: 826-831. [Abstract] [Full Text] [PDF]  

Salicylates Inhibit T Cell Adhesion on Endothelium Under Nonstatic Conditions: Induction of L-Selectin Shedding by a Tyrosine Kinase-Dependent Mechanism

Roberto Gerli, Paolo Gresele, Onelia Bistoni, Cristina Paolucci, Luisa Lanfrancone, Stefano Fiorucci, Christopher Muscat, and Vincenzo Costantini
J Immunol 2001 166: 832-840. [Abstract] [Full Text] [PDF]  

Role of CD40 in a T Cell-Mediated Negative Regulation of Ig Production

Laleh Majlessi and Guy Bordenave
J Immunol 2001 166: 841-847. [Abstract] [Full Text] [PDF]  

Stem Cell Factor and FLT3-Ligand Are Strictly Required to Sustain the Long-Term Expansion of Primitive CD34⁺DR^- Dendritic Cell Precursors

Antonio Curti, Miriam Fogli, Marina Ratta, Sante Tura, and Roberto M. Lemoli
J Immunol 2001 166: 848-854. [Abstract] [Full Text] [PDF]  

V_H Gene Replacement in Thymocytes

Rachel Golub, Denise Martin, Fred E. Bertrand, Marilia Cascalho, Matthias Wabl, and Gillian E. Wu
J Immunol 2001 166: 855-860. [Abstract] [Full Text] [PDF]  

Attenuation of Very Late Antigen-5-Mediated Adhesion of Bone Marrow-Derived Mast Cells to Fibronectin by Peptides with Inverted Hydropathy to EF-Hands

René Houtman, Robert Ten Broeke, J. Edwin Blalock, Matteo Villain, Andries S. Koster, and Frans P. Nijkamp
J Immunol 2001 166: 861-867. [Abstract] [Full Text] [PDF]  

Mast Cell-Dependent B and T Lymphocyte Activation Is Mediated by the Secretion of Immunologically Active Exosomes

Dimitris Skokos, Sophie Le Panse, Irène Villa, Jean-Claude Rousselle, Roger Peronet, Bernard David, Abdelkader Namane, and Salaheddine Mécheri
J Immunol 2001 166: 868-876. [Abstract] [Full Text] [PDF]  

CCR7 Expression and Memory T Cell Diversity in Humans

James J. Campbell, Kristine E. Murphy, Eric J. Kunkel, Christopher E. Brightling, Dulce Soler, Zhimin Shen, Judie Boisvert, Harry B. Greenberg, Mark A. Vierra, Stuart B. Goodman, Mark C. Genovese, Andrew J. Wardlaw, Eugene C. Butcher, and Lijun Wu
J Immunol 2001 166: 877-884. [Abstract] [Full Text] [PDF]  

Prostaglandin E₂ Suppressed IL-15-Mediated Human NK Cell Function Through Down-Regulation of Common -Chain

Pratibha C. Joshi, Xinchun Zhou, Marvin Cuchens, and Quintus Jones
J Immunol 2001 166: 885-891. [Abstract] [Full Text] [PDF]  

The Targeting of Somatic Hypermutation Closely Resembles That of Meiotic Mutation

Mihaela Oprea, Lindsay G. Cowell, and Thomas B. Kepler
J Immunol 2001 166: 892-899. [Abstract] [Full Text] [PDF]  

CD11b Expression Identifies CD8⁺CD28⁺ T Lymphocytes with Phenotype and Function of Both Naive/Memory and Effector Cells

Simona Fiorentini, Stefano Licenziati, Giulio Alessandri, Francesco Castelli, Silvio Caligaris, Monica Bonafede, Manuela Grassi, Emirena Garrafa, Andrea Balsari, Adolfo Turano, and Arnaldo Caruso
J Immunol 2001 166: 900-907. [Abstract] [Full Text] [PDF]  

Identification of MHC Class II-Restricted Peptide Ligands, Including a Glutamic Acid Decarboxylase 65 Sequence, that Stimulate Diabetogenic T Cells from Transgenic BDC2.5 Nonobese Diabetic Mice

Valeria Judkowski, Clemencia Pinilla, Kim Schroder, Lee Tucker, Nora Sarvetnick, and Darcy B. Wilson
J Immunol 2001 166: 908-917. [Abstract] [Full Text] [PDF]  

The Generation of Th Memory in Neonates Versus Adults: Prolonged Primary Th2 Effector Function and Impaired Development of Th1 Memory Effector Function in Murine Neonates

