CUTTING EDGE:

Cutting Edge: Activation of HIV-1 Transcription by the MHC Class II Transactivator

Mohammed Saifuddin, Kenneth A. Roebuck, Cheong-hee Chang, Jenny P. Y. Ting, and Gregory T. Spear
J Immunol 2000 164: 3941-3945. [Abstract] [Full Text] [PDF]  

Cutting Edge: Infection by the Agent of Human Granulocytic Ehrlichiosis Prevents the Respiratory Burst by Down-Regulating gp91^phox

Rila Banerjee, Juan Anguita, Dirk Roos, and Erol Fikrig
J Immunol 2000 164: 3946-3949. [Abstract] [Full Text] [PDF]  

Cutting Edge: Increased Expression of Bcl-2 in Antigen-Specific Memory CD8⁺ T Cells

Jason M. Grayson, Allan J. Zajac, John D. Altman, and Rafi Ahmed
J Immunol 2000 164: 3950-3954. [Abstract] [Full Text] [PDF]  

Cutting Edge: Ectopic Expression of the Chemokine TCA4/SLC Is Sufficient to Trigger Lymphoid Neogenesis

Lian Fan, Christina R. Reilly, Yi Luo, Martin E. Dorf, and David Lo
J Immunol 2000 164: 3955-3959. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Differential Localization and Regulation of Death and Decoy Receptors for TNF-Related Apoptosis-Inducing Ligand (TRAIL) in Human Melanoma Cells

Xu Dong Zhang, Agustin V. Franco, Tam Nguyen, Christian P. Gray, and Peter Hersey
J Immunol 2000 164: 3961-3970. [Abstract] [Full Text] [PDF]  

Specific Subdomains of Vav Differentially Affect T Cell and NK Cell Activation

Daniel D. Billadeau, Stacy M. Mackie, Renee A. Schoon, and Paul J. Leibson
J Immunol 2000 164: 3971-3981. [Abstract] [Full Text] [PDF]  

Persistence of Physiological Self Antigen Is Required for the Regulation of Self Tolerance

Kristine M. Garza, Sally S. Agersborg, Elizabeth Baker, and Kenneth S. K. Tung
J Immunol 2000 164: 3982-3989. [Abstract] [Full Text] [PDF]  

Restoration of the Antibody Response to IgE/Antigen Complexes in CD23-Deficient Mice by CD23⁺ Spleen or Bone Marrow Cells

Susanne Gustavsson, Sara Wernersson, and Birgitta Heyman
J Immunol 2000 164: 3990-3995. [Abstract] [Full Text] [PDF]  

Distinct Requirements for C-C Chemokine and IL-2 Production by Naive, Previously Activated, and Anergic T Cells

Cara G. Lerner, Maureen R. Horton, Ronald H. Schwartz, and Jonathan D. Powell
J Immunol 2000 164: 3996-4002. [Abstract] [Full Text] [PDF]  

Sequences That Flank Subdominant and Cryptic Epitopes Influence the Proteolytic Generation of MHC Class I-Presented Peptides

Annie X. Y. Mo, Steven F. L. van Lelyveld, Abie Craiu, and Kenneth L. Rock
J Immunol 2000 164: 4003-4010. [Abstract] [Full Text] [PDF]  

Preferential Recognition of TCR Hypervariable Regions by Human Anti-Idiotypic T Cells Induced by T Cell Vaccination

Ying C. Q. Zang, Jian Hong, Victor M. Rivera, James Killian, and Jingwu Z. Zhang
J Immunol 2000 164: 4011-4017. [Abstract] [Full Text] [PDF]  

Engagement of CD28 Modulates CXC Chemokine Receptor 4 Surface Expression in Both Resting and CD3-Stimulated CD4⁺ T Cells

Paola Secchiero, Davide Zella, Sabrina Curreli, Prisco Mirandola, Silvano Capitani, Robert C. Gallo, and Giorgio Zauli
J Immunol 2000 164: 4018-4024. [Abstract] [Full Text] [PDF]  

