CUTTING EDGE:

Commentary: Conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/activatory counterparts

F Vely and E Vivier
J Immunol 1997 159: 2075-2077. [Abstract] [PDF]  

Induction of thymocyte deletion by purified single peptide/major histocompatibility complex ligands

S Lesage, J Charron, G Winslow, and P Hugo
J Immunol 1997 159: 2078-2081. [Abstract] [PDF]  

Protein kinase C alpha-mediated chronic signal transduction for immunosenescence

K Ohkusu, J Du, KI Isobe, H Yi, AA Akhand, M Kato, H Suzuki, H Hidaka, and I Nakashima
J Immunol 1997 159: 2082-2084. [Abstract] [PDF]  

ARTICLES:

Memory, but not naive, peripheral blood B lymphocytes differentiate into Ig-secreting cells after CD40 ligation and costimulation with IL-4 and the differentiation factors IL-2, IL-10, and IL-3

V Kindler and RH Zubler
J Immunol 1997 159: 2085-2090. [Abstract] [PDF]  

Perforin-dependent cytotoxic activity and lymphokine secretion by CD4+ T cells are regulated by CD8+ T cells

NS Williams and VH Engelhard
J Immunol 1997 159: 2091-2099. [Abstract] [PDF]  

Positive and negative selection of functional mouse CD4 cells by porcine MHC in pig thymus grafts

Y Zhao, JJ Sergio, K Swenson, JS Arn, DH Sachs, and M Sykes
J Immunol 1997 159: 2100-2107. [Abstract] [PDF]  

Human autoreactive and foreign antigen-specific T cells resist apoptosis induced by soluble recombinant CD95 ligand

F Zipp, R Martin, R Lichtenfels, W Roth, J Dichgans, PH Krammer, and M Weller
J Immunol 1997 159: 2108-2115. [Abstract] [PDF]  

Amplified follicular immune complex deposition in mice lacking the Fc receptor gamma-chain does not alter maturation of the B cell response

KA Vora, JV Ravetch, and T Manser
J Immunol 1997 159: 2116-2124. [Abstract] [PDF]  

A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma

HJ Ahn, S Maruo, M Tomura, J Mu, T Hamaoka, K Nakanishi, S Clark, M Kurimoto, H Okamura, and H Fujiwara
J Immunol 1997 159: 2125-2131. [Abstract] [PDF]  

CD4 T cell anergy in murine AIDS: costimulation via CD28 and the addition of IL-12 are not sufficient to rescue anergic CD4 T cells

C Andrews, SL Swain, and G Muralidhar
J Immunol 1997 159: 2132-2138. [Abstract] [PDF]  

The effect of the proteasome inhibitor lactacystin on the presentation of transporter associated with antigen processing (TAP)-dependent and TAP-independent peptide epitopes by class I molecules

A Bai and J Forman
J Immunol 1997 159: 2139-2146. [Abstract] [PDF]  

Non-MHC-linked Th2 cell development induced by soluble protein administration predicts susceptibility to Leishmania major infection

JC Guery, F Galbiati, S Smiroldo, and L Adorini
J Immunol 1997 159: 2147-2153. [Abstract] [PDF]  

CD94 ligation induces apoptosis in a subset of IL-2-stimulated NK cells

H Ida, MJ Robertson, S Voss, J Ritz, and P Anderson
J Immunol 1997 159: 2154-2160. [Abstract] [PDF]  

Interleukin-11 inhibits macrophage interleukin-12 production

SX Leng and JA Elias
J Immunol 1997 159: 2161-2168. [Abstract] [PDF]  

CD28-induced cytokine production and proliferation by thymocytes are differentially regulated by the p59fyn tyrosine kinase

CJ Ong, AS Lim, and HS Teh
J Immunol 1997 159: 2169-2176. [Abstract] [PDF]  

Impaired class II expression and antigen uptake in monocytic cells after HIV-1 infection

S Polyak, H Chen, D Hirsch, I George, R Hershberg, and K Sperber
J Immunol 1997 159: 2177-2188. [Abstract] [PDF]  