Becky Adkins, Yurong Bu, and Patricia Guevara
J Immunol 2001 166: 918-925. [Abstract] [Full Text] [PDF]  

Heterogeneity of the Memory CD4 T Cell Response: Persisting Effectors and Resting Memory T Cells

Mojgan Ahmadzadeh, S. Farzana Hussain, and Donna L. Farber
J Immunol 2001 166: 926-935. [Abstract] [Full Text] [PDF]  

Selective Blocking of Voltage-Gated K⁺ Channels Improves Experimental Autoimmune Encephalomyelitis and Inhibits T Cell Activation

Christine Beeton, Jocelyne Barbaria, Pierre Giraud, Jerome Devaux, Anne-Marie Benoliel, Maurice Gola, Jean Marc Sabatier, Dominique Bernard, Marcel Crest, and Evelyne Béraud
J Immunol 2001 166: 936-944. [Abstract] [Full Text] [PDF]  

IL-18 Enhances IL-4 Production by Ligand-Activated NKT Lymphocytes: A Pro-Th2 Effect of IL-18 Exerted Through NKT Cells

Maria C. Leite-de-Moraes, Agathe Hameg, Maria Pacilio, Yasuhiko Koezuka, Masaru Taniguchi, Luc Van Kaer, Elke Schneider, Michel Dy, and André Herbelin
J Immunol 2001 166: 945-951. [Abstract] [Full Text] [PDF]  

Induction of Anergy in Th1 Cells Associated with Increased Levels of Cyclin-Dependent Kinase Inhibitors p21^Cip1 and p27^{Kip1 1}

Stephanie K. Jackson, Annick DeLoose, and Kathleen M. Gilbert
J Immunol 2001 166: 952-958. [Abstract] [Full Text] [PDF]  

Vaccination with Allergen-IL-18 Fusion DNA Protects Against, and Reverses Established, Airway Hyperreactivity in a Murine Asthma Model

Holden T. Maecker, Gesine Hansen, David M. Walter, Rosemarie H. DeKruyff, Shoshana Levy, and Dale T. Umetsu
J Immunol 2001 166: 959-965. [Abstract] [Full Text] [PDF]  

The Serine/Threonine Phosphatase, PP2A: Endogenous Regulator of Inflammatory Cell Signaling

Thomas P. Shanley, Niti Vasi, Alvin Denenberg, and Hector R. Wong
J Immunol 2001 166: 966-972. [Abstract] [Full Text] [PDF]  

Quantifying the Frequency of Alloreactive T Cells In Vivo: New Answers to an Old Question

Elliot J. Suchin, Peter B. Langmuir, Ed Palmer, Mohamed H. Sayegh, Andrew D. Wells, and Laurence A. Turka
J Immunol 2001 166: 973-981. [Abstract] [Full Text] [PDF]  

Viral Infection Causes Rapid Sensitization to Lipopolysaccharide: Central Role of IFN-

Anneline Nansen and Allan Randrup Thomsen
J Immunol 2001 166: 982-988. [Abstract] [Full Text] [PDF]  

Different Programs of Activation-Induced Cell Death Are Triggered in Mature Activated CTL by Immunogenic and Partially Agonistic Peptide Ligands

Cheng-Hong Wei, Hideo Yagita, Maria G. Masucci, and Victor Levitsky
J Immunol 2001 166: 989-995. [Abstract] [Full Text] [PDF]  

Chemokine Receptor Expression and Function in CD4⁺ T Lymphocytes with Regulatory Activity

Silvia Sebastiani, Paola Allavena, Cristina Albanesi, Francesca Nasorri, Giancarlo Bianchi, Claudia Traidl, Silvano Sozzani, Giampiero Girolomoni, and Andrea Cavani
J Immunol 2001 166: 996-1002. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Negative Control of Store-Operated Ca²⁺ Influx by B Cell Receptor Cross-Linking

Akiko Hashimoto, Kenzo Hirose, Tomohiro Kurosaki, and Masamitsu Iino
J Immunol 2001 166: 1003-1008. [Abstract] [Full Text] [PDF]  

New Insights Into Endotoxin-Induced Activation of Macrophages: Involvement of a K⁺ Channel in Transmembrane Signaling

Rikard Blunck, Olaf Scheel, Mareike Müller, Klaus Brandenburg, Ulrike Seitzer, and Ulrich Seydel
J Immunol 2001 166: 1009-1015. [Abstract] [Full Text] [PDF]  