The CC Chemokine CKß-11/MIP-3ß/ELC/Exodus 3 Mediates Tumor Rejection of Murine Breast Cancer Cells Through NK Cells

Stephen E. Braun, Keyue Chen, Richard G. Foster, Chang H. Kim, Robert Hromas, Mark H. Kaplan, Hal E. Broxmeyer, and Kenneth Cornetta
J Immunol 2000 164: 4025-4031. [Abstract] [Full Text] [PDF]  

CD95/Fas Signaling in T Lymphocytes Induces the Cell Cycle Control Protein p21^cip-1/WAF-1, Which Promotes Apoptosis

Ravi Hingorani, BaoYuan Bi, Tao Dao, Youngmee Bae, Akio Matsuzawa, and I. Nicholas Crispe
J Immunol 2000 164: 4032-4036. [Abstract] [Full Text] [PDF]  

Repeated Intratracheal Challenge with Particulate Antigen Modulates Murine Lung Cytokines ^,2

Jill Todt, Joanne Sonstein, Timothy Polak, Gerami D. Seitzman, Bin Hu, and Jeffrey L. Curtis
J Immunol 2000 164: 4037-4047. [Abstract] [Full Text] [PDF]  

Human NK Cells Express CC Chemokine Receptors 4 and 8 and Respond to Thymus and Activation-Regulated Chemokine, Macrophage-Derived Chemokine, and I-309

Marit Inngjerdingen, Bassam Damaj, and Azzam A. Maghazachi
J Immunol 2000 164: 4048-4054. [Abstract] [Full Text] [PDF]  

Fractalkine-Mediated Endothelial Cell Injury by NK Cells

Osamu Yoneda, Toshio Imai, Seiji Goda, Hiroshi Inoue, Akira Yamauchi, Toshio Okazaki, Hisao Imai, Osamu Yoshie, Eda T. Bloom, Naochika Domae, and Hisanori Umehara
J Immunol 2000 164: 4055-4062. [Abstract] [Full Text] [PDF]  

Differing Roles of Inflammation and Antigen in T Cell Proliferation and Memory Generation

Dirk H. Busch, Kristen M. Kerksiek, and Eric G. Pamer
J Immunol 2000 164: 4063-4070. [Abstract] [Full Text] [PDF]  

Caspase Enzyme Activity Is Not Essential for Apoptosis During Thymocyte Development

Petra Doerfler, Katherine A. Forbush, and Roger M. Perlmutter
J Immunol 2000 164: 4071-4079. [Abstract] [Full Text] [PDF]  

Contributions of CD8⁺ T Cells and Viral Spread to Demyelinating Disease

Norman W. Marten, Stephen A. Stohlman, Roscoe D. Atkinson, David R. Hinton, John O. Fleming, and Cornelia C. Bergmann
J Immunol 2000 164: 4080-4088. [Abstract] [Full Text] [PDF]  

Independent Functioning of Cytosolic Phospholipase A₂ and Phospholipase D₁ in Trp-Lys-Tyr-Met-Val-D-Met-Induced Superoxide Generation in Human Monocytes

Yoe-Sik Bae, Youndong Kim, Jae Ho Kim, Taehoon G. Lee, Yong Kim, Pann-Ghill Suh, and Sung Ho Ryu
J Immunol 2000 164: 4089-4096. [Abstract] [Full Text] [PDF]  

CD134L Engagement Enhances Human B Cell Ig Production: CD154/CD40, CD70/CD27, and CD134/CD134L Interactions Coordinately Regulate T Cell-Dependent B Cell Responses

Shinji Morimoto, Yumiko Kanno, Yuetsu Tanaka, Yoshiaki Tokano, Hiroshi Hashimoto, Serge Jacquot, Chikao Morimoto, Stuart F. Schlossman, Hideo Yagita, Ko Okumura, and Tetsuji Kobata
J Immunol 2000 164: 4097-4104. [Abstract] [Full Text] [PDF]  

LIGHT, a TNF-Like Molecule, Costimulates T Cell Proliferation and Is Required for Dendritic Cell-Mediated Allogeneic T Cell Response