T cells bearing Vbeta8 are preferentially infected with exogenous mouse mammary tumor virus

N Upragarin, H Nishimura, W Wajjwalku, Y Ando, S Nagafuchi, T Watanabe, and Y Yoshikai
J Immunol 1997 159: 2189-2195. [Abstract] [PDF]  

Fas ligand expression is restricted to nonlymphoid thymic components in situ

LE French, A Wilson, M Hahne, I Viard, J Tschopp, and HR MacDonald
J Immunol 1997 159: 2196-2202. [Abstract] [PDF]  

Antibodies against sialophorin (CD43) enhance the capacity of dendritic cells to cluster and activate T lymphocytes

E Fanales-Belasio, G Zambruno, A Cavani, and G Girolomoni
J Immunol 1997 159: 2203-2211. [Abstract] [PDF]  

IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade

A Ogata, D Chauhan, G Teoh, SP Treon, M Urashima, RL Schlossman, and KC Anderson
J Immunol 1997 159: 2212-2221. [Abstract] [PDF]  

Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand- treated mice

B Pulendran, J Lingappa, MK Kennedy, J Smith, M Teepe, A Rudensky, CR Maliszewski, and E Maraskovsky
J Immunol 1997 159: 2222-2231. [Abstract] [PDF]  

Distinct mechanisms for the induction and maintenance of allograft tolerance with CTLA4-Fc treatment

HM Tran, PW Nickerson, AC Restifo, MA Ivis-Woodward, A Patel, RD Allen, TB Strom, and PJ O'Connell
J Immunol 1997 159: 2232-2239. [Abstract] [PDF]  

Cultured NK1.1+ CD4+ T cells produce large amounts of IL-4 and IFN- gamma upon activation by anti-CD3 or CD1

H Chen and WE Paul
J Immunol 1997 159: 2240-2249. [Abstract] [PDF]  

CD99 (MIC2) regulates the LFA-1/ICAM-1-mediated adhesion of lymphocytes, and its gene encodes both positive and negative regulators of cellular adhesion

JH Hahn, MK Kim, EY Choi, SH Kim, HW Sohn, DI Ham, DH Chung, TJ Kim, WJ Lee, CK Park, HJ Ree, and SH Park
J Immunol 1997 159: 2250-2258. [Abstract] [PDF]  

IL-7 activates alpha4beta1 integrin in murine thymocytes

H Kitazawa, K Muegge, R Badolato, JM Wang, WE Fogler, DK Ferris, CK Lee, S Candeias, MR Smith, JJ Oppenheim, and SK Durum
J Immunol 1997 159: 2259-2264. [Abstract] [PDF]  

The proliferative in vivo activities of lpr double-negative T cells and the primary role of p59fyn in their activation and expansion

D Balomenos, R Rumold, and AN Theofilopoulos
J Immunol 1997 159: 2265-2273. [Abstract] [PDF]  

Convergence of Schiff base costimulatory signaling and TCR signaling at the level of mitogen-activated protein kinase ERK2

H Chen, S Hall, B Heffernan, NT Thompson, MV Rogers, and J Rhodes
J Immunol 1997 159: 2274-2281. [Abstract] [PDF]  

CD40 ligand induction on T cell subsets by peptide-presenting B cells: implications for development of the primary T and B cell response

AI Jaiswal and M Croft
J Immunol 1997 159: 2282-2291. [Abstract] [PDF]  

The Lck SH2 phosphotyrosine binding site is critical for efficient TCR- induced processive tyrosine phosphorylation of the zeta-chain and IL-2 production

LA Lewis, CD Chung, J Chen, JR Parnes, M Moran, VP Patel, and MC Miceli
J Immunol 1997 159: 2292-2300. [Abstract] [PDF]  

Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo

LA O'Reilly, AW Harris, DM Tarlinton, LM Corcoran, and A Strasser
J Immunol 1997 159: 2301-2311. [Abstract] [PDF]  

Functional mapping of the orientation for TCR recognition of an H2-Kb- restricted ovalbumin peptide suggests that the beta-chain subunit can dominate the determination of peptide side chain specificity