Quantitative and Qualitative Influences of Tapasin on the Class I Peptide Repertoire

Anthony W. Purcell, Jeffrey J. Gorman, Marína Garcia-Peydró, Alberto Paradela, Scott R. Burrows, Gert H. Talbo, Nihay Laham, Chen Au Peh, Eric C. Reynolds, José A. López de Castro, and James McCluskey
J Immunol 2001 166: 1016-1027. [Abstract] [Full Text] [PDF]  

Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Inhibit Expression of Fas Ligand in Activated T Lymphocytes by Regulating c-Myc, NF-B, NF-AT, and Early Growth Factors 2/3

Mario Delgado and Doina Ganea
J Immunol 2001 166: 1028-1040. [Abstract] [Full Text] [PDF]  

High Level Class II trans-Activator Induction Does Not Occur with Transient Activation of the IFN- Signaling Pathway

Donna D. Eason and George Blanck
J Immunol 2001 166: 1041-1048. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Histoplasma capsulatum Yeasts Are Phagocytosed Via Very Late Antigen-5, Killed, and Processed for Antigen Presentation by Human Dendritic Cells

Lucy A. Gildea, Randal E. Morris, and Simon L. Newman
J Immunol 2001 166: 1049-1056. [Abstract] [Full Text] [PDF]  

Bispecific Monoclonal Antibodies Mediate Binding of Dengue Virus to Erythrocytes in a Monkey Model of Passive Viremia

Chang S. Hahn, Olivia G. French, Patricia Foley, Edward N. Martin, and Ronald P. Taylor
J Immunol 2001 166: 1057-1065. [Abstract] [Full Text] [PDF]  

Lymphotoxin ^-/- Mice Develop Functionally Impaired CD8⁺ T Cell Responses and Fail to Contain Virus Infection of the Central Nervous System

Udayasankar Kumaraguru, Ila A. Davis, Shilpa Deshpande, Satvir S. Tevethia, and Barry T. Rouse
J Immunol 2001 166: 1066-1074. [Abstract] [Full Text] [PDF]  

Induction of a Novel Mechanism of Accelerated Bacterial Clearance by Lipopolysaccharide in CD14-Deficient and Toll-Like Receptor 4-Deficient Mice

Alain Haziot, Naoki Hijiya, Sophie C. Gangloff, Jack Silver, and Sanna M. Goyert
J Immunol 2001 166: 1075-1078. [Abstract] [Full Text] [PDF]  

Osteopontin Is a Negative Feedback Regulator of Nitric Oxide Synthesis in Murine Macrophages

Hongtao Guo, Charles Q. Cai, Rebecca A. Schroeder, and Paul C. Kuo
J Immunol 2001 166: 1079-1086. [Abstract] [Full Text] [PDF]  

A Cryptococcal Capsular Polysaccharide Mimotope Prolongs the Survival of Mice with Cryptococcus neoformans Infection

Richardson Fleuridor, Andrew Lees, and Liise-anne Pirofski
J Immunol 2001 166: 1087-1096. [Abstract] [Full Text] [PDF]  

Bystander Activation of CD8⁺ T Cells Contributes to the Rapid Production of IFN- in Response to Bacterial Pathogens

Ganjana Lertmemongkolchai, Guifang Cai, Christopher A. Hunter, and Gregory J. Bancroft
J Immunol 2001 166: 1097-1105. [Abstract] [Full Text] [PDF]  

Mucosal Delivery of a Respiratory Syncytial Virus CTL Peptide with Enterotoxin-Based Adjuvants Elicits Protective, Immunopathogenic, and Immunoregulatory Antiviral CD8⁺ T Cell Responses

Cameron P. Simmons, Tracy Hussell, Tim Sparer, Gerhard Walzl, Peter Openshaw, and Gordon Dougan
J Immunol 2001 166: 1106-1113. [Abstract] [Full Text] [PDF]  

Highly Conserved Regions of the Immunodominant Major Surface Protein 2 of the Genogroup II Ehrlichial Pathogen Anaplasma marginale Are Rich in Naturally Derived CD4⁺ T Lymphocyte Epitopes that Elicit Strong Recall Responses

Wendy C. Brown, Travis C. McGuire, Daming Zhu, Harris A. Lewin, Joshua Sosnow, and Guy H. Palmer
J Immunol 2001 166: 1114-1124. [Abstract] [Full Text] [PDF]  

Transcriptional Down-Regulation of CXC Chemokine Receptor 4 Induced by Impaired Association of Transcription Regulator YY1 with c-Myc in Human Herpesvirus 6-Infected Cells