Koji Tamada, Koji Shimozaki, Andrei I. Chapoval, Yifan Zhai, Jeffery Su, Su-Fang Chen, Shie-Liang Hsieh, Shigekazu Nagata, Jian Ni, and Lieping Chen
J Immunol 2000 164: 4105-4110. [Abstract] [Full Text] [PDF]  

Autoreactive B Cells Escape Clonal Deletion by Expressing Multiple Antigen Receptors

James J. Kenny, Louis J. Rezanka, Ana Lustig, Randy T. Fischer, Jeffrey Yoder, Shannon Marshall, and Dan L. Longo
J Immunol 2000 164: 4111-4119. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Sulfhydryl Regulation of L-Selectin Shedding: Phenylarsine Oxide Promotes Activation-Independent L-Selectin Shedding from Leukocytes

Teresa A. Bennett, Bruce S. Edwards, Larry A. Sklar, and Snezna Rogelj
J Immunol 2000 164: 4120-4129. [Abstract] [Full Text] [PDF]  

A Human CTL Recognizes a Caspase-8-Derived Peptide on Autologous HLA-B*3503 Molecules and Two Unrelated Peptides on Allogeneic HLA-B*3501 Molecules

Susanna Mandruzzato, Vincent Stroobant, Nathalie Demotte, and Pierre van der Bruggen
J Immunol 2000 164: 4130-4134. [Abstract] [Full Text] [PDF]  

Metabolism of Recombination Coding Ends in scid Cells

Matthew L. Brown and Yung Chang
J Immunol 2000 164: 4135-4142. [Abstract] [Full Text] [PDF]  

Methylation of Class II trans-Activator Promoter IV: A Novel Mechanism of MHC Class II Gene Control

Ann C. Morris, Wendi E. Spangler, and Jeremy M. Boss
J Immunol 2000 164: 4143-4149. [Abstract] [Full Text] [PDF]  

Perforin Lytic Activity Is Controlled by Calreticulin

Stephanie A. Fraser, Reza Karimi, Marek Michalak, and Dorothy Hudig
J Immunol 2000 164: 4150-4155. [Abstract] [Full Text] [PDF]  

Mass Spectrometric Characterization of a Discontinuous Epitope of the HIV Envelope Protein HIV-gp120 Recognized by the Human Monoclonal Antibody 1331A

Elisabeth O. Hochleitner, Miroslaw K. Gorny, Susan Zolla-Pazner, and Kenneth B. Tomer
J Immunol 2000 164: 4156-4161. [Abstract] [Full Text] [PDF]  

Human Anti-Thyroid Peroxidase Single-Chain Fragment Variable of Ig Isolated from a Combinatorial Library Assembled In-Cell: Insights into the In Vivo Situation

Nicolas Chapal, Sylvie Peraldi-Roux, Damien Bresson, Martine Pugniere, Jean-Claude Mani, Claude Granier, Line Baldet, Bernard Guerrier, Bernard Pau, and Majida Bouanani
J Immunol 2000 164: 4162-4169. [Abstract] [Full Text] [PDF]  

Six X-Linked Agammaglobulinemia-Causing Missense Mutations in the Src Homology 2 Domain of Bruton’s Tyrosine Kinase: Phosphotyrosine-Binding and Circular Dichroism Analysis

Pekka T. Mattsson, Ilkka Lappalainen, Carl-Magnus Bäckesjö, Eeva Brockmann, Susanna Laurén, Mauno Vihinen, and C. I. Edvard Smith
J Immunol 2000 164: 4170-4177. [Abstract] [Full Text] [PDF]  

Mapping of the C1q Binding Site on Rituxan, a Chimeric Antibody with a Human IgG1 Fc

Esohe E. Idusogie, Leonard G. Presta, Helene Gazzano-Santoro, Klara Totpal, Pin Yee Wong, Mark Ultsch, Y. Gloria Meng, and Michael G. Mulkerrin
J Immunol 2000 164: 4178-4184. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Haemophilus influenzae Stimulates ICAM-1 Expression on Respiratory Epithelial Cells