SJ Turner, SC Jameson, and FR Carbone
J Immunol 1997 159: 2312-2317. [Abstract] [PDF]  

Analysis of polymorphism in porcine MHC class I genes: alterations in signals recognized by human cytotoxic lymphocytes

JA Sullivan, HF Oettinger, DH Sachs, and AS Edge
J Immunol 1997 159: 2318-2326. [Abstract] [PDF]  

The glycosylation of IgA produced by murine B cells is altered by Th2 cytokines

SR Chintalacharuvu and SN Emancipator
J Immunol 1997 159: 2327-2333. [Abstract] [PDF]  

T cell-independent response to Brucella-insulin identifies a preimmune repertoire for insulin

JW Thomas, PM Kralick, and UK Ewulonu
J Immunol 1997 159: 2334-2341. [Abstract] [PDF]  

Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor

JP Arm, C Nwankwo, and KF Austen
J Immunol 1997 159: 2342-2349. [Abstract] [PDF]  

Absence of functional relevance of human transporter associated with antigen processing polymorphism for peptide selection

S Daniel, S Caillat-Zucman, J Hammer, JF Bach, and PM van Endert
J Immunol 1997 159: 2350-2357. [Abstract] [PDF]  

Assembly and retention of CD1b heavy chains in the endoplasmic reticulum

M Sugita, SA Porcelli, and MB Brenner
J Immunol 1997 159: 2358-2365. [Abstract] [PDF]  

Cytolytic T lymphocyte recognition of the immunodominant HLA-A*0201- restricted Melan-A/MART-1 antigenic peptide in melanoma

P Romero, N Gervois, J Schneider, P Escobar, D Valmori, C Pannetier, A Steinle, T Wolfel, D Lienard, V Brichard, A van Pel, F Jotereau, and JC Cerottini
J Immunol 1997 159: 2366-2374. [Abstract] [PDF]  

Heat shock protein 65 induced by gammadelta T cells prevents apoptosis of macrophages and contributes to host defense in mice infected with Toxoplasma gondii

H Hisaeda, T Sakai, H Ishikawa, Y Maekawa, K Yasutomo, RA Good, and K Himeno
J Immunol 1997 159: 2375-2381. [Abstract] [PDF]  

Superantigen activation of immune cells evokes epithelial (T84) transport and barrier abnormalities via IFN-gamma and TNF alpha: inhibition of increased permeability, but not diminished secretory responses by TGF-beta2

DM McKay and PK Singh
J Immunol 1997 159: 2382-2390. [Abstract] [PDF]  

Chimeric peptides: a new approach to enhancing the immunogenicity of peptides with low MHC class I affinity: application in antiviral vaccination

S Tourdot, M Oukka, JC Manuguerra, V Magafa, I Vergnon, N Riche, M Bruley- Rosset, P Cordopatis, and K Kosmatopoulos
J Immunol 1997 159: 2391-2398. [Abstract] [PDF]  

Growth of P511 mastocytoma cells in BALB/c mouse brain elicits CTL response without tumor elimination: a new tumor model for regional central nervous system immunity

LB Gordon, SC Nolan, HF Cserr, PM Knopf, and CJ Harling-Berg
J Immunol 1997 159: 2399-2408. [Abstract] [PDF]  

Adsorption to aluminum hydroxide promotes the activity of IL-12 as an adjuvant for antibody as well as type 1 cytokine responses to HIV-1 gp120

D Jankovic, P Caspar, M Zweig, M Garcia-Moll, SD Showalter, FR Vogel, and A Sher
J Immunol 1997 159: 2409-2417. [Abstract] [PDF]  

Hydrogen peroxide-mediated transcriptional induction of macrophage colony-stimulating factor by TGF-beta1

YH Hong, HB Peng, V La Fata, and JK Liao
J Immunol 1997 159: 2418-2423. [Abstract] [PDF]  

Human monocyte binding to fibronectin enhances IFN-gamma-induced early signaling events

JB McCarthy, BV Vachhani, SM Wahl, DS Finbloom, and GM Feldman
J Immunol 1997 159: 2424-2430. [Abstract] [PDF]  