Atsuhiko Hasegawa, Masaki Yasukawa, Ikuya Sakai, and Shigeru Fujita
J Immunol 2001 166: 1125-1131. [Abstract] [Full Text] [PDF]  

Variable Immunodominance Hierarchies for H2-M3-Restricted N-Formyl Peptides Following Bacterial Infection

Kristen M. Kerksiek, Dirk H. Busch, and Eric G. Pamer
J Immunol 2001 166: 1132-1140. [Abstract] [Full Text] [PDF]  

The Role of IL-10 in Promoting Disease Progression in Leishmaniasis

Margaret Mentink Kane and David M. Mosser
J Immunol 2001 166: 1141-1147. [Abstract] [Full Text] [PDF]  

Bacterial Invasion Augments Epithelial Cytokine Responses to Escherichia coli Through a Lipopolysaccharide-Dependent Mechanism

Joel D. Schilling, Matthew A. Mulvey, Carr D. Vincent, Robin G. Lorenz, and Scott J. Hultgren
J Immunol 2001 166: 1148-1155. [Abstract] [Full Text] [PDF]  

Complete Regression of Established Spontaneous Mammary Carcinoma and the Therapeutic Prevention of Genetically Programmed Neoplastic Transition by IL-12/Pulse IL-2: Induction of Local T Cell Infiltration, Fas/Fas Ligand Gene Expression, and Mammary Epithelial Apoptosis

Jon M. Wigginton, Jong-Wook Park, M. Eilene Gruys, Howard A. Young, Cheryl L. Jorcyk, Timothy C. Back, Michael J. Brunda, Robert M. Strieter, Jerrold Ward, Jeffrey E. Green, and Robert H. Wiltrout
J Immunol 2001 166: 1156-1168. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Nitric Oxide Synthase Inhibitors Have Opposite Effects on Acute Inflammation Depending on Their Route of Administration

Mark J. Paul-Clark, Derek W. Gilroy, Dean Willis, Derek A. Willoughby, and Annette Tomlinson
J Immunol 2001 166: 1169-1177. [Abstract] [Full Text] [PDF]  

Granulocyte-Macrophage Colony Stimulating Factor Up-Regulates CCR1 in Human Neutrophils

Sara S. Cheng, Joyce J. Lai, Nicholas W. Lukacs, and Steven L. Kunkel
J Immunol 2001 166: 1178-1184. [Abstract] [Full Text] [PDF]  

Cleavage of Mitogen-Activated Protein Kinases in Human Neutrophils Undergoing Apoptosis: Role in Decreased Responsiveness to Inflammatory Cytokines

Kenichi Suzuki, Taro Hasegawa, Chikahiko Sakamoto, Yue-Min Zhou, Fumihiko Hato, Masayuki Hino, Noriyuki Tatsumi, and Seiichi Kitagawa
J Immunol 2001 166: 1185-1192. [Abstract] [Full Text] [PDF]  

Role of C5a in Multiorgan Failure During Sepsis

Markus Huber-Lang, Vidya J. Sarma, Kristina T. Lu, Stephanie R. McGuire, Vaishalee A. Padgaonkar, Ren-Feng Guo, Ellen M. Younkin, Robin G. Kunkel, Jiabing Ding, Richard Erickson, John T. Curnutte, and Peter A. Ward
J Immunol 2001 166: 1193-1199. [Abstract] [Full Text] [PDF]  

Serum Amyloid P Component and C-Reactive Protein Mediate Phagocytosis Through Murine FcRs

Carolyn Mold, Hattie D. Gresham, and Terry W. Du Clos
J Immunol 2001 166: 1200-1205. [Abstract] [Full Text] [PDF]  

Protein Kinase C Phosphorylates a Subset of Selective Sites of the NADPH Oxidase Component p47^phox and Participates in Formyl Peptide-Mediated Neutrophil Respiratory Burst

Pham My-Chan Dang, Alexandre Fontayne, Jacques Hakim, Jamel El Benna, and Axel Périanin
J Immunol 2001 166: 1206-1213. [Abstract] [Full Text] [PDF]  

IL-4 Adenoviral Gene Therapy Reduces Inflammation, Proinflammatory Cytokines, Vascularization, and Bony Destruction in Rat Adjuvant-Induced Arthritis