Annette G. Frick, Theresa D. Joseph, Liyi Pang, Autumn M. Rabe, Joseph W. St. Geme, III, and Dwight C. Look
J Immunol 2000 164: 4185-4196. [Abstract] [Full Text] [PDF]  

IL-9 Protects Mice from Gram-Negative Bacterial Shock: Suppression of TNF-, IL-12, and IFN-, and Induction of IL-10

Ursula Grohmann, Jacques Van Snick, Franca Campanile, Silvia Silla, Antonio Giampietri, Carmine Vacca, Jean-Cristophe Renauld, Maria C. Fioretti, and Paolo Puccetti
J Immunol 2000 164: 4197-4203. [Abstract] [Full Text] [PDF]  

Dendritic Cells Infected with a Vaccinia Vector Carrying the Human gp100 Gene Simultaneously Present Multiple Specificities and Elicit High-Affinity T Cells Reactive to Multiple Epitopes and Restricted by HLA-A2 and -A3

Sixun Yang, David Kittlesen, Craig L. Slingluff, Jr., Carol E. Vervaert, Hilliard F. Seigler, and Timothy L. Darrow
J Immunol 2000 164: 4204-4211. [Abstract] [Full Text] [PDF]  

Suppression of Endogenous IL-10 Gene Expression in Dendritic Cells Enhances Antigen Presentation for Specific Th1 Induction: Potential for Cellular Vaccine Development

Joseph U. Igietseme, Godwin A. Ananaba, Jacqueline Bolier, Samera Bowers, Terri Moore, Tesfaye Belay, Francis O. Eko, Deborah Lyn, and Carolyn M. Black
J Immunol 2000 164: 4212-4219. [Abstract] [Full Text] [PDF]  

Type I IFN Modulates Innate and Specific Antiviral Immunity

Joan E. Durbin, Ana Fernandez-Sesma, Chien-Kuo Lee, T. Dharma Rao, Alan B. Frey, Thomas M. Moran, Stanislav Vukmanovic, Adolfo García-Sastre, and David E. Levy
J Immunol 2000 164: 4220-4228. [Abstract] [Full Text] [PDF]  

Nitric Oxide Mediates Intestinal Pathology But Not Immune Expulsion During Trichinella spiralis Infection in Mice

Catherine E. Lawrence, Jacqueline C. M. Paterson, Xiao-Qing Wei, Foo Y. Liew, Paul Garside, and Malcolm W. Kennedy
J Immunol 2000 164: 4229-4234. [Abstract] [Full Text] [PDF]  

Ongoing Murine T1 or T2 Immune Responses to the Hepatitis B Surface Antigen Are Excluded from the Liver that Expresses Transgene-Encoded Hepatitis B Surface Antigen

Reinhold Schirmbeck, Jens Wild, Detlef Stober, Hubert E. Blum, Francis V. Chisari, Michael Geissler, and Jörg Reimann
J Immunol 2000 164: 4235-4243. [Abstract] [Full Text] [PDF]  

HLA-DQ Tetramers Identify Epitope-Specific T Cells in Peripheral Blood of Herpes Simplex Virus Type 2-Infected Individuals: Direct Detection of Immunodominant Antigen-Responsive Cells

William W. Kwok, Andrew W. Liu, Erik J. Novak, John A. Gebe, Ruth A. Ettinger, Gerald T. Nepom, Sigrid N. Reymond, and David M. Koelle
J Immunol 2000 164: 4244-4249. [Abstract] [Full Text] [PDF]  

IL-13-Mediated Worm Expulsion Is B7 Independent and IFN- Sensitive

Joseph Urban, Hui Fang, Qian Liu, Melinda J. Ekkens, Shen-Jue Chen, Diep Nguyen, Velia Mitro, Debra D. Donaldson, Colleen Byrd, Robert Peach, Suzanne C. Morris, Fred D. Finkelman, Lisa Schopf, and William C. Gause
J Immunol 2000 164: 4250-4256. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Synthetic Peptides of CD66a Stimulate Neutrophil Adhesion to Endothelial Cells