Regulation of tissue inhibitor of metalloproteinase-1 in fibroblasts and acute phase proteins in hepatocytes in vitro by mouse oncostatin M, cardiotrophin-1, and IL-6

CD Richards, C Kerr, M Tanaka, T Hara, A Miyajima, D Pennica, F Botelho, and CM Langdon
J Immunol 1997 159: 2431-2437. [Abstract] [PDF]  

Characterization of C3-binding proteins on mouse neutrophils and platelets

RJ Quigg, JJ Alexander, CF Lo, A Lim, C He, and VM Holers
J Immunol 1997 159: 2438-2444. [Abstract] [PDF]  

Enhanced expression of inducible cyclooxygenase with age in murine macrophages

MG Hayek, C Mura, D Wu, AA Beharka, SN Han, KE Paulson, D Hwang, and SN Meydani
J Immunol 1997 159: 2445-2451. [Abstract] [PDF]  

Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice

M Labow, D Shuster, M Zetterstrom, P Nunes, R Terry, EB Cullinan, T Bartfai, C Solorzano, LL Moldawer, R Chizzonite, and KW McIntyre
J Immunol 1997 159: 2452-2461. [Abstract] [PDF]  

Chitin particle-induced cell-mediated immunity is inhibited by soluble mannan: mannose receptor-mediated phagocytosis initiates IL-12 production

Y Shibata, WJ Metzger, and QN Myrvik
J Immunol 1997 159: 2462-2467. [Abstract] [PDF]  

Bridging of neutrophils to target cells by opsonized zymosan enhances the cytotoxicity of neutrophil-produced H2O2

X Jiang, TH Wu, and RL Rubin
J Immunol 1997 159: 2468-2475. [Abstract] [PDF]  

In vivo transfer of engineered macrophages into the glomerulus: endogenous TGF-beta-mediated defense against macrophage-induced glomerular cell activation

TS Suto, LG Fine, F Shimizu, and M Kitamura
J Immunol 1997 159: 2476-2483. [Abstract] [PDF]  

Repeated elicitation of contact hypersensitivity induces a shift in cutaneous cytokine milieu from a T helper cell type 1 to a T helper cell type 2 profile

H Kitagaki, N Ono, K Hayakawa, T Kitazawa, K Watanabe, and T Shiohara
J Immunol 1997 159: 2484-2491. [Abstract] [PDF]  

Induction of IL-12 and chemokines by hyaluronan requires adhesion- dependent priming of resident but not elicited macrophages

J Hodge-Dufour, PW Noble, MR Horton, C Bao, M Wysoka, MD Burdick, RM Strieter, G Trinchieri, and E Pure
J Immunol 1997 159: 2492-2500. [Abstract] [PDF]  

Changes in cytokine secretion induced by altered peptide ligands of myelin basic protein peptide 85-99

LJ Ausubel, JI Krieger, and DA Hafler
J Immunol 1997 159: 2502-2512. [Abstract] [PDF]  

Functional heterogeneity of HLA-A*02 subtypes revealed by presentation of a MAGE-3-encoded peptide to cytotoxic T cell clones

K Fleischhauer, S Tanzarella, V Russo, ML Sensi, P van der Bruggen, C Bordignon, and C Traversari
J Immunol 1997 159: 2513-2521. [Abstract] [PDF]  

Prevention by anti-LFA-1 of acute myoblast death following transplantation

B Guerette, D Skuk, F Celestin, C Huard, F Tardif, I Asselin, B Roy, M Goulet, R Roy, M Entman, and JP Tremblay
J Immunol 1997 159: 2522-2531. [Abstract] [PDF]  

Suppression of autoimmune disease and of massive lymphadenopathy in MRL/Mp-lpr/lpr mice lacking tyrosine kinase Fyn (p59fyn)

T Takahashi, T Yagi, S Kakinuma, A Kurokawa, T Okada, K Takatsu, S Aizawa, and T Katagiri
J Immunol 1997 159: 2532-2541. [Abstract] [PDF]  

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