James M. Woods, Kenneth J. Katschke, Jr., Michael V. Volin, Jeffrey H. Ruth, Drew C. Woodruff, M. Asif Amin, Matthew A. Connors, Hirokazu Kurata, Ken-Ichi Arai, G. Kenneth Haines, III, Pawan Kumar, and Alisa E. Koch
J Immunol 2001 166: 1214-1222. [Abstract] [Full Text] [PDF]  

Rac2 Is an Essential Regulator of Neutrophil Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation in Response to Specific Signaling Pathways

Chaekyun Kim and Mary C. Dinauer
J Immunol 2001 166: 1223-1232. [Abstract] [Full Text] [PDF]  

Rapid Up-Regulation of CXC Chemokines in the Airways after Ag-Specific CD4⁺ T Cell Activation

Patrick G. Knott, Paul R. Gater, Paul J. Dunford, Maria Elena Fuentes, and Claude P. Bertrand
J Immunol 2001 166: 1233-1240. [Abstract] [Full Text] [PDF]  

Hepatocyte Growth Factor Is a Regulator of Monocyte-Macrophage Function

Francesco Galimi, Erika Cottone, Elisa Vigna, Nicolò Arena, Carla Boccaccio, Silvia Giordano, Luigi Naldini, and Paolo M. Comoglio
J Immunol 2001 166: 1241-1247. [Abstract] [Full Text] [PDF]  

Flagellin, a Novel Mediator of Salmonella-Induced Epithelial Activation and Systemic Inflammation: IB Degradation, Induction of Nitric Oxide Synthase, Induction of Proinflammatory Mediators, and Cardiovascular Dysfunction

Tonyia Eaves-Pyles, Kanneganti Murthy, Lucas Liaudet, László Virág, Gary Ross, Francisco Garcia Soriano, Csaba Szabó, and Andrew L. Salzman
J Immunol 2001 166: 1248-1260. [Abstract] [Full Text] [PDF]  

Intratracheal Priming with Ovalbumin- and Ovalbumin 323–339 Peptide-Pulsed Dendritic Cells Induces Airway Hyperresponsiveness, Lung Eosinophilia, Goblet Cell Hyperplasia, and Inflammation

Sun-sang J. Sung, C. Edward Rose, Jr., and Shu Man Fu
J Immunol 2001 166: 1261-1271. [Abstract] [Full Text] [PDF]  

Actin Filaments Are Involved in the Regulation of Trafficking of Two Closely Related Chemokine Receptors, CXCR1 and CXCR2

Alon Zaslaver, Rotem Feniger-Barish, and Adit Ben-Baruch
J Immunol 2001 166: 1272-1284. [Abstract] [Full Text] [PDF]  

Neutral Endopeptidase Terminates Substance P-Induced Inflammation in Allergic Contact Dermatitis

Thomas E. Scholzen, Martin Steinhoff, Paola Bonaccorsi, Robin Klein, Silvia Amadesi, Piero Geppetti, Bao Lu, Norma P. Gerard, John E. Olerud, Thomas A. Luger, Nigel W. Bunnett, Eileen F. Grady, Cheryl A. Armstrong, and John C. Ansel
J Immunol 2001 166: 1285-1291. [Abstract] [Full Text] [PDF]  

B7/CD28 Costimulation Is Critical in Susceptibility to Pseudomonas aeruginosa Corneal Infection: A Comparative Study Using Monoclonal Antibody Blockade and CD28-Deficient Mice

Linda D. Hazlett, Sharon McClellan, Ronald Barrett, and Xiaowen Rudner
J Immunol 2001 166: 1292-1299. [Abstract] [Full Text] [PDF]  

TNF--Induced Expression of Adhesion Molecules in the Liver Is Under the Control of TNFR1—Relevance for Concanavalin A-Induced Hepatitis

Dominik Wolf, Rupert Hallmann, Gabriele Sass, Michael Sixt, Sabine Küsters, Bastian Fregien, Christian Trautwein, and Gisa Tiegs
J Immunol 2001 166: 1300-1307. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

A Deletion in the Gene Encoding the CD45 Antigen in a Patient with SCID

Elma Z. Tchilian, Diana L. Wallace, R. Spencer Wells, Darren R. Flower, Gareth Morgan, and Peter C. L. Beverley
J Immunol 2001 166: 1308-1313. [Abstract] [Full Text] [PDF]  

Roles of TNF-Related Apoptosis-Inducing Ligand in Experimental Autoimmune Encephalomyelitis