Keith M. Skubitz, Kenneth D. Campbell, and Amy P. N. Skubitz
J Immunol 2000 164: 4257-4264. [Abstract] [Full Text] [PDF]  

Cytokine-Stimulated, But Not HIV-Infected, Human Monocyte-Derived Macrophages Produce Neurotoxic Levels of L-Cysteine

Michael W. Yeh, Marcus Kaul, Jialin Zheng, Hans S. L. M. Nottet, Michael Thylin, Howard E. Gendelman, and Stuart A. Lipton
J Immunol 2000 164: 4265-4270. [Abstract] [Full Text] [PDF]  

Stem Cell Factor Plays a Major Role in the Recruitment of Eosinophils in Allergic Pleurisy in Mice Via the Production of Leukotriene B₄

Andre Klein, Andre Talvani, Denise C. Cara, Kenia L. Gomes, Nicholas W. Lukacs, and Mauro M. Teixeira
J Immunol 2000 164: 4271-4276. [Abstract] [Full Text] [PDF]  

TNF- Gene Expression in Macrophages: Regulation by NF-B Is Independent of c-Jun or C/EBPß

Hongtao Liu, Prodromos Sidiropoulos, Guobin Song, Lisa J. Pagliari, Michael J. Birrer, Bernd Stein, Josef Anrather, and Richard M. Pope
J Immunol 2000 164: 4277-4285. [Abstract] [Full Text] [PDF]  

Granulocyte-Macrophage Colony-Stimulating Factor Delays Neutrophil Constitutive Apoptosis Through Phosphoinositide 3-Kinase and Extracellular Signal-Regulated Kinase Pathways

Jon B. Klein, Madhavi J. Rane, Janice A. Scherzer, Patricia Y. Coxon, Ralph Kettritz, Jeanine M. Mathiesen, Abdul Buridi, and Kenneth R. McLeish
J Immunol 2000 164: 4286-4291. [Abstract] [Full Text] [PDF]  

Crucial Role of the Amino-Terminal Tyrosine Residue 42 and the Carboxyl-Terminal PEST Domain of IB in NF-B Activation by an Oxidative Stress

Sonia Schoonbroodt, Valérie Ferreira, Martin Best-Belpomme, Johan R. Boelaert, Sylvie Legrand-Poels, Marie Korner, and Jacques Piette
J Immunol 2000 164: 4292-4300. [Abstract] [Full Text] [PDF]  

IL-1 Receptor-Associated Kinase Modulates Host Responsiveness to Endotoxin

Jennifer L. Swantek, May F. Tsen, Melanie H. Cobb, and James A. Thomas
J Immunol 2000 164: 4301-4306. [Abstract] [Full Text] [PDF]  

Calcitonin Gene-Related Peptide Induces IL-8 Synthesis in Human Corneal Epithelial Cells

Mau T. Tran, Mary H. Ritchie, Robert N. Lausch, and John E. Oakes
J Immunol 2000 164: 4307-4312. [Abstract] [Full Text] [PDF]  

CX₃C-Chemokine, Fractalkine-Enhanced Adhesion of THP-1 Cells to Endothelial Cells Through Integrin-Dependent and -Independent Mechanisms

Seiji Goda, Toshio Imai, Osamu Yoshie, Osamu Yoneda, Hiroshi Inoue, Yutaka Nagano, Toshiro Okazaki, Hisao Imai, Eda T. Bloom, Naochika Domae, and Hisanori Umehara
J Immunol 2000 164: 4313-4320. [Abstract] [Full Text] [PDF]  

Kinase Pathways in Chemoattractant-Induced Degranulation of Neutrophils: The Role of p38 Mitogen-Activated Protein Kinase Activated by Src Family Kinases

Attila Mócsai, Zoltán Jakus, Tibor Vántus, Giorgio Berton, Clifford A. Lowell, and Erzsébet Ligeti
J Immunol 2000 164: 4321-4331. [Abstract] [Full Text] [PDF]  