Brendan Hilliard, Andreas Wilmen, Cheryl Seidel, Tzu-Shang T. Liu, Rüdiger Göke, and Youhai Chen
J Immunol 2001 166: 1314-1319. [Abstract] [Full Text] [PDF]  

Thioether-Bonded Constructs of Fab' and Fc Modules Utilizing Differential Reduction of Interchain Disulfide Bonds

Kwok S. Kan, Valerie A. Anderson, Weng S. Leong, Andrew M. Smith, Andrew T. Worth, and George T. Stevenson
J Immunol 2001 166: 1320-1326. [Abstract] [Full Text] [PDF]  

Search for the Autoantibody Immunodominant Region on Thyroid Peroxidase: Epitopic Footprinting with a Human Monoclonal Autoantibody Locates a Facet on the Native Antigen Containing a Highly Conformational Epitope

Jin Guo, Xin-Min Yan, Sandra M. McLachlan, and Basil Rapoport
J Immunol 2001 166: 1327-1333. [Abstract] [Full Text] [PDF]  

Oligoclonal IgA Response in the Vascular Wall in Acute Kawasaki Disease

Anne H. Rowley, Stanford T. Shulman, Benjamin T. Spike, Carrie A. Mask, and Susan C. Baker
J Immunol 2001 166: 1334-1343. [Abstract] [Full Text] [PDF]  

Role of the CD95/CD95 Ligand System in Glucocorticoid-Induced Monocyte Apoptosis

Michael Schmidt, Norbert Lügering, Andreas Lügering, Hans-Gerd Pauels, Klaus Schulze-Osthoff, Wolfram Domschke, and Torsten Kucharzik
J Immunol 2001 166: 1344-1351. [Abstract] [Full Text] [PDF]  

Th1 to Th2 Cytokine Shifts in Nonobese Diabetic Mice: Sometimes an Outcome, Rather Than the Cause, of Diabetes Resistance Elicited by Immunostimulation

David V. Serreze, Harold D. Chapman, Cristina M. Post, Ellis A. Johnson, Wilma L. Suarez-Pinzon, and Alex Rabinovitch
J Immunol 2001 166: 1352-1359. [Abstract] [Full Text] [PDF]  

Anti-CD69 Autoantibodies Cross-React with Low Density Lipoprotein Receptor-Related Protein 2 in Systemic Autoimmune Diseases

Xiaohong Yu, Toshihiro Matsui, Masataka Otsuka, Taichi Sekine, Kazuhiko Yamamoto, Kusuki Nishioka, and Tomohiro Kato
J Immunol 2001 166: 1360-1369. [Abstract] [Full Text] [PDF]  

Type 1 Diabetes-Predisposing MHC Alleles Influence the Selection of Glutamic Acid Decarboxylase (GAD) 65-Specific T Cells in a Transgenic Model

Roshini S. Abraham, Li Wen, Eric V. Marietta, and Chella S. David
J Immunol 2001 166: 1370-1379. [Abstract] [Full Text] [PDF]  

HIV-1 Tat Protein Stimulates In Vivo Vascular Permeability and Lymphomononuclear Cell Recruitment

Marco Arese, Chiara Ferrandi, Luca Primo, Giovanni Camussi, and Federico Bussolino
J Immunol 2001 166: 1380-1388. [Abstract] [Full Text] [PDF]  

Overcoming T Cell Tolerance to the Hepatitis B Virus Surface Antigen in Hepatitis B Virus-Transgenic Mice

Alessandro D. Sette, Carla Oseroff, John Sidney, Jeff Alexander, Robert W. Chesnut, Kazuhiro Kakimi, Luca G. Guidotti, and Francis V. Chisari
J Immunol 2001 166: 1389-1397. [Abstract] [Full Text] [PDF]  

Both T Cells and NK Cells Inhibit the Engraftment of Xenogeneic Rat Bone Marrow Cells and the Induction of Xenograft Tolerance in Mice

Boris Nikolic, David T. Cooke, Guiling Zhao, and Megan Sykes
J Immunol 2001 166: 1398-1404. [Abstract] [Full Text] [PDF]  

Targeting Murine Immune Responses to Selected T Cell- or Antibody-Defined Determinants of the Hepatitis B Surface Antigen by Plasmid DNA Vaccines Encoding Chimeric Antigen

Reinhold Schirmbeck, Xin Zheng, Michael Roggendorf, Michael Geissler, Francis V. Chisari, Jörg Reimann, and Mengji Lu
J Immunol 2001 166: 1405-1413. [Abstract] [Full Text] [PDF]  

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