Expression of a Functional High-Affinity IgG Receptor, FcRI, on Human Mast Cells: Up-Regulation by IFN-

Yoshimichi Okayama, Arnold S. Kirshenbaum, and Dean D. Metcalfe
J Immunol 2000 164: 4332-4339. [Abstract] [Full Text] [PDF]  

A Role for Complement in Antibody-Mediated Inflammation: C5-Deficient DBA/1 Mice Are Resistant to Collagen-Induced Arthritis

Yi Wang, Jane Kristan, Liming Hao, Catherine S. Lenkoski, Yamin Shen, and Louis A. Matis
J Immunol 2000 164: 4340-4347. [Abstract] [Full Text] [PDF]  

Neutrophil Tethering on E-Selectin Activates ß₂ Integrin Binding to ICAM-1 Through a Mitogen-Activated Protein Kinase Signal Transduction Pathway

Scott I. Simon, Yu Hu, Dietmar Vestweber, and C. Wayne Smith
J Immunol 2000 164: 4348-4358. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Presentation of B-Crystallin to T Cells in Active Multiple Sclerosis Lesions: An Early Event Following Inflammatory Demyelination

Jeffrey J. Bajramovic, Arianne C. Plomp, Annette van der Goes, Cindy Koevoets, Jia Newcombe, M. Louise Cuzner, and Johannes M. van Noort
J Immunol 2000 164: 4359-4366. [Abstract] [Full Text] [PDF]  

Mechanism for the Isotype Dependence of Antibody-Mediated Toxicity in Cryptococcus neoformans-Infected Mice

Nikoletta Lendvai, Xiao-Wu Qu, Wei Hsueh, and Arturo Casadevall
J Immunol 2000 164: 4367-4374. [Abstract] [Full Text] [PDF]  

Differential Expression of NK T Cell V24JQ Invariant TCR Chain in the Lesions of Multiple Sclerosis and Chronic Inflammatory Demyelinating Polyneuropathy

Zsolt Illés, Takayuki Kondo, Jia Newcombe, Nobuyuki Oka, Takeshi Tabira, and Takashi Yamamura
J Immunol 2000 164: 4375-4381. [Abstract] [Full Text] [PDF]  

A Tumor-Infiltrating Lymphocyte from a Melanoma Metastasis with Decreased Expression of Melanoma Differentiation Antigens Recognizes MAGE-12

Monica C. Panelli, Maria P. Bettinotti, Kate Lally, Galen A. Ohnmacht, Yong Li, Paul Robbins, Adam Riker, Steven A. Rosenberg, and Francesco M. Marincola
J Immunol 2000 164: 4382-4392. [Abstract] [Full Text] [PDF]  

Characterization of T Cell Responses to Hev b 3, an Allergen Associated with Latex Allergy in Spina Bifida Patients

Barbara Bohle, Birgit Wagner, Ute Vollmann, Dietke Buck, Bodo Niggemann, Zsolt Szépfalusi, Gottfried Fischer, Otto Scheiner, Heimo Breiteneder, and Christof Ebner
J Immunol 2000 164: 4393-4398. [Abstract] [Full Text] [PDF]  

CD30⁺ T Cells in Rheumatoid Synovitis: Mechanisms of Recruitment and Functional Role

Roberto Gerli, Costantino Pitzalis, Onelia Bistoni, Brunangelo Falini, Vincenzo Costantini, Anna Russano, and Claudio Lunardi
J Immunol 2000 164: 4399-4407. [Abstract] [Full Text] [PDF]  

Fine Mapping of IGAD1 in IgA Deficiency and Common Variable Immunodeficiency: Identification and Characterization of Haplotypes Shared by Affected Members of 101 Multiple-Case Families^,2

Igor Vorechovsky, Michael Cullen, Mary Carrington, Lennart Hammarström, and A. David B. Webster
J Immunol 2000 164: 4408-4416. [Abstract] [Full Text] [PDF]  

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